Afshin Samali (A Samali)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 29

Top Venues

Cell death & disease

Cells

Journal of cellular and molecular medicine

Cancers

National University of Ireland - Galway

University College Cork National University of Ireland (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National University of Ireland - Galway Jan 01 2000

Ireland

Prof of Biochemistry :: Biochemistry

Karolinska Institutet Apr 01 1997 - Dec 31 1999

Sweden

Postdoctoral Researcher :: Institute for Environmental Medicine

Education History

University College Cork National University of Ireland Oct 01 1993 - Mar 10 1997

Ireland

PHD :: Biochemistry

National University of Ireland Maynooth Sep 01 1989 - Jun 10 1993

Ireland

BSC :: Biology

Publications

Sanaz Dastghaib, Shahla Shojaei, Zohreh Mostafavi-Pour, Pawan Sharma, John B Patterson, Afshin Samali, Pooneh Mokarram, Saeid Ghavmi
Correction: Dastghaib et al. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells 2020, 9 , 2339. Cells 13 (8) (2024)
Sanaz Dastghaib, Shahla Shojaei, Zohreh Mostafavi-Pour, Pawan Sharma, John B Patterson, Afshin Samali, Pooneh Mokarram, Saeid Ghavmi
Correction: Dastghaib et al. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells 2020, 9 , 2339. Cells 13 (8) (2024)
Matthieu Moncan, Hassan Rakhsh-Khorshid, Leif A Eriksson, Afshin Samali, Adrienne M Gorman
Insights into the structure and function of the RNA ligase RtcB. Cellular and molecular life sciences : CMLS 80 (12) (2023)
Susan E Logue, Adrienne M Gorman, Afshin Samali
New insights into IRE1α activation and function in anti-tumor immunity. The Journal of cell biology 221 (6) (2022)
Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M Robinson, Giovanny Rodriguez Blanco, Sylwia Kierszniowska, Eoghan P McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V Swinnen, Aristotelis Chatziioannou, Éric Chevet, Adrienne M Gorman, Afshin Samali
Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer. Nature communications 13 (1) (2022)
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares-Lupon, Kathleen Schmit, Pierre-Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Éric Chevet
Dual IRE1 RNase functions dictate glioblastoma development. EMBO molecular medicine 14 (2) (2022)
Stuart Creedican, Claire M Robinson, Katarzyna Mnich, Md Nahidul Islam, Eva Szegezdi, Ruth Clifford, Janusz Krawczyk, John B Patterson, Stephen P FitzGerald, Mark Summers, Ciaran Richardson, Kenneth Martin, Adrienne M Gorman, Afshin Samali
Inhibition of IRE1α RNase activity sensitizes patient-derived acute myeloid leukaemia cells to proteasome inhibitors. Journal of cellular and molecular medicine 26 (16) (2022)
Matthieu Moncan, Katarzyna Mnich, Arnaud Blomme, Aitor Almanza, Afshin Samali, Adrienne M Gorman
Regulation of lipid metabolism by the unfolded protein response. Journal of cellular and molecular medicine 25 (3) (2021)
Pawan Sharma, Javad Alizadeh, Maya Juarez, Afshin Samali, Andrew J Halayko, Nicholas J Kenyon, Saeid Ghavmi, Amir A Zeki
Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis. Cells 10 (7) (2021)
Danielle E Read, Ananya Gupta, Karen Cawley, Laura Fontana, Patrizia Agostinis, Afshin Samali, Sanjeev Gupta
Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis. Life (Basel, Switzerland) 11 (1) (2021)
Katarzyna Mnich, Izabela Koryga, Karolina Pakos-Zebrucka, Melissa Thomas, Susan E Logue, Leif A Eriksson, Adrienne M Gorman, Afshin Samali
The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner. Journal of cellular and molecular medicine 25 (18) (2021)
Claire M Robinson, Aaron Talty, Susan E Logue, Katarzyna Mnich, Adrienne M Gorman, Afshin Samali
An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer. Cancers 13 (2) (2021)
Mahmoud Aghaei, Ahmad Nasimian, Marveh Rahmati, Philip Kawalec, Filip Machaj, Jakub Rosik, Bhavya Bhushan, S Zahra Bathaie, Negar Azarpira, Marek Jan Łos, Afshin Samali, David Perrin, Joseph W Gordon, Saeid Ghavmi
The Role of BiP and the IRE1α-XBP1 Axis in Rhabdomyosarcoma Pathology. Cancers 13 (19) (2021)
Chetan Chintha, Antonio Carlesso, Adrienne M Gorman, Afshin Samali, Leif A Eriksson
Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1. RSC advances 10 (1) (2020)
Sanaz Dastghaib, Shahla Shojaei, Zohreh Mostafavi-Pour, Pawan Sharma, John B Patterson, Afshin Samali, Pooneh Mokarram, Saeid Ghavmi
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells 9 (11) (2020)
Dimitrios Doultsinos, Antonio Carlesso, Chetan Chintha, James C Paton, Adrienne W Paton, Afshin Samali, Éric Chevet, Leif A Eriksson
Peptidomimetic-based identification of FDA-approved compounds inhibiting IRE1 activity. The FEBS journal 288 (3) (2020)
Aaron Talty, Shane Deegan, Mila Ljujic, Katarzyna Mnich, Serika D Naicker, Dagmar Quandt, Qingping Zeng, John B Patterson, Adrienne M Gorman, Matthew D Griffin, Afshin Samali, Susan E Logue
Correction: Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β. Cell death & disease 11 (1) (2020)
Leila Tabrizi, Kerry Thompson, Katarzyna Mnich, Chetan Chintha, Adrienne M Gorman, Liam Morrison, Janna Luessing, Noel F Lowndes, Peter Dockery, Afshin Samali, Andrea Erxleben
Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects. Molecular pharmaceutics 17 (8) (2020)
Marion Maurel, Joanna Obacz, Tony Avril, Yong-Ping Ding, Olga Papadodima, Xavier Treton, Fanny Daniel, Eleftherios Pilalis, Johanna Hörberg, Wenyang Hou, Marie-Claude Beauchamp, Julien Tourneur-Marsille, Dominique Cazals-Hatem, Lucia Sommerova, Afshin Samali, Jan Tavernier, Roman Hrstka, Aurélien Dupont, Delphine Fessart, Frédéric Delom, Martin E Fernandez-Zapico, Gregor Jansen, Leif A Eriksson, David Y Thomas, Loydie Jerome-Majewska, Ted Hupp, Aristotelis Chatziioannou, Éric Chevet, Eric Ogier-Denis
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation. EMBO molecular medicine 11 (6) (2020)
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares-Lupon, Kathleen Schmit, Pierre-Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Éric Chevet
Dual IRE1 RNase functions dictate glioblastoma development. EMBO molecular medicine 10 (3) (2019)
Antonio Carlesso, Chetan Chintha, Adrienne M Gorman, Afshin Samali, Leif A Eriksson
Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors. Scientific reports 9 (1) (2019)
Aaron Talty, Shane Deegan, Mila Ljujic, Katarzyna Mnich, Serika D Naicker, Dagmar Quandt, Qingping Zeng, John B Patterson, Adrienne M Gorman, Matthew D Griffin, Afshin Samali, Susan E Logue
Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β. Cell death & disease 10 (9) (2019)
Mohamed Mahameed, Thomas Wilhelm, Odai Darawshi, Akram Obiedat, Weiss-Sadan Tommy, Chetan Chintha, Thomas Schubert, Afshin Samali, Eric Chevet, Leif A Eriksson, Michael Huber, Boaz Tirosh
The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. Cell death & disease 10 (4) (2019)
Eoghan P McGrath, Susan E Logue, Katarzyna Mnich, Shane Deegan, Richard Jäger, Adrienne M Gorman, Afshin Samali
The Unfolded Protein Response in Breast Cancer. Cancers 10 (10) (2018)
Susan E Logue, Eoghan P McGrath, Patricia Cleary, Stephanie Greene, Katarzyna Mnich, Aitor Almanza, Eric Chevet, Róisín M Dwyer, Anup M Oommen, Patrick Legembre, Florence Godey, Emma C Madden, Brian Leuzzi, Joanna Obacz, Qingping Zeng, John B Patterson, Richard Jäger, Adrienne M Gorman, Afshin Samali
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. Nature communications 9 (1) (2018)
Eimear O' Reilly, Sukhraj Pal S Dhami, Denis V Baev, Csaba Ortutay, Anna Halpin-McCormick, Ruth Morrell, Corrado Santocanale, Afshin Samali, John Quinn, Michael E O'Dwyer, Eva Szegezdi
Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML. Scientific reports 8 (1) (2018)
Emma Madden, Susan E Logue, Sandra J Healy, Serge Manie, Afshin Samali
The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistance. Biology of the cell 111 (1) (2018)
Donna Kennedy, Katarzyna Mnich, Deepu Oommen, Reka Chakravarthy, Leonardo Almeida-Souza, Michiel Krols, Svetlana Saveljeva, Karen Doyle, Sanjeev Gupta, Vincent Timmerman, Sophie Janssens, Adrienne M Gorman, Afshin Samali
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis. Cell death & disease 8 (8) (2017)
Karolina Pakos-Zebrucka, Izabela Koryga, Katarzyna Mnich, Mila Ljujic, Afshin Samali, Adrienne M Gorman
The integrated stress response. EMBO reports 17 (10) (2016)
L O'Leary, A M van der Sloot, C R Reis, S Deegan, A E Ryan, S P S Dhami, L S Murillo, R H Cool, P Correa de Sampaio, K Thompson, G Murphy, W J Quax, L Serrano, Afshin Samali, E Szegezdi
Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity. Oncogene 35 (10) (2015)
Svetlana Saveljeva, S L Mc Laughlin, P Vandenabeele, Afshin Samali, M J M Bertrand
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells. Cell death & disease 6 (2015)
K Mnich, L A Carleton, E T Kavanagh, K M Doyle, Afshin Samali, A M Gorman
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner. Cell death & disease 5 (2014)

Afshin Samali.css-eqlu8i{font-size:small;padding-left:4px;} (A Samali)

Publication Activity (10 Years)

Top Topics

Top Venues

Afshin Samali (A Samali)