Alfred L Goldberg (Alfred Goldberg)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2022
Publications (10 Years): 9

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

The Journal of cell biology

Nature medicine

Nature communications

Harvard Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School

United States

Prof. :: Cell Biology

Publications

Donghoon Lee, Alfred L Goldberg
26S proteasomes become stably activated upon heat shock when ubiquitination and protein degradation increase. Proceedings of the National Academy of Sciences of the United States of America 119 (25) (2022)
Alfred L Goldberg, Hyoung Tae Kim, Donghoon Lee, Galen Andrew Collins
Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation. Biomolecules 11 (6) (2021)
Galen A Collins, Alfred L Goldberg
Proteins containing ubiquitin-like (Ubl) domains not only bind to 26S proteasomes but also induce their activation. Proceedings of the National Academy of Sciences of the United States of America 117 (9) (2020)
Zhe Sha, Alfred L Goldberg
Multiple myeloma cells are exceptionally sensitive to heat shock, which overwhelms their proteostasis network and induces apoptosis. Proceedings of the National Academy of Sciences of the United States of America 117 (35) (2020)
Jordan J S VerPlank, Sylwia D Tyrkalska, Angeleen Fleming, David C Rubinsztein, Alfred L Goldberg
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America 117 (25) (2020)
Siavash Vahidi, Zev A Ripstein, Jordan B Juravsky, Enrico Rennella, Alfred L Goldberg, Anthony K Mittermaier, John L Rubinstein, Lewis E Kay
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Zhe Sha, Helena Maria Schnell, Kerstin Ruoff, Alfred L Goldberg
Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation. The Journal of cell biology 217 (5) (2018)
Giulia Milan, Vanina Romanello, Francesca Pescatore, Andrea Armani, Ji-Hye Paik, Laura Frasson, Anke Seydel, Jinghui Zhao, Reimar Abraham, Alfred L Goldberg, Bert Blaauw, Ronald A DePinho, Marco Sandri
Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nature communications 6 (2015)
Natura Myeku, Catherine L Clelland, Sheina Emrani, Nikolay V Kukushkin, Wai Haung Yu, Alfred L Goldberg, Karen E Duff
Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling. Nature medicine 22 (1) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alfred L Goldberg (Alfred Goldberg)