Charles E McKenna

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 27

Top Topics

Single Molecule

Structural Basis

Multiple Myeloma

Top Venues

Journal of the American Chemical Society

Bioconjugate chemistry

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry (2024)
Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry 63 (11) (2024)
Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry 63 (11) (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society 146 (5) (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society 146 (5) (2024)
Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry 63 (11) (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society 146 (5) (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. Journal of the American Chemical Society 146 (5) (2024)
Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry 63 (11) (2024)
Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz, Cristian Chavira, Amirsoheil Negahbani, Maryam Nakhjiri, Corinne Minard, Beatriz Garcia-Barboza, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Joann B Sweasy
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β. Biochemistry (2024)
Leah M Seebald, Pouya Haratipour, Michaela R Jacobs, Hannah M Bernstein, Boris A Kashemirov, Charles E McKenna, Barbara Imperiali
Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies. bioRxiv : the preprint server for biology (2023)
Hiroko Okawa, Takeru Kondo, Akishige Hokugo, Philip Cherian, Oskar Sundberg, Jesus J Campagna, Boris A Kashemirov, Varghese John, Shuting Sun, Frank H Ebetino, Charles E McKenna, Ichiro Nishimura
Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice. Communications medicine 2 (2022)
Hiroko Okawa, Takeru Kondo, Akishige Hokugo, Philip Cherian, Jesus J Campagna, Nicholas A Lentini, Eric C Sung, Samantha Chiang, Yi-Ling Lin, Frank H Ebetino, Varghese John, Shuting Sun, Charles E McKenna, Ichiro Nishimura
Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate. eLife 11 (2022)
Takeru Kondo, Hiroko Okawa, Akishige Hokugo, Bhumika Shokeen, Oskar Sundberg, Yiying Zheng, Charles E McKenna, Renate Lux, Ichiro Nishimura
Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice. Communications biology 5 (1) (2022)
Yingsheng Zhou, Justin M Overhulse, Nathan J Dupper, Yanchun Guo, Boris A Kashemirov, Kaiyao Wei, Jérôme Govin, Carlo Petosa, Charles E McKenna
Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding. Journal of computational chemistry 43 (32) (2022)
Eric T Richard, Kenzo Morinaga, Yiying Zheng, Oskar Sundberg, Akishige Hokugo, Kimberly Hui, Yipin Zhou, Hodaka Sasaki, Boris A Kashemirov, Ichiro Nishimura, Charles E McKenna
Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model. Bioconjugate chemistry 32 (5) (2021)
Katherin Patsch, Chao Liu, Grzegorz Zapotoczny, Yuanye Sun, Harish Sura, Nolan Ung, Ren X Sun, Bethany Haliday, Chen Yu, Mayada Aljehani, Jerry S H Lee, Boris A Kashemirov, David B Agus, Charles E McKenna, Daniel Ruderman
Paradoxical androgen receptor regulation by small molecule enantiomers. Proceedings of the National Academy of Sciences of the United States of America 118 (12) (2021)
Nichole J Pedowitz, Emma G Jackson, Justin M Overhulse, Charles E McKenna, Jennifer J Kohler, Matthew R Pratt
Anomeric Fatty Acid Functionalization Prevents Nonenzymatic S-Glycosylation by Monosaccharide Metabolic Chemical Reporters. ACS chemical biology 16 (10) (2021)
Pouya Haratipour, Corinne Minard, Maryam Nakhjiri, Amirsoheil Negahbani, Brian T Chamberlain, Jorge Osuna, Thomas G Upton, Michelle Zhao, Boris A Kashemirov, Charles E McKenna
Completing the β,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and 31P and 19F NMR Correlations with Absolute Configurations. The Journal of organic chemistry 85 (22) (2020)
Vinod K Batra, Khadijeh S Alnajjar, Joann B Sweasy, Charles E McKenna, Myron F Goodman, Samuel H Wilson
Revealing an Internal Stabilization Deficiency in the DNA Polymerase β K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry 59 (8) (2020)
Noah A Setterholm, Pouya Haratipour, Boris A Kashemirov, Charles E McKenna, Gerald F Joyce
Kinetic Effects of β,γ-Modified Deoxynucleoside 5'-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA. Biochemistry 60 (1) (2020)
Keriann Oertell, Jan Florián, Pouya Haratipour, Takamitsu A Kato, Boris A Kashemirov, Samuel H Wilson, Charles E McKenna, Myron F Goodman
A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β. Biochemistry 58 (13) (2019)
Judith S Kempfle, Kim Nguyen, Christine Hamadani, Nicholas Koen, Albert S Edge, Boris A Kashemirov, David H Jung, Charles E McKenna
Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss. Bioconjugate chemistry 29 (4) (2018)
Vinod K Batra, Keriann Oertell, William A Beard, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, Samuel H Wilson
Mapping Functional Substrate-Enzyme Interactions in the pol β Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry 57 (26) (2018)
Keriann Oertell, Boris A Kashemirov, Amirsoheil Negahbani, Corinne Minard, Pouya Haratipour, Khadijeh S Alnajjar, Joann B Sweasy, Vinod K Batra, William A Beard, Samuel H Wilson, Charles E McKenna, Myron F Goodman
Probing DNA Base-Dependent Leaving Group Kinetic Effects on the DNA Polymerase Transition State. Biochemistry 57 (26) (2018)