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Cleydson Breno Rodrigues Dos Santos (Cleydson B R Dos Santos, C B R Santos, Cleydson B R Santos, Cleydson B R Santos)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 45

Top Venues

Molecules (Basel, Switzerland)

Pharmaceuticals (Basel, Switzerland)

Journal of biomolecular structure & dynamics

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Ruan S Bastos, Lúcio R de Lima, Moysés F A Neto, null Maryam, Numan Yousaf, Jorddy Nevez Cruz, Joaquín Maria Campos Rosa, Njogu M Kimani, Ryan da Silva Ramos, Cleydson Breno Rodrigues Dos Santos
Design and Identification of Inhibitors for the Spike-ACE2 Target of SARS-CoV-2. International journal of molecular sciences 24 (10) (2023)
Lana P S Oliveira, Lúcio R Lima, Luciane B Silva, Jorddy Nevez Cruz, Ryan da Silva Ramos, Luciana S Lima, Francy M N Cardoso, Aderaldo V Silva, Dália P Rodrigues, Gabriela S Rodrigues, Aldo Aparecido Proietti-Junior, Gabriela B Dos Santos, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Hierarchical Virtual Screening of Potential New Antibiotics from Polyoxygenated Dibenzofurans against Staphylococcus aureus Strains. Pharmaceuticals (Basel, Switzerland) 16 (10) (2023)
Cleydson Breno Rodrigues Dos Santos, Cleison C Lobato, Sirlene S B Ota, Raí C Silva, Renata C V S Bittencourt, Jofre Jacob da Silva Freitas, Elenilze F B Ferreira, Marília B Ferreira, Renata Cunha Silva, Anderson B De Lima, Joaquín Maria Campos Rosa, Rosivaldo S Borges, José A H M Bittencourt
Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions. Pharmaceuticals (Basel, Switzerland) 16 (11) (2023)
Luciane B Silva, Elenilze F B Ferreira, Maryam, Jose Manuel Espejo-Roman, Glauber V Costa, Josiane V Cruz, Njogu M Kimani, Josivan da Silva Costa, José A H M Bittencourt, Jorddy Nevez Cruz, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach. Molecules (Basel, Switzerland) 28 (3) (2023)
Emanuelle T Rodrigues, Paulo Peretti, Roberto M Bezerra, Manoel F Biancardi, Francisco Fábio Oliveira de Sousa, Elizabeth P Mendes, João B R Dutra, Carla C R Silveira, Carlos H Castro, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Fernanda Cristina Alcantara Dos Santos, Mayara T Pinheiro
Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation. Evidence-based complementary and alternative medicine : eCAM 2023 (2023)
Emanuelle T Rodrigues, Paulo Peretti, Roberto M Bezerra, Manoel F Biancardi, Francisco Fábio Oliveira de Sousa, Elizabeth P Mendes, João B R Dutra, Carla C R Silveira, Carlos H Castro, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Fernanda Cristina Alcantara Dos Santos, Mayara T Pinheiro
Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation. Evidence-based complementary and alternative medicine : eCAM 2023 (2023)
Danielle Figuerêdo da Silva, Jéssica Lima de Souza, Diego Mota da Costa, David Bacelar Costa, Paulo Otávio Lourenço Moreira, Amanda Luisa da Fonseca, Fernando de Pilla Varotti, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Clayton Queiroz Alves, Franco Henrique Andrade Leite, Hugo Neves Brandão
Antiplasmodial activity of coumarins isolated from Polygala boliviensis : in vitro and in silico studies. Journal of biomolecular structure & dynamics (2023)
Raquel B M de Almeida, Deyse B Barbosa, Mayra R do Bomfim, Jéssika A O Amparo, Bruno Silva Andrade, Silvia Lima Costa, Joaquín Maria Campos Rosa, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Franco Henrique Andrade Leite, Mariana Borges Botura
Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Jorddy Nevez Cruz, Mozaniel Santana de Oliveira, Marcia Moraes Cascaes, Suraj N Mali, Srushti M Tambe, Cleydson Breno Rodrigues Dos Santos, Maria das Graças Bichara Zoghbi, Eloísa Helena de Aguiar Andrade
Variation in the Chemical Composition of Endemic Specimens of Hedychium coronarium J. Koenig from the Amazon and In Silico Investigation of the ADME/Tox Properties of the Major Compounds. Plants (Basel, Switzerland) 12 (14) (2023)
Raquel B M de Almeida, Deyse B Barbosa, Mayra R do Bomfim, Jéssika A O Amparo, Bruno Silva Andrade, Silvia Lima Costa, Joaquín Maria Campos Rosa, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Franco Henrique Andrade Leite, Mariana Borges Botura
Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Raquel B M de Almeida, Deyse B Barbosa, Mayra R do Bomfim, Jéssika A O Amparo, Bruno Silva Andrade, Silvia Lima Costa, Joaquín Maria Campos Rosa, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Franco Henrique Andrade Leite, Mariana Borges Botura
Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Luciane B Silva, Elenilze F B Ferreira, Maryam, Jose Manuel Espejo-Roman, Glauber V Costa, Josiane V Cruz, Njogu M Kimani, Josivan da Silva Costa, José A H M Bittencourt, Jorddy Nevez Cruz, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach. Molecules (Basel, Switzerland) 28 (3) (2023)
Njogu M Kimani, Charles O Ochieng, Mike Don Ogutu, Kevin Otieno Yamo, Joab Otieno Onyango, Cleydson Breno Rodrigues Dos Santos
Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase. Journal of xenobiotics 13 (1) (2023)
Njogu M Kimani, Charles O Ochieng, Mike Don Ogutu, Kevin Otieno Yamo, Joab Otieno Onyango, Cleydson Breno Rodrigues Dos Santos
Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase. Journal of xenobiotics 13 (1) (2023)
Raquel B M de Almeida, Deyse B Barbosa, Mayra R do Bomfim, Jéssika A O Amparo, Bruno Silva Andrade, Silvia Lima Costa, Joaquín Maria Campos Rosa, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Franco Henrique Andrade Leite, Mariana Borges Botura
Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Njogu M Kimani, Charles O Ochieng, Mike Don Ogutu, Kevin Otieno Yamo, Joab Otieno Onyango, Cleydson Breno Rodrigues Dos Santos
Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase. Journal of xenobiotics 13 (1) (2023)
Njogu M Kimani, Charles O Ochieng, Mike Don Ogutu, Kevin Otieno Yamo, Joab Otieno Onyango, Cleydson Breno Rodrigues Dos Santos
Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase. Journal of xenobiotics 13 (1) (2023)
Luciane B Silva, Elenilze F B Ferreira, Maryam, Jose Manuel Espejo-Roman, Glauber V Costa, Josiane V Cruz, Njogu M Kimani, Josivan da Silva Costa, José A H M Bittencourt, Jorddy Nevez Cruz, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach. Molecules (Basel, Switzerland) 28 (3) (2023)
Ryan S Ramos, Rosivaldo S Borges, João S N de Souza, Inana F Araujo, Mariana H Chaves, Cleydson Breno Rodrigues Dos Santos
Identification of Potential Antiviral Inhibitors from Hydroxychloroquine and 1,2,4,5-Tetraoxanes Analogues and Investigation of the Mechanism of Action in SARS-CoV-2. International journal of molecular sciences 23 (3) (2022)
Moysés F A Neto, Joaquín Maria Campos Rosa, Amanda P M Cerqueira, Lucio R de Lima, Glauber V Da Costa, Ryan da Silva Ramos, Jairo T Magalhães Junior, Cleydson Breno Rodrigues Dos Santos, Franco Henrique Andrade Leite
Hierarchical Virtual Screening and Binding Free Energy Prediction of Potential Modulators of Aedes Aegypti Odorant-Binding Protein 1. Molecules (Basel, Switzerland) 27 (20) (2022)
Roberval Nascimento Moraes-Neto, Gabrielle Guedes Coutinho, Ana Caroline Santos Ataíde, Aline de Oliveira Rezende, Camila Evangelista Carnib Nascimento, Rafaela Pontes de Albuquerque, Cláudia Quintino da Rocha, Adriana Sousa Rêgo, Maria do Socorro de Sousa Cartágenes, Ana Lúcia Abreu-Silva, Igor Victor Ferreira Dos Santos, Cleydson Breno Rodrigues Dos Santos, Rosane Nassar Meireles Guerra, Rachel Melo Ribeiro, Valério Monteiro-Neto, Eduardo Martins de Sousa, Rafael Cardoso Carvalho
Ethyl Acetate Fraction of Bixa orellana and Its Component Ellagic Acid Exert Antibacterial and Anti-Inflammatory Properties against Mycobacterium abscessus subsp. massiliense . Antibiotics (Basel, Switzerland) 11 (6) (2022)
Lúcio R Lima, Ruan S Bastos, Elenilze F B Ferreira, Rozires P Leão, Pedro H F Araújo, Samuel Silva da Rocha Pita, Humberto Fonseca de Freitas, Jose Manuel Espejo-Roman, Edla L V S Dos Santos, Ryan da Silva Ramos, Williams J C Macêdo, Cleydson Breno Rodrigues Dos Santos
Identification of Potential New Aedes aegypti Juvenile Hormone Inhibitors from N-Acyl Piperidine Derivatives: A Bioinformatics Approach. International journal of molecular sciences 23 (17) (2022)
Glauber V Da Costa, Moysés F A Neto, Alicia K P Da Silva, Ester M F De Sá, Luanne C F Cancela, Jeanina S Vega, Cássio M Lobato, Juliana Pavan Zuliani, Jose Manuel Espejo-Roman, Joaquín Maria Campos Rosa, Franco H A Leite, Cleydson Breno Rodrigues Dos Santos
Identification of Potential Insect Growth Inhibitor against Aedes aegypti : A Bioinformatics Approach. International journal of molecular sciences 23 (15) (2022)
Renato A da Costa, João A P da Rocha, Alan S Pinheiro, Andréia do S S da Costa, Elaine C M da Rocha, Raí C Silva, Arlan da S Gonçalves, Cleydson Breno Rodrigues Dos Santos, Davi do S B Brasil
A Computational Approach Applied to the Study of Potential Allosteric Inhibitors Protease NS2B/NS3 from Dengue Virus. Molecules (Basel, Switzerland) 27 (13) (2022)
Guilherme Martins Silva, Rosivaldo S Borges, Kelton L B Dos Santos, Leonardo Bruno Federico, Isaque Antônio Galindo Francischini, Suzane Q Gomes, Mariana P Barcelos, Rai C Silva, Cleydson Breno Rodrigues Dos Santos, Carlos H T P Silva
Revisiting the Proposition of Binding Pockets and Bioactive Poses for GSK-3β Allosteric Modulators Addressed to Neurodegenerative Diseases. International journal of molecular sciences 22 (15) (2021)
Josiane V Cruz, Silvana Giuliatti, Levy Bueno Alves, Raí C Silva, Elenilze F B Ferreira, Njogu M Kimani, Carlos Henrique Tomich de Paula da Silva, João S N de Souza, Jose Manuel Espejo-Roman, Cleydson Breno Rodrigues Dos Santos
Identification of novel potential cyclooxygenase-2 inhibitors using ligand- and structure-based virtual screening approaches. Journal of biomolecular structure & dynamics (2021)
Raí C Silva, Humberto Fonseca de Freitas, Joaquín Maria Campos Rosa, Njogu M Kimani, Carlos H T P Silva, Rosivaldo S Borges, Samuel S R Pita, Cleydson Breno Rodrigues Dos Santos
Natural Products-Based Drug Design against SARS-CoV-2 Mpro 3CLpro. International journal of molecular sciences 22 (21) (2021)
Raimundo de A M Neto, Cleydson Breno Rodrigues Dos Santos, Shayanne V C Henriques, Letícia de O Machado, Jorddy Nevez Cruz, Carlos H T de P da Silva, Leonardo B Federico, Edivaldo H C de Oliveira, Michel P C de Souza, Patrícia N B da Silva, Carlton A Taft, Irlon Maciel Ferreira, Madson R F Gomes
Novel chalcones derivatives with potential antineoplastic activity investigated by docking and molecular dynamics simulations. Journal of biomolecular structure & dynamics (2020)
Ivanete C Palheta, Lanalice R Ferreira, Joyce Karen Lima Vale, Osmarina P P Silva, Anderson M Herculano, Karen R H M Oliveira, Antonio M J Chaves Neto, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos, Rosivaldo S Borges
Alkylated Sesamol Derivatives as Potent Antioxidants. Molecules (Basel, Switzerland) 25 (14) (2020)
Ana Mércia Silva Mascarenhas, Raquel Bianca Marchesine de Almeida, Moysés Fagundes de Araujo Neto, Géssica Oliveira Mendes, Jorddy Nevez Cruz, Cleydson Breno Rodrigues Dos Santos, Mariana Borges Botura, Franco Henrique Andrade Leite
Pharmacophore-based virtual screening and molecular docking to identify promising dual inhibitors of human acetylcholinesterase and butyrylcholinesterase. Journal of biomolecular structure & dynamics 39 (16) (2020)
Rozires P Leão, Josiane V Cruz, Glauber V da Costa, Jorddy Nevez Cruz, Elenilze F B Ferreira, Raí C Silva, Lúcio R de Lima, Rosivaldo S Borges, Gabriela B Dos Santos, Cleydson Breno Rodrigues Dos Santos
Identification of New Rofecoxib-Based Cyclooxygenase-2 Inhibitors: A Bioinformatics Approach. Pharmaceuticals (Basel, Switzerland) 13 (9) (2020)
Cleydson Breno Rodrigues Dos Santos, Kelton L B Dos Santos, Jorddy Nevez Cruz, Franco Henrique Andrade Leite, Rosivaldo S Borges, Carlton A Taft, Joaquín Maria Campos Rosa, Carlos Henrique Tomich de Paula da Silva
Molecular modeling approaches of selective adenosine receptor type 2A agonists as potential anti-inflammatory drugs. Journal of biomolecular structure & dynamics 39 (9) (2020)
E B Costa, Raí C Silva, Jose Manuel Espejo-Roman, M F de A Neto, Jorddy Nevez Cruz, Franco Henrique Andrade Leite, Carlos Henrique Tomich de Paula da Silva, J C Pinheiro, W J C Macêdo, Cleydson Breno Rodrigues Dos Santos
Chemometric methods in antimalarial drug design from 1,2,4,5-tetraoxanes analogues. SAR and QSAR in environmental research 31 (9) (2020)
Pedro H F Araújo, Ryan da Silva Ramos, Jorddy Nevez Cruz, Sebastião G Silva, Elenilze F B Ferreira, Lúcio R de Lima, Williams J C Macêdo, Jose Manuel Espejo-Roman, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches. Molecules (Basel, Switzerland) 25 (18) (2020)
Kelton L B Dos Santos, Jorddy Nevez Cruz, Luciane B Silva, Ryan da Silva Ramos, Moysés F A Neto, Cleison C Lobato, Sirlene S B Ota, Franco Henrique Andrade Leite, Rosivaldo S Borges, Carlos H T P da Silva, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches. Molecules (Basel, Switzerland) 25 (5) (2020)
Hady Keita, Cleydson Breno Rodrigues Dos Santos, Matheus Mercês Ramos, Elias Carvalho Padilha, Rodolfo Bortolozo Serafim, Andrés Navarrete Castro, Jesus Rafael Rodriguez Amado, Gabriel Monteiro da Silva, Irlon Maciel Ferreira, Silvana Giuliatti, José Carlos Tavares Carvalho
Assessment of the hypoglycemic effect of Bixin in alloxan-induced diabetic rats: in vivo and in silico studies. Journal of biomolecular structure & dynamics 39 (3) (2020)
Glauber V da Costa, Elenilze F B Ferreira, Ryan da Silva Ramos, Luciane B da Silva, Ester M F de Sá, Alicia K P da Silva, Cássio M Lobato, Raimundo N P Souto, Carlos Henrique T de P da Silva, Leonardo Bruno Federico, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos. Pharmaceuticals (Basel, Switzerland) 12 (2) (2019)
Elenilze F B Ferreira, Luciane B Silva, Glauber V Costa, Josivan da Silva Costa, Mayara A T Fujishima, Rozires P Leão, André L S Ferreira, Leonardo Bruno Federico, Carlos H T P Silva, Joaquín Maria Campos Rosa, Williams J C Macêdo, Cleydson Breno Rodrigues Dos Santos
Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening. Molecules (Basel, Switzerland) 24 (16) (2019)
Ryan da Silva Ramos, Josivan da Silva Costa, Rai Campos Silva, Glauber Vilhena da Costa, Alex Bruno Lobato Rodrigues, Érica de Menezes Rabelo, Raimundo Nonato Picanço Souto, Carlton Anthony Taft, Carlos Henrique Tomich de Paula da Silva, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos, Williams Jorge da Cruz Macêdo
Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening. Pharmaceuticals (Basel, Switzerland) 12 (1) (2019)
José A H M Bittencourt, Moysés F A Neto, Pedro Sousa Lacerda, Renata C V S Bittencourt, Rai C Silva, Cleison C Lobato, Luciane B Silva, Franco Henrique Andrade Leite, Juliana P Zuliani, Joaquín Maria Campos Rosa, Rosivaldo S Borges, Cleydson Breno Rodrigues Dos Santos
In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity. Molecules (Basel, Switzerland) 24 (8) (2019)
Vinícius de S Pinto, Janay S C Araújo, Rai C Silva, Glauber V da Costa, Jorddy Nevez Cruz, Moysés F De A Neto, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos, Franco H A Leite, Manoelito C Dos Santos Junior
In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations. Pharmaceuticals (Basel, Switzerland) 12 (1) (2019)
Rosivaldo S Borges, Ivanete C Palheta, Sirlene S B Ota, Roberto B Morais, Valéria A Barros, Ryan da Silva Ramos, Rai C Silva, Josivan da Silva Costa, Carlos H T P Silva, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism. Molecules (Basel, Switzerland) 24 (1) (2019)
Josiane V Cruz, Moysés F A Neto, Luciane B Silva, Ryan da S Ramos, Josivan da S Costa, Davi S B Brasil, Cleison C Lobato, Glauber V da Costa, José Adolfo H M Bittencourt, Carlos H T P da Silva, Franco H A Leite, Cleydson Breno Rodrigues Dos Santos
Identification of Novel Protein Kinase Receptor Type 2 Inhibitors Using Pharmacophore and Structure-Based Virtual Screening. Molecules (Basel, Switzerland) 23 (2) (2018)
Josivan da Silva Costa, Ryan da Silva Ramos, Karina da Silva Lopes Costa, Davi do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Elenilze Figueiredo Batista Ferreira, Rosivaldo Dos Santos Borges, Joaquín Maria Campos Rosa, Williams Jorge da Cruz Macêdo, Cleydson Breno Rodrigues Dos Santos
An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods. Molecules (Basel, Switzerland) 23 (11) (2018)
Mayara Amoras Teles Fujishima, Nayara Dos Santos Raulino da Silva, Ryan da Silva Ramos, Elenilze Figueiredo Batista Ferreira, Kelton Luís Belém Dos Santos, Carlos Henrique Tomich de Paula da Silva, Jocivania Oliveira da Silva, Joaquín Maria Campos Rosa, Cleydson Breno Rodrigues Dos Santos
An Antioxidant Potential, Quantum-Chemical and Molecular Docking Study of the Major Chemical Constituents Present in the Leaves of Curatella americana Linn. Pharmaceuticals (Basel, Switzerland) 11 (3) (2018)

Cleydson Breno Rodrigues Dos Santos.css-eqlu8i{font-size:small;padding-left:4px;} (Cleydson B R Dos Santos, C B R Santos, Cleydson B R Santos, Cleydson B R Santos)

Publication Activity (10 Years)

Top Topics

Top Venues

Cleydson Breno Rodrigues Dos Santos (Cleydson B R Dos Santos, C B R Santos, Cleydson B R Santos, Cleydson B R Santos)