Davide Trotti (D Trotti)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Topics

Amyotrophic Lateral Sclerosis

Tyrosine Kinase

Top Venues

Communications biology

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports 25 (5) (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports 25 (5) (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports 25 (5) (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports 25 (5) (2024)
Maria Elena Cicardi, V Kankate, S Sriramoji, Karthik Krishnamurthy, S S Markandaiah, B M Verdone, A Girdhar, A Nelson, L B Rivas, A Boehringer, Aaron R Haeusler, P Pasinelli, Lin Guo, Davide Trotti
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD. Communications biology 7 (1) (2024)
Maria Elena Cicardi, V Kankate, S Sriramoji, Karthik Krishnamurthy, S S Markandaiah, B M Verdone, A Girdhar, A Nelson, L B Rivas, A Boehringer, Aaron R Haeusler, P Pasinelli, Lin Guo, Davide Trotti
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD. Communications biology 7 (1) (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports 25 (5) (2024)
Maria Elena Cicardi, V Kankate, S Sriramoji, Karthik Krishnamurthy, S S Markandaiah, B M Verdone, A Girdhar, A Nelson, L B Rivas, A Boehringer, Aaron R Haeusler, P Pasinelli, Lin Guo, Davide Trotti
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD. Communications biology 7 (1) (2024)
Maria Elena Cicardi, V Kankate, S Sriramoji, Karthik Krishnamurthy, S S Markandaiah, B M Verdone, A Girdhar, A Nelson, L B Rivas, A Boehringer, Aaron R Haeusler, P Pasinelli, Lin Guo, Davide Trotti
The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD. Communications biology 7 (1) (2024)
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. eLife 12 (2024)
Andrew T Nelson, Maria Elena Cicardi, Shashirekha S Markandaiah, John Ys Han, Nancy J Philp, Emily Welebob, Aaron R Haeusler, Piera Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO reports (2024)
Francesco Antoniani, Marco Cimino, Laura Mediani, Jonathan Vinet, Enza M Verde, Valentina Secco, Alfred Yamoah, Priyanka Tripathi, Eleonora M A Aronica, Maria E Cicardi, Davide Trotti, Jared Sterneckert, Anand Goswami, Serena Carra
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia. Cell death discovery 9 (1) (2023)
Maria Elena Cicardi, J H Hallgren, D Mawrie, K Krishnamurthy, S S Markandaiah, A T Nelson, V Kankate, Eric N Anderson, P Pasinelli, Udai Bhan Pandey, Christine M Eischen, Davide Trotti
C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress. bioRxiv : the preprint server for biology (2023)
A T Nelson, Maria Elena Cicardi, S S Markandaiah, J Han, N Philp, E Welebob, Aaron R Haeusler, P Pasinelli, Giovanni Manfredi, Hibiki Kawamata, Davide Trotti
Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes. bioRxiv : the preprint server for biology (2023)
Maria Elena Cicardi, J H Hallgren, D Mawrie, K Krishnamurthy, S S Markandaiah, A T Nelson, V Kankate, Eric N Anderson, P Pasinelli, Udai Bhan Pandey, Christine M Eischen, Davide Trotti
C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress. bioRxiv : the preprint server for biology (2023)
Chiara Scopa, Samantha M Barnada, Maria E Cicardi, Mo Singer, Davide Trotti, Marco Trizzino
JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer's disease. Nature communications 14 (1) (2023)
Brigid K Jensen, Kevin J McAvoy, Nicolette M Heinsinger, Angelo C Lepore, Hristelina Ilieva, Aaron R Haeusler, Davide Trotti, Piera Pasinelli
Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice. Glia 70 (7) (2022)
Amanda M Gleixner, Brandie Morris Verdone, Charlton G Otte, Eric N Anderson, Nandini Ramesh, Olivia R Shapiro, Jenna R Gale, Jocelyn C Mauna, Jacob R Mann, Katie E Copley, Elizabeth D McKenna, Juan A Ortega, Maria Elena Cicardi, Evangelos Kiskinis, Julia Kofler, Udai Bhan Pandey, Davide Trotti, Christopher J Donnelly
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature communications 13 (1) (2022)
Andrew T Nelson, Davide Trotti
Altered Bioenergetics and Metabolic Homeostasis in Amyotrophic Lateral Sclerosis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 19 (4) (2022)
Maria Elena Cicardi, Lara Marrone, Mimoun Azzouz, Davide Trotti
Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis. The EMBO journal 40 (10) (2021)
Brigid K Jensen, Martin H Schuldi, Kevin McAvoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma, Aaron R Haeusler, Dieter Edbauer, Piera Pasinelli, Davide Trotti
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment. EMBO molecular medicine 12 (5) (2020)
Thomas Westergard, Kevin McAvoy, Katelyn Russell, Xinmei Wen, Yu Pang, Brandie Morris, Piera Pasinelli, Davide Trotti, Aaron R Haeusler
Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. EMBO molecular medicine 11 (2) (2019)
Roy Maimon, Ariel Ionescu, Avichai Bonnie, Sahar Sweetat, Shane Wald-Altman, Shani Inbar, Tal Gradus, Davide Trotti, Miguel Weil, Oded Behar, Eran Perlson
miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (24) (2018)