Donald E Spratt

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 21

Top Venues

International journal of molecular sciences

Future medicinal chemistry

Bioscience reports

Antioxidants (Basel, Switzerland)

Clark University

University of Waterloo (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Clark University

United States

Assistant Professor :: Carlson School of Chemistry & Biochemistry

Western University

Canada

Research Associate :: Biochemistry

Western University

Canada

Postdoctoral Fellow :: Biochemistry

Education History

University of Waterloo

Canada

PHD :: Chemistry

Mount Allison University

Canada

BSC :: Biochemistry

Publications

Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry 16 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry 16 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry 16 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry 16 (3) (2024)
Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry 16 (3) (2024)
Kelly L Waters, Donald E Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways. International journal of molecular sciences 25 (3) (2024)
Dipti Kanabar, Emma I Kane, Tejashri Chavan, Taylor M Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E Spratt, Aaron Muth
Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders. Future medicinal chemistry (2024)
Emma I Kane, Steven A Beasley, Johanna M Schafer, Justine E Bohl, Young Sun Lee, Kayla J Rich, Elizabeth F Bosia, Donald E Spratt
Redefining the catalytic HECT domain boundaries for the HECT E3 ubiquitin ligase family. Bioscience reports 42 (10) (2022)
Nicholas A Mathieu, Ermela Paparisto, Stephen D Barr, Donald E Spratt
HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response. Viruses 13 (6) (2021)
Qiuchen Zheng, Micheal T Kebede, Bethany Lee, Claire A Krasinski, Saadman Islam, Liliana A Wurfl, Merc M Kemeh, Valerie A Ivancic, Charles E Jakobsche, Donald E Spratt, Noel D Lazo
Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme. Antioxidants (Basel, Switzerland) 10 (9) (2021)
Emma I Kane, Donald E Spratt
Structural Insights into Ankyrin Repeat-Containing Proteins and Their Influence in Ubiquitylation. International journal of molecular sciences 22 (2) (2021)
Emma I Kane, Kelly L Waters, Donald E Spratt
Intersection of Redox Chemistry and Ubiquitylation: Post-Translational Modifications Required for Maintaining Cellular Homeostasis and Neuroprotection. Cells 10 (8) (2021)
Steven A Beasley, Chloe E Kellum, Rachel J Orlomoski, Feston Idrizi, Donald E Spratt
An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity. PloS one 15 (7) (2020)
Yaya Wang, Diana Argiles-Castillo, Emma I Kane, Anning Zhou, Donald E Spratt
HECT E3 ubiquitin ligases - emerging insights into their biological roles and disease relevance. Journal of cell science 133 (7) (2020)
Valerie A Ivancic, Claire A Krasinski, Qiuchen Zheng, Rebecca J Meservier, Donald E Spratt, Noel D Lazo
Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme. Bioscience reports 38 (6) (2018)
Steven A Beasley, Roela Bardhi, Donald E Spratt
1H, 13C, and 15N resonance assignments of the C-terminal lobe of the human HECT E3 ubiquitin ligase ITCH. Biomolecular NMR assignments 13 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Donald E Spratt