Fengzhi Li

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 7

Top Topics

Renal Cell Carcinoma

Top Venues

Journal of experimental & clinical cancer research : CR

International journal of molecular sciences

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Fengzhi Li, Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze, Xiaozhuo Liu, Pawel Kalinski, Dean G Tang
Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Yi Wang, Xiangli Zhang, Wenya Zhuang, Yanlei Yu, Xuan-Rong Sun, Hong Wang, Fengzhi Li, Qingyong Li
Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers. Molecules (Basel, Switzerland) 27 (12) (2022)
Xiang Ling, Wenjie Wu, Ieman A M Aljahdali, Jianqun Liao, Sreevidya Santha, Christos Fountzilas, Patrick M Boland, Fengzhi Li
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy. Clinical and translational medicine 12 (5) (2022)
Fengzhi Li, Ieman A M Aljahdali, Xiang Ling
Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein-Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases. International journal of molecular sciences 23 (11) (2022)
Fengzhi Li, Ieman A M Aljahdali, Renyuan Zhang, Kent L Nastiuk, John J Krolewski, Xiang Ling
Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma. Journal of experimental & clinical cancer research : CR 40 (1) (2021)
Sreevidya Santha, Xiang Ling, Ieman A M Aljahdali, Sailee S Rasam, Xue Wang, Jianqun Liao, Jue Wang, Christos Fountzilas, Qingyong Li, Jun Qu, Fengzhi Li
Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer. Cancers 12 (11) (2020)
Fengzhi Li, Ieman Aljahdali, Xiang Ling
Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study? Journal of experimental & clinical cancer research : CR 38 (1) (2019)