Haruhide Kimura

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Topics

Mass Spectrometry

Traumatic Brain Injury

Multidrug Resistant

Cerebrospinal Fluid

Top Venues

ACS chemical neuroscience

Pharmacology research & perspectives

Journal of sleep research

This page only lists publications with an associated author ORCID identifier.

Publications

Ryuji Yamada, Tatsuki Koike, Masanori Nakakariya, Haruhide Kimura
Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents. PloS one 19 (6) (2024)
Ryuji Yamada, Tatsuki Koike, Masanori Nakakariya, Haruhide Kimura
Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents. PloS one 19 (6) (2024)
Ryuji Yamada, Tatsuki Koike, Masanori Nakakariya, Haruhide Kimura
Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents. PloS one 19 (6) (2024)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Rebecca Evans, Haruhide Kimura, Masato Nakashima, Takashi Ishikawa, Hiroshi Yukitake, Motohisa Suzuki, James Hazel, Hélène Faessel, Jingtao Wu, Yaming Hang, Robert Alexander, Laura Rosen, Deborah S Hartman, Emiliangelo Ratti
Orexin 2 receptor-selective agonist danavorexton (TAK-925) promotes wakefulness in non-human primates and healthy individuals. Journal of sleep research (2023)
Rebecca Evans, Haruhide Kimura, Masato Nakashima, Takashi Ishikawa, Hiroshi Yukitake, Motohisa Suzuki, James Hazel, Hélène Faessel, Jingtao Wu, Yaming Hang, Robert Alexander, Laura Rosen, Deborah S Hartman, Emiliangelo Ratti
Orexin 2 receptor-selective agonist danavorexton (TAK-925) promotes wakefulness in non-human primates and healthy individuals. Journal of sleep research (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience (2023)
Naohiro Narita, Ryuji Yamada, Masaaki Kakehi, Haruhide Kimura
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry. ACS chemical neuroscience 14 (4) (2023)
Rina Baba, Satoru Matsuda, Ryota Maeda, Koji Murakami, Yukiko Yamamoto, Atsushi Nakatani, Haruhide Kimura
Investigating the Therapeutic Potential of LSD1 Enzyme Activity-Specific Inhibition by TAK-418 for Social and Memory Deficits in Rodent Disease Models. ACS chemical neuroscience 13 (3) (2022)
Rina Baba, Satoru Matsuda, Yuuichi Arakawa, Ryuji Yamada, Noriko Suzuki, Tatsuya Ando, Hideyuki Oki, Shigeru Igaki, Masaki Daini, Yasushi Hattori, Shigemitsu Matsumoto, Mitsuhiro Ito, Atsushi Nakatani, Haruhide Kimura
LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models. Science advances 7 (11) (2021)
Takao Mandai, Yuu Sako, Emi Kurimoto, Yuji Shimizu, Minoru Nakamura, Makoto Fushimi, Ryouta Maeda, Maki Miyamoto, Haruhide Kimura
T-495, a novel low cooperative M1 receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk. Pharmacology research & perspectives 8 (1) (2020)
Maiko Tanaka, Akiyoshi Kunugi, Atsushi Suzuki, Noriko Suzuki, Motohisa Suzuki, Haruhide Kimura
Preclinical characterization of AMPA receptor potentiator TAK-137 as a therapeutic drug for schizophrenia. Pharmacology research & perspectives 7 (3) (2019)
Kazunori Suzuki, Akina Harada, Hirobumi Suzuki, Clizia Capuani, Annarosa Ugolini, Mauro Corsi, Haruhide Kimura
Combined treatment with a selective PDE10A inhibitor TAK-063 and either haloperidol or olanzapine at subeffective doses produces potent antipsychotic-like effects without affecting plasma prolactin levels and cataleptic responses in rodents. Pharmacology research & perspectives 6 (1) (2018)
Kazunori Suzuki, Haruhide Kimura
TAK-063, a novel PDE10A inhibitor with balanced activation of direct and indirect pathways, provides a unique opportunity for the treatment of schizophrenia. CNS neuroscience & therapeutics 24 (7) (2018)
Hiroshi Yukitake, Masayuki Takizawa, Haruhide Kimura
Macrophage Migration Inhibitory Factor as an Emerging Drug Target to Regulate Antioxidant Response Element System. Oxidative medicine and cellular longevity 2017 (2017)