Hendrik Ungefroren

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 39

Top Topics

Transforming Growth Factor

Helicobacter Pylori

Peripheral Blood

Top Venues

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Hendrik Ungefroren, Julissa Reimann, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
RAC1b Collaborates with TAp73α-SMAD4 Signaling to Induce Biglycan Expression and Inhibit Basal and TGF-β-Driven Cell Motility in Human Pancreatic Cancer. Biomedicines 12 (1) (2024)
Hendrik Ungefroren, Julissa Reimann, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
RAC1b Collaborates with TAp73α-SMAD4 Signaling to Induce Biglycan Expression and Inhibit Basal and TGF-β-Driven Cell Motility in Human Pancreatic Cancer. Biomedicines 12 (1) (2024)
Hendrik Ungefroren, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Tobias Keck, Jens-Uwe Marquardt
Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma? Cancers 15 (3) (2023)
Rüdiger Braun, Olha Lapshyna, Jessica Watzelt, Maren Drenckhan, Axel Künstner, Benedikt Färber, Ahmed Ahmed Mohammed Hael, Louisa Bolm, Kim Christin Honselmann, Björn Konukiewitz, Darko Castven, Malte Spielmann, Sivahari Prasad Gorantla, Hauke Busch, Jens-Uwe Marquardt, Tobias Keck, Ulrich Friedrich Wellner, Hendrik Ungefroren
Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response. Cells 12 (4) (2023)
Rüdiger Braun, Olha Lapshyna, Jessica Watzelt, Maren Drenckhan, Axel Künstner, Benedikt Färber, Ahmed Ahmed Mohammed Hael, Louisa Bolm, Kim Christin Honselmann, Björn Konukiewitz, Darko Castven, Malte Spielmann, Sivahari Prasad Gorantla, Hauke Busch, Jens-Uwe Marquardt, Tobias Keck, Ulrich Friedrich Wellner, Hendrik Ungefroren
Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response. Cells 12 (4) (2023)
Rüdiger Braun, Hendrik Ungefroren
Preclinical Patient-Derived Culture Models for Personalized Treatment of Pancreatic Cancer: A Dream of the Future or Useful Practice? Cancers 15 (11) (2023)
Rüdiger Braun, Olha Lapshyna, Jessica Watzelt, Maren Drenckhan, Axel Künstner, Benedikt Färber, Ahmed Ahmed Mohammed Hael, Louisa Bolm, Kim Christin Honselmann, Björn Konukiewitz, Darko Castven, Malte Spielmann, Sivahari Prasad Gorantla, Hauke Busch, Jens-Uwe Marquardt, Tobias Keck, Ulrich Friedrich Wellner, Hendrik Ungefroren
Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response. Cells 12 (4) (2023)
Hendrik Ungefroren, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
TAp73 Inhibits EMT and Cell Migration in Pancreatic Cancer Cells through Promoting SMAD4 Expression and SMAD4-Dependent Inhibition of ERK Activation. Cancers 15 (15) (2023)
Hendrik Ungefroren, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Tobias Keck, Jens-Uwe Marquardt
Elucidation of the Role of SMAD4 in Epithelial-Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma? Cancers 15 (3) (2023)
Hendrik Ungefroren, Axel Künstner, Hauke Busch, Sören Franzenburg, Kim Luley, Fabrice Viol, Jörg Schrader, Björn Konukiewitz, Ulrich Friedrich Wellner, Sebastian M Meyhöfer, Tobias Keck, Jens-Uwe Marquardt, Hendrik Lehnert
Differential Effects of Somatostatin, Octreotide, and Lanreotide on Neuroendocrine Differentiation and Proliferation in Established and Primary NET Cell Lines: Possible Crosstalk with TGF-β Signaling. International journal of molecular sciences 23 (24) (2022)
Hendrik Ungefroren, Björn Konukiewitz, Ulrich Friedrich Wellner, Jörg Schrader, Tobias Keck
The Use of PDX1 DNA Methylation to Distinguish Two Subtypes of Pancreatic Neuroendocrine Neoplasms with Different Prognoses. Cancers 15 (1) (2022)
Hendrik Ungefroren, Isabel Thürling, Benedikt Färber, Tanja Kowalke, Tanja Fischer, Leonardo Vinícius Monteiro de Assis, Rüdiger Braun, Darko Castven, Henrik Oster, Björn Konukiewitz, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting. Cancers 14 (9) (2022)
Hendrik Ungefroren, Axel Künstner, Hauke Busch, Sören Franzenburg, Kim Luley, Fabrice Viol, Jörg Schrader, Björn Konukiewitz, Ulrich Friedrich Wellner, Sebastian M Meyhöfer, Tobias Keck, Jens-Uwe Marquardt, Hendrik Lehnert
Differential Effects of Somatostatin, Octreotide, and Lanreotide on Neuroendocrine Differentiation and Proliferation in Established and Primary NET Cell Lines: Possible Crosstalk with TGF-β Signaling. International journal of molecular sciences 23 (24) (2022)
Hendrik Ungefroren, Axel Künstner, Hauke Busch, Sören Franzenburg, Kim Luley, Fabrice Viol, Jörg Schrader, Björn Konukiewitz, Ulrich Friedrich Wellner, Sebastian M Meyhöfer, Tobias Keck, Jens-Uwe Marquardt, Hendrik Lehnert
Differential Effects of Somatostatin, Octreotide, and Lanreotide on Neuroendocrine Differentiation and Proliferation in Established and Primary NET Cell Lines: Possible Crosstalk with TGF-β Signaling. International journal of molecular sciences 23 (24) (2022)
Hendrik Ungefroren, Björn Konukiewitz, Ulrich Friedrich Wellner, Jörg Schrader, Tobias Keck
The Use of PDX1 DNA Methylation to Distinguish Two Subtypes of Pancreatic Neuroendocrine Neoplasms with Different Prognoses. Cancers 15 (1) (2022)
Hendrik Ungefroren, Axel Künstner, Hauke Busch, Sören Franzenburg, Kim Luley, Fabrice Viol, Jörg Schrader, Björn Konukiewitz, Ulrich Friedrich Wellner, Sebastian M Meyhöfer, Tobias Keck, Jens-Uwe Marquardt, Hendrik Lehnert
Differential Effects of Somatostatin, Octreotide, and Lanreotide on Neuroendocrine Differentiation and Proliferation in Established and Primary NET Cell Lines: Possible Crosstalk with TGF-β Signaling. International journal of molecular sciences 23 (24) (2022)
Hendrik Ungefroren, Björn Konukiewitz, Ulrich Friedrich Wellner, Jörg Schrader, Tobias Keck
The Use of PDX1 DNA Methylation to Distinguish Two Subtypes of Pancreatic Neuroendocrine Neoplasms with Different Prognoses. Cancers 15 (1) (2022)
Hendrik Ungefroren, Rüdiger Braun, Olha Lapshyna, Björn Konukiewitz, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Suppressive Role of ACVR1/ALK2 in Basal and TGFβ1-Induced Cell Migration in Pancreatic Ductal Adenocarcinoma Cells and Identification of a Self-Perpetuating Autoregulatory Loop Involving the Small GTPase RAC1b. Biomedicines 10 (10) (2022)
Hendrik Ungefroren
Autocrine TGF-β in Cancer: Review of the Literature and Caveats in Experimental Analysis. International journal of molecular sciences 22 (2) (2021)
Paula Marie Schmidtlein, Clara Volz, Alexander Hackel, Isabel Thürling, Darko Castven, Rüdiger Braun, Ulrich Friedrich Wellner, Björn Konukiewitz, Gabriela Riemekasten, Hendrik Lehnert, Jens-Uwe Marquardt, Hendrik Ungefroren
Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors. Cancers 13 (21) (2021)
Caroline Eiden, Hendrik Ungefroren
The Ratio of RAC1B to RAC1 Expression in Breast Cancer Cell Lines as a Determinant of Epithelial/Mesenchymal Differentiation and Migratory Potential. Cells 10 (2) (2021)
Paula M Schmidtlein, Clara Volz, Rüdiger Braun, Isabel Thürling, Olha Lapshyna, Ulrich Friedrich Wellner, Björn Konukiewitz, Hendrik Lehnert, Jens-Uwe Marquardt, Hendrik Ungefroren
A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity. Cancers 13 (18) (2021)
Hendrik Ungefroren, Jessica Christl, Caroline Eiden, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Autocrine TGFβ1 Opposes Exogenous TGFβ1-Induced Cell Migration and Growth Arrest through Sustainment of a Feed-Forward Loop Involving MEK-ERK Signaling. Cancers 13 (6) (2021)
Kim B Luley, Shauni B Biedermann, Axel Künstner, Hauke Busch, Sören Franzenburg, Jörg Schrader, Patricia Grabowski, Ulrich F Wellner, Tobias Keck, Georg Brabant, Sebastian M Schmid, Hendrik Lehnert, Hendrik Ungefroren
A Comprehensive Molecular Characterization of the Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1. Cancers 12 (3) (2020)
Hendrik Ungefroren, Hannah Otterbein, Ulrich Friedrich Wellner, Tobias Keck, Hendrik Lehnert, Jens-Uwe Marquardt
RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility. Cancers 12 (12) (2020)
Hendrik Ungefroren, Anuradha Kumarasinghe, Melina Musfeldt, Christian Fiedler, Hendrik Lehnert, Jens-Uwe Marquardt
RAC1B Induces SMAD7 via USP26 to Suppress TGFβ1-Dependent Cell Migration in Mesenchymal-Subtype Carcinoma Cells. Cancers 12 (6) (2020)
Ralf Hass, Juliane von der Ohe, Hendrik Ungefroren
Impact of the Tumor Microenvironment on Tumor Heterogeneity and Consequences for Cancer Cell Plasticity and Stemness. Cancers 12 (12) (2020)
Ralf Hass, Juliane von der Ohe, Hendrik Ungefroren
The Intimate Relationship Among EMT, MET and TME: A T(ransdifferentiation) E(nhancing) M(ix) to Be Exploited for Therapeutic Purposes. Cancers 12 (12) (2020)
Hendrik Ungefroren, Ulrich Friedrich Wellner, Tobias Keck, Hendrik Lehnert, Jens-Uwe Marquardt
The Small GTPase RAC1B: A Potent Negative Regulator of-and Useful Tool to Study-TGFβ Signaling. Cancers 12 (11) (2020)
Catharina Melzer, Ralf Hass, Hendrik Lehnert, Hendrik Ungefroren
RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression. Cells 8 (1) (2019)
Hendrik Ungefroren, Hannah Otterbein, Christian Fiedler, Koichiro Mihara, Morley D Hollenberg, Frank Gieseler, Hendrik Lehnert, David Witte
RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5. Cancers 11 (5) (2019)
Ralf Hass, Juliane von der Ohe, Hendrik Ungefroren
Potential Role of MSC/Cancer Cell Fusion and EMT for Breast Cancer Stem Cell Formation. Cancers 11 (10) (2019)
Hendrik Ungefroren
TGF-β Signaling in Cancer: Control by Negative Regulators and Crosstalk with Proinflammatory and Fibrogenic Pathways. Cancers 11 (3) (2019)
Hannah Otterbein, Koichiro Mihara, Morley D Hollenberg, Hendrik Lehnert, David Witte, Hendrik Ungefroren
RAC1B Suppresses TGF-β-Dependent Chemokinesis and Growth Inhibition through an Autoregulatory Feed-Forward Loop Involving PAR2 and ALK5. Cancers 11 (8) (2019)
Hannah Otterbein, Hendrik Lehnert, Hendrik Ungefroren
Negative Control of Cell Migration by Rac1b in Highly Metastatic Pancreatic Cancer Cells Is Mediated by Sequential Induction of Nonactivated Smad3 and Biglycan. Cancers 11 (12) (2019)
Catharina Melzer, Juliane von der Ohe, Hannah Otterbein, Hendrik Ungefroren, Ralf Hass
Changes in uPA, PAI-1, and TGF-β Production during Breast Cancer Cell Interaction with Human Mesenchymal Stroma/Stem-Like Cells (MSC). International journal of molecular sciences 20 (11) (2019)
Ayman Hyder, Sabrina Ehnert, Fred Fändrich, Hendrik Ungefroren
Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells. Stem cells international 2018 (2018)
Hendrik Ungefroren, David Witte, Hendrik Lehnert
The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer. Developmental dynamics : an official publication of the American Association of Anatomists 247 (3) (2017)
Catharina Melzer, Ralf Hass, Juliane von der Ohe, Hendrik Lehnert, Hendrik Ungefroren
The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma. Cell communication and signaling : CCS 15 (1) (2017)