Heng-Yu Fan (Hengyu Fan)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 35

Top Topics

Binding Protein

Intellectual Disability

Muscular Dystrophy

Top Venues

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Nature communications

Nucleic acids research

Development (Cambridge, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Hua Zhang, Yang Wang, Zhe-Wei Hu, Yun-Wen Wu, Nuo Chen, Yi-Min Zhu, Yuan-Song Yu, Heng-Yu Fan, Hua-Nan Wang
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (14) (2024)
Hua Zhang, Yang Wang, Zhe-Wei Hu, Yun-Wen Wu, Nuo Chen, Yi-Min Zhu, Yuan-Song Yu, Heng-Yu Fan, Hua-Nan Wang
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Hua Zhang, Yang Wang, Zhe-Wei Hu, Yun-Wen Wu, Nuo Chen, Yi-Min Zhu, Yuan-Song Yu, Heng-Yu Fan, Hua-Nan Wang
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (14) (2024)
Hua Zhang, Yang Wang, Zhe-Wei Hu, Yun-Wen Wu, Nuo Chen, Yi-Min Zhu, Yuan-Song Yu, Heng-Yu Fan, Hua-Nan Wang
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (14) (2024)
Hua Zhang, Yang Wang, Zhe-Wei Hu, Yun-Wen Wu, Nuo Chen, Yi-Min Zhu, Yuan-Song Yu, Heng-Yu Fan, Hua-Nan Wang
Zygotic Splicing Activation of the Transcriptome is a Crucial Aspect of Maternal-to-Zygotic Transition and Required for the Conversion from Totipotency to Pluripotency. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (14) (2024)
Lingli Huang, Wenqing Li, Xingxing Dai, Shuai Zhao, Bo Xu, Fengsong Wang, Ren-Tao Jin, Lihua Luo, Liming Wu, Xue Jiang, Yu Cheng, Jiaqi Zou, Caoling Xu, Xianhong Tong, Heng-Yu Fan, Han Zhao, Jianqiang Bao
Biallelic variants in MAD2L1BP ( p31 comet ) cause female infertility characterized by oocyte maturation arrest. eLife 12 (2023)
Lina Zhou, Shuai Wang, Wei Hu, Xiaoqian Liu, Lingdong Xu, Bolu Tong, Tongtong Zhang, Zhonghui Xue, Yixin Guo, Jing Zhao, Linrong Lu, Heng-Yu Fan, Weidong Han, Jian Chen, Wei J Chen, Lie Wang
T cell proliferation requires ribosomal maturation in nucleolar condensates dependent on DCAF13. The Journal of cell biology 222 (10) (2023)
Xing-Xing Dai, Shuai-Bo Pi, Long-Wen Zhao, Yun-Wen Wu, Jing-Ling Shen, Song-Ying Zhang, Qian-Qian Sha, Heng-Yu Fan
PABPN1 functions as a hub in the assembly of nuclear poly(A) domains that are essential for mouse oocyte development. Science advances 8 (43) (2022)
Yun-Wen Wu, Sen Li, Wei Zheng, Yan-Chu Li, Lu Chen, Yong Zhou, Zuo-Qi Deng, Ge Lin, Heng-Yu Fan, Qian-Qian Sha
Publisher Correction: Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging. Nature communications 13 (1) (2022)
Yun-Wen Wu, Sen Li, Wei Zheng, Yan-Chu Li, Lu Chen, Yong Zhou, Zuo-Qi Deng, Ge Lin, Heng-Yu Fan, Qian-Qian Sha
Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging. Nature communications 13 (1) (2022)
Hua Zhang, Jun-Chao Jiang, Yun-Wen Wu, Yuan-Song Yu, Hua-Nan Wang, Nai-Zheng Ding, Heng-Yu Fan
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development (Cambridge, England) 149 (19) (2022)
Yu-Ke Wu, Heng-Yu Fan
Revisiting ZAR proteins: the understudied regulator of female fertility and beyond. Cellular and molecular life sciences : CMLS 79 (2) (2022)
Jue Zhang, Shuai-Bo Pi, Nan Zhang, Jing Guo, Wei Zheng, Lizhi Leng, Ge Lin, Heng-Yu Fan
Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation. Nature communications 13 (1) (2022)
Yan Rong, Ye-Zhang Zhu, Jia-Li Yu, Yun-Wen Wu, Shu-Yan Ji, Yong Zhou, Yu Jiang, Jin Jin, Heng-Yu Fan, Li Shen, Qian-Qian Sha
USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation. Nucleic acids research 50 (10) (2022)
Long-Wen Zhao, Ye-Zhang Zhu, Yun-Wen Wu, Shuai-Bo Pi, Li Shen, Heng-Yu Fan
Nuclear poly(A) binding protein 1 (PABPN1) mediates zygotic genome activation-dependent maternal mRNA clearance during mouse early embryonic development. Nucleic acids research 50 (1) (2022)
Lu Chen, Wen-Jing Wang, Qiang Liu, Yu-Ke Wu, Yun-Wen Wu, Yu Jiang, Xiu-Quan Liao, Fei Huang, Yang Li, Li Shen, Chao Yu, Song-Ying Zhang, Li-Ying Yan, Jie Qiao, Qian-Qian Sha, Heng-Yu Fan
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells. Nucleic acids research 50 (19) (2022)
Yerong Ma, Weijie Yang, Peipei Ren, Xiang Li, Jiamin Jin, Yongdong Dai, Yibin Pan, Lingling Jiang, Heng-Yu Fan, Yin-Li Zhang, Song-Ying Zhang
Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes. Molecular human reproduction 27 (6) (2022)
Xing-Xing Dai, Yu Jiang, Jia-Hui Gu, Zhi-Yan Jiang, Yun-Wen Wu, Chao Yu, Hao Yin, Jue Zhang, Qing-Hua Shi, Li Shen, Qian-Qian Sha, Heng-Yu Fan
The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (10) (2021)
Long-Wen Zhao, Heng-Yu Fan
Revisiting poly(A)-binding proteins: Multifaceted regulators during gametogenesis and early embryogenesis. BioEssays : news and reviews in molecular, cellular and developmental biology 43 (6) (2021)
Jun-Chao Jiang, Hua Zhang, Lan-Rui Cao, Xing-Xing Dai, Long-Wen Zhao, Hong-Bin Liu, Heng-Yu Fan
Oocyte meiosis-coupled poly(A) polymerase α phosphorylation and activation trigger maternal mRNA translation in mice. Nucleic acids research 49 (10) (2021)
Yin-Li Zhang, Wei Zheng, Peipei Ren, Huiling Hu, Xiaomei Tong, Shuo-Ping Zhang, Xiang Li, Haichao Wang, Jun-Chao Jiang, Jiamin Jin, Weijie Yang, Lanrui Cao, Yuanlin He, Yerong Ma, Yingyi Zhang, Yifan Gu, Liang Hu, Keli Luo, Fei Gong, Guang-Xiu Lu, Ge Lin, Heng-Yu Fan, Song-Ying Zhang
Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation. EMBO molecular medicine 13 (12) (2021)
Jing Zhao, Ke Yao, Hua Yu, Ling Zhang, Yuyan Xu, Lang Chen, Zhen Sun, Yuqing Zhu, Cheng Zhang, Yuli Qian, Shuyan Ji, Hongru Pan, Min Zhang, Jie Chen, Cristina Correia, Taylor Weiskittel, Da-Wei Lin, Yu-Zheng Zhao, Sriram Chandrasekaran, Xudong Fu, Dan Zhang, Heng-Yu Fan, Wei Xie, Hu Li, Ze-Ping Hu, Jin Zhang
Metabolic remodelling during early mouse embryo development. Nature metabolism 3 (10) (2021)
Long-Wen Zhao, Ye-Zhang Zhu, Hao Chen, Yun-Wen Wu, Shuai-Bo Pi, Lu Chen, Li Shen, Heng-Yu Fan
PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal-to-zygotic transition. EMBO reports 21 (8) (2020)
Yu Jiang, Hui-Ying Zhang, Zhen Lin, Ye-Zhang Zhu, Chao Yu, Qian-Qian Sha, Ming-Han Tong, Li Shen, Heng-Yu Fan
CXXC finger protein 1-mediated histone H3 lysine-4 trimethylation is essential for proper meiotic crossover formation in mice. Development (Cambridge, England) 147 (6) (2020)
Qian-Qian Sha, Wei Zheng, Yun-Wen Wu, Sen Li, Lei Guo, Shuoping Zhang, Ge Lin, Xiang-Hong Ou, Heng-Yu Fan
Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans. Nature communications 11 (1) (2020)
Jue Zhang, Yin-Li Zhang, Long-Wen Zhao, Shuai-Bo Pi, Song-Ying Zhang, Chao Tong, Heng-Yu Fan
The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation. Cellular and molecular life sciences : CMLS 77 (11) (2019)
Qian-Qian Sha, Yu Jiang, Chao Yu, Yunlong Xiang, Xing-Xing Dai, Jun-Chao Jiang, Xiang-Hong Ou, Heng-Yu Fan
CFP1-dependent histone H3K4 trimethylation in murine oocytes facilitates ovarian follicle recruitment and ovulation in a cell-nonautonomous manner. Cellular and molecular life sciences : CMLS 77 (15) (2019)
Yang Liu, Long-Wen Zhao, Jing-Ling Shen, Heng-Yu Fan, Yan Jin
Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development. Scientific reports 9 (1) (2019)
Qian-Qian Sha, Jia-Li Yu, Jing-Xin Guo, Xing-Xing Dai, Jun-Chao Jiang, Yin-Li Zhang, Chao Yu, Shu-Yan Ji, Yu Jiang, Song-Ying Zhang, Li Shen, Xiang-Hong Ou, Heng-Yu Fan
CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte. The EMBO journal 37 (24) (2018)
Yin-Li Zhang, Long-Wen Zhao, Jue Zhang, Rongrong Le, Shu-Yan Ji, Chuan Chen, Yawei Gao, Dali Li, Shaorong Gao, Heng-Yu Fan
DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. The EMBO journal 37 (18) (2018)
Xiao-Man Liu, Ming-Qi Yan, Shu-Yan Ji, Qian-Qian Sha, Tao Huang, Han Zhao, Hong-Bin Liu, Heng-Yu Fan, Zi-Jiang Chen
Loss of oocyte Rps26 in mice arrests oocyte growth and causes premature ovarian failure. Cell death & disease 9 (12) (2018)
Qian-Qian Sha, Xing-Xing Dai, Jun-Chao Jiang, Chao Yu, Yu Jiang, Junping Liu, Xiang-Hong Ou, Song-Ying Zhang, Heng-Yu Fan
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes. Nature communications 9 (1) (2018)
Jue Zhang, Yin-Li Zhang, Long-Wen Zhao, Jing-Xin Guo, Jia-Li Yu, Shu-Yan Ji, Lan-Rui Cao, Song-Ying Zhang, Li Shen, Xiang-Hong Ou, Heng-Yu Fan
Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell death and differentiation 26 (7) (2018)
Yi-Wen Xu, Lan-Rui Cao, Min Wang, Ying Xu, Xin Wu, Junping Liu, Chao Tong, Heng-Yu Fan
Maternal DCAF2 is crucial for maintenance of genome stability during the first cell cycle in mice. Journal of cell science 130 (19) (2017)
Qian-Qian Sha, Xing-Xing Dai, Yujiao Dang, Fuchou Tang, Junping Liu, Yin-Li Zhang, Heng-Yu Fan
A MAPK cascade couples maternal mRNA translation and degradation to meiotic cell cycle progression in mouse oocytes. Development (Cambridge, England) 144 (3) (2016)