Hiroaki Okamoto

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 47

Top Venues

Viruses

Clinical journal of gastroenterology

Journal of virology

Hepatology research : the official journal of the Japan Society of Hepatology

Jichi Medical University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Jichi Medical University

Japan

Professor :: Department of Infection and Immunity, Division of Virology

Publications

Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology 17 (4) (2024)
Putu Prathiwi Primadharsini, Masaharu Takahashi, Tsutomu Nishizawa, Yukihiro Sato, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto
The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines. Viruses 16 (6) (2024)
Tatsuo Kanda, Tian-Cheng Li, Masaharu Takahashi, Shigeo Nagashima, Putu Prathiwi Primadharsini, Satoshi Kunita, Reina Sasaki-Tanaka, Jun Inoue, Atsunori Tsuchiya, Shingo Nakamoto, Ryuzo Abe, Keiichi Fujiwara, Osamu Yokosuka, Ryosuke Suzuki, Koji Ishii, Hiroshi Yotsuyanagi, Hiroaki Okamoto, null null
Recent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection. Hepatology research : the official journal of the Japan Society of Hepatology (2024)
Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology (2024)
Tatsuo Kanda, Tian-Cheng Li, Masaharu Takahashi, Shigeo Nagashima, Putu Prathiwi Primadharsini, Satoshi Kunita, Reina Sasaki-Tanaka, Jun Inoue, Atsunori Tsuchiya, Shingo Nakamoto, Ryuzo Abe, Keiichi Fujiwara, Osamu Yokosuka, Ryosuke Suzuki, Koji Ishii, Hiroshi Yotsuyanagi, Hiroaki Okamoto, null null
Recent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection. Hepatology research : the official journal of the Japan Society of Hepatology 54 (8) (2024)
Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology (2024)
Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Correction: Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology (2024)
Putu Prathiwi Primadharsini, Masaharu Takahashi, Tsutomu Nishizawa, Yukihiro Sato, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto
The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines. Viruses 16 (6) (2024)
Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology 17 (4) (2024)
Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Correction: Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology (2024)
Putu Prathiwi Primadharsini, Masaharu Takahashi, Tsutomu Nishizawa, Yukihiro Sato, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto
The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines. Viruses 16 (6) (2024)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. Viruses 15 (4) (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology 97 (2) (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology 97 (2) (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology 97 (2) (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology 97 (2) (2023)
Hideyuki Suzuki, Ken Sato, Jirou Takezawa, Shoji Yamada, Masashi Namikawa, Hiroaki Okamoto
Successful prolonged treatment with sofosbuvir/velpatasvir for a hepatitis C patient with decompensated cirrhosis and treatment failure after 12-week therapy. Clinical journal of gastroenterology (2023)
Tatsuo Kanda, Reina Sasaki-Tanaka, Koji Ishii, Ryosuke Suzuki, Jun Inoue, Atsunori Tsuchiya, Shingo Nakamoto, Ryuzo Abe, Keiichi Fujiwara, Osamu Yokosuka, Tian-Cheng Li, Satoshi Kunita, Hiroshi Yotsuyanagi, Hiroaki Okamoto, null null
Recent advances in hepatitis A virus (HAV) research and clinical practice guidelines for HAV infection in Japan. Hepatology research : the official journal of the Japan Society of Hepatology (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology 97 (2) (2023)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. Viruses 15 (4) (2023)
Reina Sasaki-Tanaka, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Asuka Hirai-Yuki, Hiroaki Okamoto, Tatsuo Kanda
Masitinib Inhibits Hepatitis A Virus Replication. International journal of molecular sciences 24 (11) (2023)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. Viruses 15 (4) (2023)
Shigeo Nagashima, Putu Prathiwi Primadharsini, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform. Journal of virology (2023)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Takashi Nishiyama, Hiroaki Okamoto
Three Distinct Reporter Systems of Hepatitis E Virus and Their Utility as Drug Screening Platforms. Viruses 15 (10) (2023)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. Viruses 15 (4) (2023)
Yuichi Yoshida, Asami Ito, Hisashi Eto, Akiko Suzuki, Tamami Abe, Kei Endo, Keisuke Kakisaka, Takayoshi Oikawa, Hidekatsu Kuroda, Akio Miyasaka, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto
Seroprevalence and incidence of hepatitis E virus infection in the general population of Iwate Prefecture, Japan: A retrospective cohort study. Hepatology research : the official journal of the Japan Society of Hepatology (2023)
Reina Sasaki-Tanaka, Ryota Masuzaki, Hiroaki Okamoto, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Tatsuo Kanda
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication. Journal of virology (2023)
Masaharu Takahashi, Satoshi Kunita, Tsutomu Nishizawa, Hiroshi Ohnishi, Putu Prathiwi Primadharsini, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto
Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 2021. Viruses 15 (7) (2023)
Davaalkham Dambadarjaa, Otgonbayar Radnaa, Ser-Od Khuyag, Oyu-Erdene Shagdarsuren, Uranbaigali Enkhbayar, Yerkyebulan Mukhtar, Enkh-Oyun Tsogzolbaatar, Gunchmaa Nyam, Shatar Shaarii, Pramil N Singh, Masaharu Takahashi, Bira Namdag, Hiroaki Okamoto
Hepatitis B, C, and D Virus Infection among Population Aged 10-64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study. Vaccines 10 (11) (2022)
Reina Sasaki-Tanaka, Kalyan C Nagulapalli Venkata, Hiroaki Okamoto, Mitsuhiko Moriyama, Tatsuo Kanda
Evaluation of Potential Anti-Hepatitis A Virus 3C Protease Inhibitors Using Molecular Docking. International journal of molecular sciences 23 (11) (2022)
Reina Sasaki-Tanaka, Toshikatsu Shibata, Hiroaki Okamoto, Mitsuhiko Moriyama, Tatsuo Kanda
Favipiravir Inhibits Hepatitis A Virus Infection in Human Hepatocytes. International journal of molecular sciences 23 (5) (2022)
Satoshi Takakusagi, Hitoshi Takagi, Yuichi Yamazaki, Takashi Kosone, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Chronic hepatitis E in an elderly immunocompetent patient who achieved a sustained virologic response with ribavirin treatment. Clinical journal of gastroenterology (2022)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Development of Recombinant Infectious Hepatitis E Virus Harboring the nanoKAZ Gene and Its Application in Drug Screening. Journal of virology 96 (6) (2022)
Reina Sasaki-Tanaka, Toshikatsu Shibata, Mitsuhiko Moriyama, Hiroaki Okamoto, Hirofumi Kogure, Tatsuo Kanda
Amantadine and Rimantadine Inhibit Hepatitis A Virus Replication through the Induction of Autophagy. Journal of virology 96 (18) (2022)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin. Viruses 14 (11) (2022)
Tsutomu Nishizawa, null Mulyanto, Yumi Hatano, Kazumoto Murata, Hiroaki Okamoto
Complete Genome Sequences of Two Rat Pegivirus Strains in Indonesia. Microbiology resource announcements 10 (11) (2021)
Takashi Nishiyama, Koji Umezawa, Kentaro Yamada, Masaharu Takahashi, Satoshi Kunita, null Mulyanto, Isao Kii, Hiroaki Okamoto
The Capsid (ORF2) Protein of Hepatitis E Virus in Feces Is C-Terminally Truncated. Pathogens (Basel, Switzerland) 11 (1) (2021)
Satoshi Takakusagi, Hitoshi Takagi, Yozo Yokoyama, Kazuko Kizawa, Kyoko Marubashi, Takashi Kosone, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto
Spontaneous reactivation of hepatitis B virus with a frameshift mutation in the precore region in an elderly hepatitis B virus carrier with lifestyle-related diseases. Clinical journal of gastroenterology 14 (4) (2021)
Putu Prathiwi Primadharsini, Shigeo Nagashima, Hiroaki Okamoto
Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus. Viruses 13 (5) (2021)
Tatsuo Kanda, Reina Sasaki-Tanaka, Ryota Masuzaki, Naoki Matsumoto, Hiroaki Okamoto, Mitsuhiko Moriyama
Knockdown of Mitogen-Activated Protein Kinase Kinase 3 Negatively Regulates Hepatitis A Virus Replication. International journal of molecular sciences 22 (14) (2021)
Naoto Sato, Shunji Watanabe, Kouichi Miura, Naoki Morimoto, Yoshinari Takaoka, Hiroaki Nomoto, Norio Isoda, Shigeo Nagashima, Masaharu Takahashi, Hiroaki Okamoto, Hironori Yamamoto
Clinical and virologic features of hepatitis E virus infection at a university hospital in Japan between 2000 and 2019. Journal of medical virology (2020)
Chikako Yamamoto, Ko Ko, Shintaro Nagashima, Takayuki Harakawa, Toshiko Fujii, Masayuki Ohisa, Keiko Katayama, Kazuaki Takahashi, Hiroaki Okamoto, Junko Tanaka
Very low prevalence of anti-HAV in Japan: high potential for future outbreak. Scientific reports 9 (1) (2019)
Putu Prathiwi Primadharsini, null Mulyanto, I Dewa Nyoman Wibawa, Joko Anggoro, Tsutomu Nishizawa, Masaharu Takahashi, Suljid Jirintai, Hiroaki Okamoto
The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia. Archives of virology 163 (5) (2018)
Bira Tsatsralt-Od, Putu Prathiwi Primadharsini, Tsutomu Nishizawa, Hiroshi Ohnishi, Shigeo Nagashima, Masaharu Takahashi, Suljid Jirintai, Dulmaa Nyamkhuu, Hiroaki Okamoto
Distinct changing profiles of hepatitis A and E virus infection among patients with acute hepatitis in Mongolia: The first report of the full genome sequence of a novel genotype 1 hepatitis E virus strain. Journal of medical virology 90 (1) (2017)
Shigeo Nagashima, Masaharu Takahashi, Tominari Kobayashi, null null, Tsutomu Nishizawa, Takashi Nishiyama, Putu Prathiwi Primadharsini, Hiroaki Okamoto
Characterization of the Quasi-Enveloped Hepatitis E Virus Particles Released by the Cellular Exosomal Pathway. Journal of virology 91 (22) (2017)
Yasuko Yamaguchi, Hitoshi Takagi, Yuhei Suzuki, Kyoko Maruhashi, Takashi Kosone, Satoru Kakizaki, Ken Sato, Masanobu Yamada, Shigeo Nagashima, Masaharu Takahashi, Hiroaki Okamoto
Autochthonous sporadic acute hepatitis E caused by two distinct subgenotype 3b hepatitis E virus strains with only 90% nucleotide identity. Clinical journal of gastroenterology 10 (2) (2017)
Masaharu Takahashi, Tominari Kobayashi, null Tanggis, Suljid Jirintai, null Mulyanto, Shigeo Nagashima, Tsutomu Nishizawa, Satoshi Kunita, Hiroaki Okamoto
Production of monoclonal antibodies against the ORF3 protein of rat hepatitis E virus (HEV) and demonstration of the incorporation of the ORF3 protein into enveloped rat HEV particles. Archives of virology 161 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hiroaki Okamoto