Holger Heine

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 21

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Pharmaceuticals (Basel, Switzerland)

ChemMedChem

Angewandte Chemie (International ed. in English)

Forschungszentrum Borstel Leibniz - Leibniz Lungenzentrum

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Forschungszentrum Borstel Leibniz - Leibniz Lungenzentrum Jul 01 1999

Germany

Head, Division of Innate Immunity :: Priority Area Asthma and Allergy

Publications

Sebastian Strobl, Daniele Zucchetta, Tomáš Vašíček, Alessandro Monti, Alessandro Ruda, Göran Widmalm, Holger Heine, Alla Zamyatina
Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4-specific LPS Mimetics with Picomolar Potency. Angewandte Chemie (International ed. in English) (2024)
Alessio Borio, Aurora Holgado, Christina Passegger, Herbert Strobl, Rudi Beyaert, Holger Heine, Alla Zamyatina
Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids. Molecules (Basel, Switzerland) 28 (16) (2023)
Holger Heine, Alla Zamyatina
Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics. Pharmaceuticals (Basel, Switzerland) 16 (1) (2022)
Holger Heine, Alla Zamyatina
Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics. Pharmaceuticals (Basel, Switzerland) 16 (1) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Sebastian Strobl, Karin Hofbauer, Holger Heine, Alla Zamyatina
Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (35) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Holger Heine, Alla Zamyatina
Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics. Pharmaceuticals (Basel, Switzerland) 16 (1) (2022)
Holger Heine, Alla Zamyatina
Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics. Pharmaceuticals (Basel, Switzerland) 16 (1) (2022)
Zhongjie Wang, Eva-Maria L Minarsch, Susanne Kublik, Holger Heine, Michael Schloter, Baerbel U Foesel
Complete Genome Sequence of Lactococcus lactis subsp. lactis G121, an Isolate with Allergy-Protective Features Derived from a Farming Environment. Microbiology resource announcements 9 (41) (2020)
Franziska Herster, Zsofia Bittner, Nathan K Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N R Weber
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis. Nature communications 11 (1) (2020)
Iwona Komaniecka, Katarzyna Susniak, Adam Choma, Holger Heine, Otto Holst
The Lipid A from the Lipopolysaccharide of the Phototrophic Bacterium Rhodomicrobium vannielii ATCC 17100 Revisited. International journal of molecular sciences 22 (1) (2020)
Isabel Freund, Daniel K Buhl, Sébastien Boutin, Annika Kotter, Florian Pichot, Virginie Marchand, Tim Vierbuchen, Holger Heine, Yuri Motorin, Mark Helm, Alexander H Dalpke, Tatjana Eigenbrod
2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms. RNA (New York, N.Y.) 25 (7) (2019)
Judith Bossen, Karin Uliczka, Line Steen, Roxana Pfefferkorn, Mandy Mong-Quyen Mai, Lia Burkhardt, Michael Spohn, Iris Bruchhaus, Christine Fink, Holger Heine, Thomas Roeder
An EGFR-Induced Drosophila Lung Tumor Model Identifies Alternative Combination Treatments. Molecular cancer therapeutics 18 (9) (2019)
Florian Adanitsch, Jianjin Shi, Feng Shao, Rudi Beyaert, Holger Heine, Alla Zamyatina
Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics. Chemical science 9 (16) (2018)
Tim Vierbuchen, Karina Stein, Holger Heine
RNA is taking its Toll: Impact of RNA-specific Toll-like receptors on health and disease. Allergy 74 (2) (2018)
Alessio Borio, Aurora Holgado, Jose Antonio Garate, Rudi Beyaert, Holger Heine, Alla Zamyatina
Disaccharide-Based Anionic Amphiphiles as Potent Inhibitors of Lipopolysaccharide-Induced Inflammation. ChemMedChem 13 (21) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Holger Heine