Jose Javier Ruiz-Pernía (J Javier Ruiz-Pernía, José Javier Ruiz-Pernía)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 20

Top Venues

Chemical science

Journal of chemical information and modeling

Nature communications

Angewandte Chemie (International ed. in English)

Universitat de València

Universitat de València (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universitat de València Sep 05 2017

Spain

Assistant Professor :: Química Física

Universitat Jaume I Nov 16 2015 - Sep 04 2017

Spain

Research Officer :: Departament de Química Física y Analítica

Universidade Estadual Paulista Julio de Mesquita Filho Instituto de Química Jan 01 2014 - Nov 15 2015

Brazil

Postdoctoral Researcher. :: Departamento de Quimica

Universitat Jaume I Jan 01 2013 - Feb 28 2014

Spain

Postdoctoral Researcher. :: Departament de Química Física y Analítica

Universitat Jaume I Jan 01 2010 - Dec 31 2012

Spain

Contratado Juan de la Cierva. :: Departament de Química Física y Analítica

University of Bath Department of Chemistry Jul 16 2007 - Nov 30 2009

United Kingdom

Officer Researcher. Postdoc. :: Department of Chemistry

Education History

Universitat de València Jan 01 2003 - Jun 08 2007

Spain

PHD :: Departament de Química Física

Publications

Johanna Schillings, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Pomotrelvir and Nirmatrelvir Binding and Reactivity with SARS-CoV-2 Main Protease: Implications for Resistance Mechanisms from Computations. Angewandte Chemie (International ed. in English) (2024)
Kirill Zinovjev, Paul Guénon, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Damien Laage, Iñaki Tuñón
Activation and friction in enzymatic loop opening and closing dynamics. Nature communications 15 (1) (2024)
José Luis Velázquez-Libera, Julio Caballero, Jans H Alzate-Morales, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Understanding the Interactions of Ubiquitin-Specific Protease 7 with Its Substrates through Molecular Dynamics Simulations: Insights into the Role of Its C-Terminal Domains in Substrate Recognition. Journal of chemical information and modeling 64 (10) (2024)
José Luis Velázquez-Libera, Julio Caballero, Jans H Alzate-Morales, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Understanding the Interactions of Ubiquitin-Specific Protease 7 with Its Substrates through Molecular Dynamics Simulations: Insights into the Role of Its C-Terminal Domains in Substrate Recognition. Journal of chemical information and modeling 64 (10) (2024)
Kirill Zinovjev, Paul Guénon, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Damien Laage, Iñaki Tuñón
Activation and friction in enzymatic loop opening and closing dynamics. Nature communications 15 (1) (2024)
José Luis Velázquez-Libera, Julio Caballero, Jans H Alzate-Morales, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Understanding the Interactions of Ubiquitin-Specific Protease 7 with Its Substrates through Molecular Dynamics Simulations: Insights into the Role of Its C-Terminal Domains in Substrate Recognition. Journal of chemical information and modeling (2024)
Kirill Zinovjev, Paul Guénon, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Damien Laage, Iñaki Tuñón
Activation and friction in enzymatic loop opening and closing dynamics. Nature communications 15 (1) (2024)
Adrián García-Martínez, Kirill Zinovjev, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Conformational Changes and ATP Hydrolysis in Zika Helicase: The Molecular Basis of a Biomolecular Motor Unveiled by Multiscale Simulations. Journal of the American Chemical Society (2023)
Carlos Alberto Ramos-Guzmán, Milorad Andjelkovic, Kirill Zinovjev, Jose Javier Ruiz-Pernía, Iñaki Tuñón
The impact of SARS-CoV-2 3CL protease mutations on nirmatrelvir inhibitory efficiency. Computational insights into potential resistance mechanisms. Chemical science 14 (10) (2023)
Carlos Alberto Ramos-Guzmán, Milorad Andjelkovic, Kirill Zinovjev, Jose Javier Ruiz-Pernía, Iñaki Tuñón
The impact of SARS-CoV-2 3CL protease mutations on nirmatrelvir inhibitory efficiency. Computational insights into potential resistance mechanisms. Chemical science 14 (10) (2023)
Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Kirill Zinovjev, Iñaki Tuñón
Unveiling the Mechanistic Singularities of Caspases: A Computational Analysis of the Reaction Mechanism in Human Caspase-1. ACS catalysis 13 (7) (2023)
Rafael García-Meseguer, Enrique Ortí, Iñaki Tuñón, Jose Javier Ruiz-Pernía, Juan Aragó
Insights into the Enhancement of the Poly(ethylene terephthalate) Degradation by FAST-PETase from Computational Modeling. Journal of the American Chemical Society (2023)
Milorad Andjelkovic, Kirill Zinovjev, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Elucidation of the Active Form and Reaction Mechanism in Human Asparaginase Type III Using Multiscale Simulations. Journal of chemical information and modeling (2023)
Carlos A Ramos-Guzmán, José Luis Velázquez-Libera, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Testing Affordable Strategies for the Computational Study of Reactivity in Cysteine Proteases: The Case of SARS-CoV-2 3CL Protease Inhibition. Journal of chemical theory and computation 18 (6) (2022)
Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Inhibition Mechanism of SARS-CoV-2 Main Protease with Ketone-Based Inhibitors Unveiled by Multiscale Simulations: Insights for Improved Designs*. Angewandte Chemie (International ed. in English) 60 (49) (2021)
Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Iñaki Tuñón
Computational simulations on the binding and reactivity of a nitrile inhibitor of the SARS-CoV-2 main protease. Chemical communications (Cambridge, England) 57 (72) (2021)
Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz-Pernía, Iñaki Tuñón
A microscopic description of SARS-CoV-2 main protease inhibition with Michael acceptors. Strategies for improving inhibitor design. Chemical science 12 (10) (2021)
José Navarro-Sánchez, Neyvis Almora-Barrios, Belén Lerma-Berlanga, Jose Javier Ruiz-Pernía, Victor A Lorenz-Fonfria, Iñaki Tuñón, Carlos Martí-Gastaldo
Translocation of enzymes into a mesoporous MOF for enhanced catalytic activity under extreme conditions. Chemical science 10 (14) (2019)
Maite Roca, Jose Javier Ruiz-Pernía, Raquel Castillo, Mónica Oliva, Vicent Moliner
Temperature dependence of dynamic, tunnelling and kinetic isotope effects in formate dehydrogenase. Physical chemistry chemical physics : PCCP 20 (40) (2018)
Jose Javier Ruiz-Pernía, Enas Behiry, Louis Y P Luk, Edric Joel Loveridge, Iñaki Tuñón, Vicent Moliner, Rudolf K Allemann
Minimization of dynamic effects in the evolution of dihydrofolate reductase. Chemical science 7 (5) (2016)

Jose Javier Ruiz-Pernía.css-eqlu8i{font-size:small;padding-left:4px;} (J Javier Ruiz-Pernía, José Javier Ruiz-Pernía)

Publication Activity (10 Years)

Top Topics

Top Venues

Jose Javier Ruiz-Pernía (J Javier Ruiz-Pernía, José Javier Ruiz-Pernía)