John M Mariadason (John Mariadason)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Topics

Transcription Factor

Histone Deacetylase

Endoplasmic Reticulum

Top Venues

Communications biology

Cell death & disease

Cell death discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Laura J Jenkins, Ian Y Luk, Fiona Chionh, Tao Tan, Kristen Needham, Jamieson Ayton, Camilla M Reehorst, Natalia Vukelic, Oliver M Sieber, Dmitri Mouradov, Peter Gibbs, David S Williams, Niall C Tebbutt, Jayesh Desai, Frédéric Hollande, Amardeep S Dhillon, Erinna F Lee, Delphine Merino, Walter Douglas Fairlie, John M Mariadason
BCL-X L inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF V600E colorectal cancer. Cell death & disease 15 (3) (2024)
Laura J Jenkins, Ian Y Luk, Fiona Chionh, Tao Tan, Kristen Needham, Jamieson Ayton, Camilla M Reehorst, Natalia Vukelic, Oliver M Sieber, Dmitri Mouradov, Peter Gibbs, David S Williams, Niall C Tebbutt, Jayesh Desai, Frédéric Hollande, Amardeep S Dhillon, Erinna F Lee, Delphine Merino, Walter Douglas Fairlie, John M Mariadason
BCL-X L inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF V600E colorectal cancer. Cell death & disease 15 (3) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
David K Lau, Jack P Collin, John M Mariadason
Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer. Biomedicines 12 (5) (2024)
David K Lau, Jack P Collin, John M Mariadason
Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer. Biomedicines 12 (5) (2024)
Laura J Jenkins, Ian Y Luk, Fiona Chionh, Tao Tan, Kristen Needham, Jamieson Ayton, Camilla M Reehorst, Natalia Vukelic, Oliver M Sieber, Dmitri Mouradov, Peter Gibbs, David S Williams, Niall C Tebbutt, Jayesh Desai, Frédéric Hollande, Amardeep S Dhillon, Erinna F Lee, Delphine Merino, Walter Douglas Fairlie, John M Mariadason
BCL-X L inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF V600E colorectal cancer. Cell death & disease 15 (3) (2024)
Sharon Tran, Juliani Juliani, Tiffany J Harris, Marco Evangelista, Julian Ratcliffe, Sarah L Ellis, David Baloyan, Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins, Sonia Ghilas, Marina H Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C Lee, Peter De Cruz, Kinga Duszyc, Paul A Gleeson, Benjamin T Kile, Lisa A Mielke, Alpha S Yap, John M Mariadason, Walter Douglas Fairlie, Erinna F Lee
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking. Communications biology 7 (1) (2024)
Marina H Yakou, Sonia Ghilas, Kelly Tran, Yang Liao, Shoukat Afshar-Sterle, Anita Kumari, Kevin Schmid, Christine Dijkstra, Chantelle Inguanti, Simone Ostrouska, Jordan Wilcox, Maxine Smith, Pavitha Parathan, Amr Allam, Hai-Hui Xue, Gabrielle T Belz, John M Mariadason, Andreas Behren, Grant R Drummond, Roland Ruscher, David S Williams, Bhupinder Pal, Wei Shi, Matthias Ernst, Dinesh Raghu, Lisa A Mielke
TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma. Science immunology 8 (88) (2023)
Pathum Thilakasiri, Ryan N O'Keefe, Sarah Q To, David Chisanga, Moritz F Eissmann, Annalisa LE Carli, Belinda Duscio, David Baloyan, Rhynelle S Dmello, David Williams, John M Mariadason, Ashleigh R Poh, Bhupinder Pal, Benjamin T Kile, Joseph H A Vissers, Kieran F Harvey, Michael Buchert, Wei Shi, Matthias Ernst, Ashwini L Chand
Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3. Life science alliance 7 (2) (2023)
Antonin Serrano, Tom S Weber, Jean Berthelet, Farrah El-Saafin, Sreeja Gadipally, Emmanuelle Charafe-Jauffret, Christophe Ginestier, John M Mariadason, Samantha R Oakes, Kara Britt, Shalin H Naik, Delphine Merino
Experimental and spontaneous metastasis assays can result in divergence in clonal architecture. Communications biology 6 (1) (2023)
Ian Y Luk, Laura J Jenkins, Kael L Schoffer, Irvin Ng, Janson W T Tse, Dmitri Mouradov, Stanislaw Kaczmarczyk, Rebecca Nightingale, Allan D Burrows, Robin L Anderson, Diego Arango, Higinio Dopeso, Larry Croft, Mark F Richardson, Oliver M Sieber, Yang Liao, Jennifer K Mooi, Natalia Vukelic, Camilla M Reehorst, Shoukat Afshar-Sterle, Vicki L J Whitehall, Lochlan J Fennell, Helen E Abud, Niall C Tebbutt, Wayne A Phillips, David S Williams, Wei Shi, Lisa A Mielke, Matthias Ernst, Amardeep S Dhillon, Nicholas James Clemons, John M Mariadason
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression. Cell death and differentiation 29 (11) (2022)
Fiona Chionh, Val Gebski, Sheren J Al-Obaidi, Jennifer K Mooi, Maressa A Bruhn, Chee K Lee, Anderly C Chüeh, David S Williams, Andrew J Weickhardt, Kate Wilson, Andrew M Scott, John Simes, Jennifer E Hardingham, Timothy J Price, John M Mariadason, Niall C Tebbutt
VEGF-A, VEGFR1 and VEGFR2 single nucleotide polymorphisms and outcomes from the AGITG MAX trial of capecitabine, bevacizumab and mitomycin C in metastatic colorectal cancer. Scientific reports 12 (1) (2022)
Laura J Jenkins, Ian Y Luk, Walter Douglas Fairlie, Erinna F Lee, Michelle Palmieri, Kael L Schoffer, Tao Tan, Irvin Ng, Natalia Vukelic, Sharon Tran, Janson Wt Tse, Rebecca Nightingale, Zakia Alam, Fiona Chionh, George Iatropoulos, Matthias Ernst, Shoukat Afshar-Sterle, Jayesh Desai, Peter Gibbs, Oliver M Sieber, Amardeep S Dhillon, Niall C Tebbutt, John M Mariadason
Genotype-tailored ERK/MAPK pathway and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death. Molecular cancer therapeutics (2022)
Anderly C Chüeh, Gahana Advani, Momeneh Foroutan, Jai Smith, Nadia Ng, Harshal Nandurkar, Daisy S Lio, Hong-Jian Zhu, Yuh-Ping Chong, Heather Verkade, Donald J Fujita, Jeffrey Bjorge, Faiza Basheer, Jet Phey Lim, Ian Luk, Amardeep Dhillon, Anuratha Sakthianandeswaren, Dmitri Mouradov, Oliver Sieber, Frédéric Hollande, John M Mariadason, Heung-Chin Cheng
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation. Oncogene 40 (17) (2021)
Camilla M Reehorst, Rebecca Nightingale, Ian Y Luk, Laura Jenkins, Frank Koentgen, David S Williams, Charbel Darido, Fiona Tan, Holly Anderton, Michael Chopin, Kael Schoffer, Moritz F Eissmann, Michael Buchert, Dmitri Mouradov, Oliver M Sieber, Matthias Ernst, Amardeep S Dhillon, John M Mariadason
EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis. Development (Cambridge, England) 148 (12) (2021)
Surein Arulananda, Megan O'Brien, Marco Evangelista, Laura J Jenkins, Ashleigh R Poh, Marzena Walkiewicz, Trishe Leong, John M Mariadason, Jonathan Cebon, Srividya B Balachander, Justin R Cidado, Erinna F Lee, Thomas John, Walter Douglas Fairlie
A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma. Cell death discovery 7 (1) (2021)
Sarah Bazzocco, Higinio Dopeso, Águeda Martinez Barriocanal, Estefanía Anguita, Rocío Nieto, Jing Li, Elia García-Vidal, Valentina Maggio, Paulo Rodrigues, Priscila Guimarães de Marcondes, Simó Schwartz, Lauri A Aaltonen, Álex Sánchez-Pla, John M Mariadason, Diego Arango
Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis. Clinical epigenetics 13 (1) (2021)
Surein Arulananda, Megan O'Brien, Marco Evangelista, Tiffany J Harris, Nikita S Steinohrt, Laura J Jenkins, Marzena Walkiewicz, Robert J J O'Donoghue, Ashleigh R Poh, Bibhusal Thapa, David S Williams, Trishe Leong, John M Mariadason, Xia Li, Jonathan Cebon, Erinna F Lee, Thomas John, Walter Douglas Fairlie
BCL-XL is an actionable target for treatment of malignant pleural mesothelioma. Cell death discovery 6 (1) (2020)
Mercedes Dávalos-Salas, Magdalene K Montgomery, Camilla M Reehorst, Rebecca Nightingale, Irvin Ng, Holly Anderton, Sheren Al-Obaidi, Analia Lesmana, Cameron M Scott, Paul Ioannidis, Hina Kalra, Shivakumar Keerthikumar, Lars Tögel, Angela Rigopoulos, Sylvia J Gong, David S Williams, Prusoth Yoganantharaja, Kim S Bell-Anderson, Suresh Mathivanan, Yann Gibert, Scott Hiebert, Andrew M Scott, Matthew J Watt, John M Mariadason
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. Nature communications 10 (1) (2019)
Ian Y Luk, Camilla M Reehorst, John M Mariadason
ELF3, ELF5, EHF and SPDEF Transcription Factors in Tissue Homeostasis and Cancer. Molecules (Basel, Switzerland) 23 (9) (2018)
Anand Kumar Meka, Laura J Jenkins, Mercedes Dávalos-Salas, Naisarg Pujara, Kuan Yau Wong, Tushar Kumeria, John M Mariadason, Amirali Popat
Enhanced Solubility, Permeability and Anticancer Activity of Vorinostat Using Tailored Mesoporous Silica Nanoparticles. Pharmaceutics 10 (4) (2018)