John P Richard

Scopus Author ID Scopus Author ID Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

Biochemistry

Journal of the American Chemical Society

Accounts of chemical research

University at Buffalo

Ohio State University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University at Buffalo Aug 01 1993

United States

SUNY Distinguished Professor :: Chemistry

University of Kentucky Sep 01 1985 - Jul 31 1993

United States

Professor :: Chemistry

Education History

Ohio State University Oct 01 1974 - Aug 01 1979

United States

PHD :: Biochemistry

Ohio State University Oct 01 1970 - Jun 01 1974

United States

BSC :: Chemistry

Publications

Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry 63 (8) (2024)
Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry 63 (8) (2024)
Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry (2024)
Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry 63 (8) (2024)
Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry 63 (8) (2024)
Judith R Cristobal, Rania Hegazy, John P Richard
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction. Biochemistry 63 (8) (2024)
John P Richard
The Role of the Substrate Phosphodianion in Catalysis by Orotidine 5'-Monophosphate Decarboxylase. Biochemistry 62 (5) (2023)
Rania Hegazy, John P Richard
Triosephosphate Isomerase: The Crippling Effect of the P168A/I172A Substitution at the Heart of an Enzyme Active Site. Biochemistry (2023)
Rania Hegazy, Gabriele Cordara, Rik K Wierenga, John P Richard
The Role of Asn11 in Catalysis by Triosephosphate Isomerase. Biochemistry (2023)
John P Richard
The Role of the Substrate Phosphodianion in Catalysis by Orotidine 5'-Monophosphate Decarboxylase. Biochemistry (2023)
Judith R Cristobal, Richard W Nagorski, John P Richard
Utilization of Cofactor Binding Energy for Enzyme Catalysis: Formate Dehydrogenase-Catalyzed Reactions of the Whole NAD Cofactor and Cofactor Pieces. Biochemistry (2023)
John P Richard
The Role of the Substrate Phosphodianion in Catalysis by Orotidine 5'-Monophosphate Decarboxylase. Biochemistry 62 (5) (2023)
Judith R Cristobal, John P Richard
Glycerol-3-Phosphate Dehydrogenase: The K120 and K204 Side Chains Define an Oxyanion Hole at the Enzyme Active Site. Biochemistry 61 (10) (2022)
John P Richard
Enabling Role of Ligand-Driven Conformational Changes in Enzyme Evolution. Biochemistry 61 (15) (2022)
Patrick L Fernandez, John P Richard
Adenylate Kinase-Catalyzed Reactions of AMP in Pieces: Specificity for Catalysis at the Nucleoside Activator and Dianion Catalytic Sites. Biochemistry 61 (23) (2022)
John P Richard, Judith R Cristobal, Tina L Amyes
Linear Free Energy Relationships for Enzymatic Reactions: Fresh Insight from a Venerable Probe. Accounts of chemical research 54 (10) (2021)
Patrick L Fernandez, John P Richard
Adenylate Kinase-Catalyzed Reaction of AMP in Pieces: Enzyme Activation for Phosphoryl Transfer to Phosphite Dianion. Biochemistry 60 (35) (2021)
Patrick L Fernandez, Richard W Nagorski, Judith R Cristobal, Tina L Amyes, John P Richard
Phosphodianion Activation of Enzymes for Catalysis of Central Metabolic Reactions. Journal of the American Chemical Society 143 (7) (2021)
Judith R Cristobal, Tiago A S Brandão, Archie C Reyes, John P Richard
Protein-Ribofuranosyl Interactions Activate Orotidine 5'-Monophosphate Decarboxylase for Catalysis. Biochemistry 60 (45) (2021)
Shaoyuan Zhou, Bach T Nguyen, John P Richard, Ronald Kluger, Jiali Gao
Correction to "Origin of Free Energy Barriers of Decarboxylation and the Reverse Process of CO2 Capture in Dimethylformamide and in Water". Journal of the American Chemical Society 143 (15) (2021)
Tiago A S Brandão, John P Richard
Orotidine 5'-Monophosphate Decarboxylase: The Operation of Active Site Chains Within and Across Protein Subunits. Biochemistry 59 (21) (2020)
Rui He, Judith R Cristobal, Naiji Jabin Gong, John P Richard
Hydride Transfer Catalyzed by Glycerol Phosphate Dehydrogenase: Recruitment of an Acidic Amino Acid Side Chain to Rescue a Damaged Enzyme. Biochemistry 59 (51) (2020)
Judith R Cristobal, Archie C Reyes, John P Richard
The Organization of Active Site Side Chains of Glycerol-3-phosphate Dehydrogenase Promotes Efficient Enzyme Catalysis and Rescue of Variant Enzymes. Biochemistry 59 (16) (2020)
Shaoyuan Zhou, Bach T Nguyen, John P Richard, Ronald Kluger, Jiali Gao
Origin of Free Energy Barriers of Decarboxylation and the Reverse Process of CO2 Capture in Dimethylformamide and in Water. Journal of the American Chemical Society 143 (1) (2020)
Yashraj S Kulkarni, Tina L Amyes, John P Richard, Shina Caroline Lynn Kamerlin
Uncovering the Role of Key Active-Site Side Chains in Catalysis: An Extended Brønsted Relationship for Substrate Deprotonation Catalyzed by Wild-Type and Variants of Triosephosphate Isomerase. Journal of the American Chemical Society 141 (40) (2019)
John P Richard
Protein Flexibility and Stiffness Enable Efficient Enzymatic Catalysis. Journal of the American Chemical Society 141 (8) (2019)
Lisa S Mydy, Judith R Cristobal, Roberto D Katigbak, Paul Bauer, Archie C Reyes, Shina Caroline Lynn Kamerlin, John P Richard, Andrew M Gulick
Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies. Biochemistry 58 (8) (2019)
Bogdana Goryanova, Tina L Amyes, John P Richard
Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization. Journal of the American Chemical Society 141 (34) (2019)
Xiang Zhai, Christopher J Reinhardt, M Merced Malabanan, Tina L Amyes, John P Richard
Enzyme Architecture: Amino Acid Side-Chains That Function To Optimize the Basicity of the Active Site Glutamate of Triosephosphate Isomerase. Journal of the American Chemical Society 140 (26) (2018)
Yashraj S Kulkarni, Qinghua Liao, Fabian Byléhn, Tina L Amyes, John P Richard, Shina Caroline Lynn Kamerlin
Role of Ligand-Driven Conformational Changes in Enzyme Catalysis: Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase. Journal of the American Chemical Society 140 (11) (2018)
Archie C Reyes, Tina L Amyes, John P Richard
Primary Deuterium Kinetic Isotope Effects: A Probe for the Origin of the Rate Acceleration for Hydride Transfer Catalyzed by Glycerol-3-Phosphate Dehydrogenase. Biochemistry 57 (29) (2018)
Rui He, Archie C Reyes, Tina L Amyes, John P Richard
Enzyme Architecture: The Role of a Flexible Loop in Activation of Glycerol-3-phosphate Dehydrogenase for Catalysis of Hydride Transfer. Biochemistry 57 (23) (2018)
John P Richard, Tina L Amyes, Archie C Reyes
Orotidine 5'-Monophosphate Decarboxylase: Probing the Limits of the Possible for Enzyme Catalysis. Accounts of chemical research 51 (4) (2018)
Archie C Reyes, David C Plache, Astrid P Koudelka, Tina L Amyes, John A Gerlt, John P Richard
Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5'-Monophosphate Decarboxylase for Catalysis. Journal of the American Chemical Society 140 (50) (2018)
Archie C Reyes, Tina L Amyes, John P Richard
Enzyme Architecture: Erection of Active Orotidine 5'-Monophosphate Decarboxylase by Substrate-Induced Conformational Changes. Journal of the American Chemical Society 139 (45) (2017)
Yashraj S Kulkarni, Qinghua Liao, Dušan Petrović, Dennis M Krüger, Birgit Strodel, Tina L Amyes, John P Richard, Shina Caroline Lynn Kamerlin
Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase. Journal of the American Chemical Society 139 (30) (2017)

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Publication Activity (10 Years)

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John P Richard