Jonathan Bones

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

Analytical chemistry

International journal of molecular sciences

Journal of proteome research

Biotechnology and bioengineering

University College Dublin

Dublin City University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University College Dublin Sep 01 2016

Ireland

Associate Professor :: Chemical and Bioprocess Engineering

National Institute for Bioprocessing Research and Training

Ireland

Principal Investigator :: Characterisation and Comparability Laboratory

Northeastern University

United States

John Hatsopoulos Research Fellow :: Barnett Institute of Chemical and Biological Analysis

National Institute for Bioprocessing Research and Training

Ireland

Postdoctoral Researcher :: GlycoScience Laboratory

Dublin City University

Ireland

Postdoctoral Researcher :: Centre for Bioanalytical Science

Education History

Dublin City University

Ireland

PHD :: School of Chemical Sciences

Dublin City University

Ireland

BSC :: School of Chemical Sciences

Publications

Peter T Beernink, Cristina Di Carluccio, Roberta Marchetti, Linda Cerofolini, Sara Carillo, Alessandro Cangiano, Nathan Cowieson, Jonathan Bones, Antonio Molinaro, Luigi Paduano, Marco Fragai, Benjamin P Beernink, Sunita Gulati, Jutamas Shaughnessy, Peter A Rice, Sanjay Ram, Alba Silipo
Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody. JACS Au 4 (7) (2024)
Peter T Beernink, Cristina Di Carluccio, Roberta Marchetti, Linda Cerofolini, Sara Carillo, Alessandro Cangiano, Nathan Cowieson, Jonathan Bones, Antonio Molinaro, Luigi Paduano, Marco Fragai, Benjamin P Beernink, Sunita Gulati, Jutamas Shaughnessy, Peter A Rice, Sanjay Ram, Alba Silipo
Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody. JACS Au 4 (7) (2024)
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency. International journal of molecular sciences 25 (5) (2024)
Ciaran Buckley, Ciara MacHale, Jonathan Bones
Quantitative Analysis of Poloxamer 188 in Biotherapeutic Process Streams Using Liquid Chromatography-Triple-Quadrupole Mass Spectrometry. ACS omega 9 (13) (2024)
Ciaran Buckley, Ciara MacHale, Jonathan Bones
Quantitative Analysis of Poloxamer 188 in Biotherapeutic Process Streams Using Liquid Chromatography-Triple-Quadrupole Mass Spectrometry. ACS omega 9 (13) (2024)
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency. International journal of molecular sciences 25 (5) (2024)
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency. International journal of molecular sciences 25 (5) (2024)
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency. International journal of molecular sciences 25 (5) (2024)
Zachary D Dunn, Patrick Bohman, Alexis Quinteros, Brian Sauerborn, Felix Milman, Misaal Patel, Roli Kargupta, Suyang Wu, Martin Hornshaw, Rodell Barrientos, Jonathan Bones, Venkata S Tayi, Nicholas Abaroa, Bhumit A Patel, Emmanuel Appiah-Amponsah, Erik L Regalado
Automated Online-Sampling Multidimensional Liquid Chromatography with Feedback-Control Capability as a Framework for Real-Time Monitoring of mAb Critical Quality Attributes in Multiple Bioreactors. Analytical chemistry (2023)
Josh Smith, Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Steven G Milian, Richard O Snyder, Jonathan Bones
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins. Journal of proteome research (2023)
Josh Smith, Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Steven G Milian, Richard O Snyder, Jonathan Bones
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins. Journal of proteome research (2023)
Lisa Strasser, Florian Füssl, Tomos E Morgan, Sara Carillo, Jonathan Bones
Exploring Charge-Detection Mass Spectrometry on Chromatographic Time Scales. Analytical chemistry (2023)
Josh Smith, Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Steven G Milian, Richard O Snyder, Jonathan Bones
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins. Journal of proteome research (2023)
Felipe Guapo, Florian Füssl, Lisa Strasser, Jonathan Bones
Mass spectrometry friendly pH-gradient anion exchange chromatography for the separation of full and empty adeno-associated virus (AAV) capsids. Analytical methods : advancing methods and applications (2023)
Silvia Millán-Martín, Craig Jakes, Sara Carillo, Richard Rogers, Da Ren, Jonathan Bones
Comprehensive multi-attribute method workflow for biotherapeutic characterization and current good manufacturing practices testing. Nature protocols (2022)
Tomos E Morgan, Craig Jakes, Hendrik-Jan Brouwer, Silvia Millán-Martín, Jean-Pierre Chervet, Ken Cook, Sara Carillo, Jonathan Bones
Inline electrochemical reduction of NISTmAb for middle-up subunit liquid chromatography-mass spectrometry analysis. The Analyst 146 (21) (2021)
Lisa Strasser, Tomos E Morgan, Felipe Guapo, Florian Füssl, Daniel Forsey, Ian Anderson, Jonathan Bones
A Native Mass Spectrometry-Based Assay for Rapid Assessment of the Empty:Full Capsid Ratio in Adeno-Associated Virus Gene Therapy Products. Analytical chemistry 93 (38) (2021)
Ioanna Tzani, Nicholas Herrmann, Sara Carillo, Cathy A Spargo, Ryan Hagan, Niall Barron, Jonathan Bones, W Shannon Dillmore, Colin Clarke
Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics. Biotechnology and bioengineering 118 (5) (2021)
Craig Jakes, Silvia Millán-Martín, Sara Carillo, Kai Scheffler, Izabela Zaborowska, Jonathan Bones
Tracking the Behavior of Monoclonal Antibody Product Quality Attributes Using a Multi-Attribute Method Workflow. Journal of the American Society for Mass Spectrometry 32 (8) (2021)
Lisa Strasser, Stefano Boi, Felipe Guapo, Nicholas Donohue, Niall Barron, Alana Rainbow-Fletcher, Jonathan Bones
Proteomic Landscape of Adeno-Associated Virus (AAV)-Producing HEK293 Cells. International journal of molecular sciences 22 (21) (2021)
Patrick Floris, Noemí Dorival-García, Graham Lewis, Graham Josland, Daniel Merriman, Jonathan Bones
Real-time characterization of mammalian cell culture bioprocesses by magnetic sector MS. Analytical methods : advancing methods and applications 12 (46) (2021)
Craig Jakes, Florian Füssl, Izabela Zaborowska, Jonathan Bones
Rapid Analysis of Biotherapeutics Using Protein A Chromatography Coupled to Orbitrap Mass Spectrometry. Analytical chemistry 93 (40) (2021)
Florian Füssl, Anne Trappe, Sara Carillo, Craig Jakes, Jonathan Bones
Comparative Elucidation of Cetuximab Heterogeneity on the Intact Protein Level by Cation Exchange Chromatography and Capillary Electrophoresis Coupled to Mass Spectrometry. Analytical chemistry 92 (7) (2020)
Jesús Hermosilla, Raquel Pérez-Robles, Antonio Salmerón-García, Salvador Casares, Jose Cabeza, Jonathan Bones, Natalia Navas
Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation. Scientific reports 10 (1) (2020)
Ioanna Tzani, Craig Monger, Krishna Motheramgari, Clair Gallagher, Ryan Hagan, Paul S Kelly, Alan Costello, Justine Meiller, Patrick Floris, Lin Zhang, Martin Clynes, Jonathan Bones, Niall Barron, Colin Clarke
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells. Biotechnology and bioengineering 117 (8) (2020)
Roland Imle, Bei-Tzu Wang, Nicolas Stützenberger, Jana Birkenhagen, Amol Tandon, Matthias Carl, Nastassja Himmelreich, Christian Thiel, Hermann-Josef Gröne, Gernot Poschet, Mirko Völkers, Karsten Gülow, Anne Schröder, Sara Carillo, Jonathan Bones, Jonathan Bones, Marcin Mikołaj Kamiński, Stefan Kölker, Sven Wolfgang Sauer
ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing. Scientific reports 9 (1) (2019)
Florian Füssl, Angela Criscuolo, Ken Cook, Kai Scheffler, Jonathan Bones
Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography-High-Resolution Mass Spectrometry under Native Conditions. Journal of proteome research 18 (10) (2019)
Csaba Váradi, Károly Nehéz, Olivér Hornyák, Béla Viskolcz, Jonathan Bones
Serum N-Glycosylation in Parkinson's Disease: A Novel Approach for Potential Alterations. Molecules (Basel, Switzerland) 24 (12) (2019)
Simone Albrecht, Christian Kaisermayer, Clair Gallagher, Amy Farrell, Anna Lindeberg, Jonathan Bones
Proteomics in biomanufacturing control: Protein dynamics of CHO-K1 cells and conditioned media during apoptosis and necrosis. Biotechnology and bioengineering 115 (6) (2018)
Patrick Floris, Sean Curtin, Christian Kaisermayer, Anna Lindeberg, Jonathan Bones
Development of a versatile high-temperature short-time (HTST) pasteurization device for small-scale processing of cell culture medium formulations. Applied microbiology and biotechnology 102 (13) (2018)
Florian Füssl, Ken Cook, Kai Scheffler, Amy Farrell, Jonathan Bones, Jonathan Bones
Charge Variant Analysis of Monoclonal Antibodies Using Direct Coupled pH Gradient Cation Exchange Chromatography to High-Resolution Native Mass Spectrometry. Analytical chemistry 90 (7) (2018)
Josh Smith, Jonathan Bones, Csaba Váradi, Jonathan Bones
Quantitative glycomics using liquid phase separations coupled to mass spectrometry. The Analyst 142 (5) (2018)
Florian Füssl, Anne Trappe, Ken Cook, Kai Scheffler, Oliver Fitzgerald, Jonathan Bones
Comprehensive characterisation of the heterogeneity of adalimumab via charge variant analysis hyphenated on-line to native high resolution Orbitrap mass spectrometry. mAbs 11 (1) (2018)
Noemí Dorival-García, Sara Carillo, Christine Ta, Dominic Roberts, Kate Comstock, Simon Lofthouse, Elena Ciceri, Kyle D'Silva, Gerald Kierans, Christian Kaisermayer, Anna Lindeberg, Jonathan Bones
Large-Scale Assessment of Extractables and Leachables in Single-Use Bags for Biomanufacturing. Analytical chemistry 90 (15) (2018)
Patrick Floris, Nicola McGillicuddy, Simone Albrecht, Brian Morrissey, Christian Kaisermayer, Anna Lindeberg, Jonathan Bones
Untargeted LC-MS/MS Profiling of Cell Culture Media Formulations for Evaluation of High Temperature Short Time Treatment Effects. Analytical chemistry 89 (18) (2017)
Nicola McGillicuddy, Patrick Floris, Simone Albrecht, Jonathan Bones
Examining the sources of variability in cell culture media used for biopharmaceutical production. Biotechnology letters 40 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jonathan Bones