Jonathan Karn (J Karn)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Topics

Men Who Have Sex With Men

Antiretroviral Therapy

Regulatory T Cells

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Fredrick Kizito, Kien Nguyen, Uri Mbonye, Meenakshi Shukla, Benjamin Luttge, Mary Ann Checkley, Anna Agaponova, Konstantin Leskov, Jonathan Karn
Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Fredrick Kizito, Kien Nguyen, Uri Mbonye, Meenakshi Shukla, Benjamin Luttge, Mary Ann Checkley, Anna Agaponova, Konstantin Leskov, Jonathan Karn
Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Fredrick Kizito, Kien Nguyen, Uri Mbonye, Meenakshi Shukla, Benjamin Luttge, Mary Ann Checkley, Anna Agaponova, Konstantin Leskov, Jonathan Karn
Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Ethan Honeycutt, Fredrick Kizito, Jonathan Karn, Thomas Sweet
Direct Analysis of HIV mRNA m 6 A Methylation by Nanopore Sequencing. Methods in molecular biology (Clifton, N.J.) 2807 (2024)
Harpreet Kaur, Paige Minchella, David Alvarez-Carbonell, Neeraja Purandare, Nagampalli Vijaykrishna, Daniel Blankenberg, Todd Hulgan, Mariana Gerschenson, Jonathan Karn, Siddhesh Aras, Asha R Kallianpur
Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells. International journal of molecular sciences 24 (15) (2023)
Debjit Khan, Fulvia Terenzi, Guan Qun Liu, Prabar K Ghosh, Fengchun Ye, Kien Nguyen, Arnab China, Iyappan Ramachandiran, Shruti Chakraborty, Jennifer Stefan, Krishnendu Khan, Kommireddy Vasu, Franklin Dong, Belinda Willard, Jonathan Karn, Michaela U Gack, Paul L Fox
A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon. Nature communications 14 (1) (2023)
Iart Luca Shytaj, Francesco Andrea Procopio, Mohammad Tarek, Irene Carlon-Andres, Hsin-Yao Tang, Aaron R Goldman, MohamedHusen Munshi, Virender Kumar Pal, Mattia Forcato, Sheetal Sreeram, Konstantin Leskov, Fengchun Ye, Bojana Lucic, Nicolly Cruz, Lishomwa C Ndhlovu, Silvio Bicciato, Sergi Padilla-Parra, Ricardo Sobhie Diaz, Amit Singh, Marina Lusic, Jonathan Karn, David Alvarez-Carbonell, Andrea Savarino
Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress. EMBO molecular medicine 13 (8) (2021)
Uri Mbonye, Konstantin Leskov, Meenakshi Shukla, Saba Valadkhan, Jonathan Karn
Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways. PLoS pathogens 17 (9) (2021)
N Bhaskaran, E Schneider, F Faddoul, A Paes da Silva, R Asaad, A Talla, N Greenspan, Alan D Levine, D McDonald, Jonathan Karn, M M Lederman, P Pandiyan
Oral immune dysfunction is associated with the expansion of FOXP3+PD-1+Amphiregulin+ T cells during HIV infection. Nature communications 12 (1) (2021)
Kien Nguyen, Curtis N Dobrowolski, Meenakshi Shukla, Won-Kyung Cho, Benjamin Luttge, Jonathan Karn
Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation. PLoS pathogens 17 (10) (2021)
David Alvarez-Carbonell, Fengchun Ye, Nirmala Ramanath, Yoelvis Garcia-Mesa, Pamela E Knapp, Kurt F Hauser, Jonathan Karn
Cross-talk between microglia and neurons regulates HIV latency. PLoS pathogens 15 (12) (2019)
Biswajit Das, Curtis Dobrowolski, Benjamin Luttge, Saba Valadkhan, Nicolas Chomont, Rowena Johnston, Peter Bacchetti, Rebecca Hoh, Monica Gandhi, Steven G Deeks, Eileen Scully, Jonathan Karn
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proceedings of the National Academy of Sciences of the United States of America 115 (33) (2018)
Lechuang Chen, Zhimin Feng, Hong Yue, Douglas Bazdar, Uri Mbonye, Chad Zender, Clifford V Harding, Leslie A Bruggeman, Jonathan Karn, Scott F Sieg, Bingcheng Wang, Ge Jin
Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA. Nature communications 9 (1) (2018)