Ju-Hyun Lee

Publication Activity (10 Years)

Years Active: 2022-2023
Publications (10 Years): 4

Top Topics

Lipopolysaccharide Induced

Cognitive Decline

Top Venues

Science advances

Nature neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Eunju Im, Ying Jiang, Philip H Stavrides, Sandipkumar Darji, Hediye Erdjument-Bromage, Thomas A Neubert, Jun Yong Choi, Jerzy Wegiel, Ju-Hyun Lee, Ralph A Nixon
Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr 682 -phosphorylated APP βCTF. Science advances 9 (30) (2023)
Ju-Hyun Lee, Ralph A Nixon
Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis. Autophagy 18 (11) (2022)
Pearl P Y Lie, Lang Yoo, Chris N Goulbourne, Martin J Berg, Philip Stavrides, Chunfeng Huo, Ju-Hyun Lee, Ralph A Nixon
Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function. Science advances 8 (17) (2022)
Ju-Hyun Lee, Dun-Sheng Yang, Chris N Goulbourne, Eunju Im, Philip Stavrides, Anna Pensalfini, Han Chan, Cedric Bouchet-Marquis, Cynthia Bleiwas, Martin J Berg, Chunfeng Huo, James Peddy, Monika Pawlik, Efrat Levy, Mala Rao, Mathias Staufenbiel, Ralph A Nixon
Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques. Nature neuroscience 25 (6) (2022)