Malcolm Irving

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 14

Top Topics

Binding Protein

Hypertrophic Cardiomyopathy

Skeletal Muscle

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

The Journal of general physiology

The Journal of physiology

Nature reviews. Cardiology

This page only lists publications with an associated author ORCID identifier.

Publications

Malcolm Irving
Functional control of myosin motors in the cardiac cycle. Nature reviews. Cardiology (2024)
Jessica Chandler, Conor Treacy, Simon Ameer-Beg, Elisabeth Ehler, Malcolm Irving, Thomas Kampourakis
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Marco Caremani, Luca Fusi, Massimo Reconditi, Gabriella Piazzesi, Theyencheri Narayanan, Malcolm Irving, Vincenzo Lombardi, Marco Linari, Elisabetta Brunello
Dependence of myosin filament structure on intracellular calcium concentration in skeletal muscle. The Journal of general physiology 155 (12) (2023)
Jessica Chandler, Conor Treacy, Simon Ameer-Beg, Elisabeth Ehler, Malcolm Irving, Thomas Kampourakis
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Elisabetta Brunello, Lorenzo Marcucci, Malcolm Irving, Luca Fusi
Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism. Proceedings of the National Academy of Sciences of the United States of America 120 (22) (2023)
Jessica Chandler, Conor Treacy, Simon Ameer-Beg, Elisabeth Ehler, Malcolm Irving, Thomas Kampourakis
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Jessica Chandler, Conor Treacy, Simon Ameer-Beg, Elisabeth Ehler, Malcolm Irving, Thomas Kampourakis
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Cameron Hill, Elisabetta Brunello, Luca Fusi, Jesús Garcia Ovejero, Malcolm Irving
Activation of the myosin motors in fast-twitch muscle of the mouse is controlled by mechano-sensing in the myosin filaments. The Journal of physiology 600 (17) (2022)
Jesús Garcia Ovejero, Luca Fusi, So-Jin Park-Holohan, Andrea Ghisleni, Theyencheri Narayanan, Malcolm Irving, Elisabetta Brunello
Cooling intact and demembranated trabeculae from rat heart releases myosin motors from their inhibited conformation. The Journal of general physiology 154 (3) (2022)
Cameron Hill, Elisabetta Brunello, Luca Fusi, Jesús Garcia Ovejero, Malcolm Irving
Myosin-based regulation of twitch and tetanic contractions in mammalian skeletal muscle. eLife 10 (2021)
Massimo Reconditi, Elisabetta Brunello, Luca Fusi, Marco Linari, Vincenzo Lombardi, Malcolm Irving, Gabriella Piazzesi
Myosin motors that cannot bind actin leave their folded OFF state on activation of skeletal muscle. The Journal of general physiology 153 (11) (2021)
So-Jin Park-Holohan, Elisabetta Brunello, Thomas Kampourakis, Martin Rees, Malcolm Irving, Luca Fusi
Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing. Proceedings of the National Academy of Sciences of the United States of America 118 (16) (2021)
Elisabetta Brunello, Luca Fusi, Andrea Ghisleni, So-Jin Park-Holohan, Jesus G Ovejero, Theyencheri Narayanan, Malcolm Irving
Myosin filament-based regulation of the dynamics of contraction in heart muscle. Proceedings of the National Academy of Sciences of the United States of America 117 (14) (2020)
Thomas Kampourakis, Xuemeng Zhang, Yin-Biao Sun, Malcolm Irving
Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament. The Journal of physiology 596 (1) (2017)