Michael Downes

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 28

Top Topics

Histone Deacetylase

Epithelial Mesenchymal Transition

Inflammatory Response

Signaling Pathway

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Jason S Seidman, Ty D Troutman, Joshua D Stender, Havilah Taylor, Weiwei Fan, Verena M Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M Evans, James T Kadonaga, Michael G Rosenfeld, Christopher K Glass
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Suk-Hyun Hong, Glenda Castro, Dan Wang, Russell Nofsinger, Maureen Kane, Alexandra Folias, Annette R Atkins, Ruth T Yu, Joseph L Napoli, Paolo Sassone-Corsi, Dirk G de Rooij, Christopher Liddle, Michael Downes, Ronald M Evans
Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Min Young Kim, Hyun Young Shin, Sung Chun Cho, Sohae Yang, Aseer Intisar, Hyeong Jung Woo, Youn-Suk Choi, Chang-Lim You, Jong-Sun Kang, Yun-Il Lee, Sang Chul Park, Kyungmoo Yea, Tae Gyu Oh, Michael Downes, Ronald M Evans, Minseok S Kim
Silver electroceutical technology to treat sarcopenia. Proceedings of the National Academy of Sciences of the United States of America 120 (33) (2023)
Gaoyang Liang, Tae Gyu Oh, Nasun Hah, Hervé Tiriac, Yu Shi, Morgan L Truitt, Corina E Antal, Annette R Atkins, Yuwenbin Li, Cory Fraser, Serina Ng, Antonio F M Pinto, Dylan C Nelson, Gabriela Estepa, Senada Bashi, Ester Banayo, Yang Dai, Christopher Liddle, Ruth T Yu, Tony Hunter, Dannielle D Engle, Haiyong Han, Daniel D Von Hoff, Michael Downes, Ronald M Evans
Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression. bioRxiv : the preprint server for biology (2023)
Bo Kyung Yoon, Hyeonhui Kim, Tae Gyu Oh, Se Kyu Oh, Sugyeong Jo, Minki Kim, Kyu-Hye Chun, Nahee Hwang, Suji Lee, Suyon Jin, Annette R Atkins, Ruth T Yu, Michael Downes, Jae-Woo Kim, Hyunkyung Kim, Ronald M Evans, Jae-Ho Cheong, SungSoon Fang
PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress. Proceedings of the National Academy of Sciences of the United States of America 120 (21) (2023)
Bo Kyung Yoon, Hyeonhui Kim, Tae Gyu Oh, Se Kyu Oh, Sugyeong Jo, Minki Kim, Kyu-Hye Chun, Nahee Hwang, Suji Lee, Suyon Jin, Annette R Atkins, Ruth T Yu, Michael Downes, Jae-Woo Kim, Hyunkyung Kim, Ronald M Evans, Jae-Ho Cheong, SungSoon Fang
PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress. Proceedings of the National Academy of Sciences of the United States of America 120 (21) (2023)
Bo Kyung Yoon, Hyeonhui Kim, Tae Gyu Oh, Se Kyu Oh, Sugyeong Jo, Minki Kim, Kyu-Hye Chun, Nahee Hwang, Suji Lee, Suyon Jin, Annette R Atkins, Ruth T Yu, Michael Downes, Jae-Woo Kim, Hyunkyung Kim, Ronald M Evans, Jae-Ho Cheong, SungSoon Fang
PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress. Proceedings of the National Academy of Sciences of the United States of America 120 (21) (2023)
Nasiha S Ahmed, Jovylyn Gatchalian, Josephine Ho, Mannix J Burns, Nasun Hah, Zong Wei, Michael Downes, Ronald M Evans, Diana C Hargreaves
BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4. Proceedings of the National Academy of Sciences of the United States of America 119 (1) (2022)
Ting Fu, Yuwenbin Li, Tae Gyu Oh, Fritz Cayabyab, Nanhai He, Qin Tang, Sally Coulter, Morgan Truitt, Paul Medina, Mingxiao He, Ruth T Yu, Annette R Atkins, Ye Zheng, Christopher Liddle, Michael Downes, Ronald M Evans
FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (51) (2022)
Ting Fu, Yuwenbin Li, Tae Gyu Oh, Fritz Cayabyab, Nanhai He, Qin Tang, Sally Coulter, Morgan Truitt, Paul Medina, Mingxiao He, Ruth T Yu, Annette R Atkins, Ye Zheng, Christopher Liddle, Michael Downes, Ronald M Evans
FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (51) (2022)
Vera J M Nies, Dicky Struik, Sihao Liu, Weilin Liu, Janine K Kruit, Michael Downes, Tim van Zutphen, Henkjan J Verkade, Ronald M Evans, Johan W Jonker
Autocrine FGF1 signaling promotes glucose uptake in adipocytes. Proceedings of the National Academy of Sciences of the United States of America 119 (40) (2022)
Ting Fu, Yuwenbin Li, Tae Gyu Oh, Fritz Cayabyab, Nanhai He, Qin Tang, Sally Coulter, Morgan Truitt, Paul Medina, Mingxiao He, Ruth T Yu, Annette R Atkins, Ye Zheng, Christopher Liddle, Michael Downes, Ronald M Evans
FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (51) (2022)
Ting Fu, Yuwenbin Li, Tae Gyu Oh, Fritz Cayabyab, Nanhai He, Qin Tang, Sally Coulter, Morgan Truitt, Paul Medina, Mingxiao He, Ruth T Yu, Annette R Atkins, Ye Zheng, Christopher Liddle, Michael Downes, Ronald M Evans
FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (51) (2022)
Ting Fu, Yuwenbin Li, Tae Gyu Oh, Fritz Cayabyab, Nanhai He, Qin Tang, Sally Coulter, Morgan Truitt, Paul Medina, Mingxiao He, Ruth T Yu, Annette R Atkins, Ye Zheng, Christopher Liddle, Michael Downes, Ronald M Evans
FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (51) (2022)
Liu Wang, Tae Gyu Oh, Jason Magida, Gabriela Estepa, S M Bukola Obayomi, Ling-Wa Chong, Jovylyn Gatchalian, Ruth T Yu, Annette R Atkins, Diana C Hargreaves, Michael Downes, Zong Wei, Ronald M Evans
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. Proceedings of the National Academy of Sciences of the United States of America 118 (35) (2021)