Moritz J Frech

ORCID

Publication Activity (10 Years)

Years Active: 2017-2022
Publications (10 Years): 10

Top Venues

International journal of molecular sciences

Cells

Orphanet journal of rare diseases

University Medicine Rostock

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Medicine Rostock

Germany

Group Leader Cellular Neurophysiology :: Translational Neurodegeneration Section „Albrecht-Kossel“

Publications

Maik Liedtke, Christin Völkner, Andreas Hermann, Moritz J Frech
Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann-Pick Disease Type C. Cells 11 (3) (2022)
Christin Völkner, Supansa Pantoom, Maik Liedtke, Jan Lukas, Andreas Hermann, Moritz J Frech
Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems. Cells 11 (3) (2022)
Christin Völkner, Maik Liedtke, Robert Untucht, Andreas Hermann, Moritz J Frech
Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease. International journal of molecular sciences 22 (22) (2021)
Maik Liedtke, Christin Völkner, Alexandra V Jürs, Franziska Peter, Michael Rabenstein, Andreas Hermann, Moritz J Frech
Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the NPC2 Mutations c.58G>T/c.140G>T. International journal of molecular sciences 22 (8) (2021)
Christin Völkner, Maik Liedtke, Andreas Hermann, Moritz J Frech
Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1. International journal of molecular sciences 22 (2) (2021)
Alexandra V Jürs, Christin Völkner, Maik Liedtke, Katharina Huth, Jan Lukas, Andreas Hermann, Moritz J Frech
Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells. International journal of molecular sciences 21 (20) (2020)
Anne Gläser, Franziska Hammerl, Markus H Gräler, Sina M Coldewey, Christin Völkner, Moritz J Frech, Fan Yang, Jiankai Luo, Eric Tönnies, Oliver von Bohlen Und Halbach, Nicola Brandt, Diana Heimes, Anna-Maria Neßlauer, Georg Christoph Korenke, Marta Owczarek-Lipska, John Neidhardt, Arndt Rolfs, Andreas Wree, Martin Witt, Anja Ursula Bräuer
Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism. International journal of molecular sciences 21 (12) (2020)
Michael Rabenstein, Nico Murr, Andreas Hermann, Arndt Rolfs, Moritz J Frech
Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient Mice. International journal of molecular sciences 20 (24) (2019)
Xiao Feng, Claudia Cozma, Supansa Pantoom, Christina Hund, Katharina Iwanov, Janine Petters, Christin Völkner, Claudia Bauer, Florian Vogel, Peter Bauer, Frank U Weiss, Markus M Lerch, Anne-Marie Knospe, Andreas Hermann, Moritz J Frech, Jiankai Luo, Arndt Rolfs, Jan Lukas
Determination of the Pathological Features of NPC1 Variants in a Cellular Complementation Test. International journal of molecular sciences 20 (20) (2019)
Franziska Peter, Sebastian Rost, Arndt Rolfs, Moritz J Frech
Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis. Orphanet journal of rare diseases 12 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Moritz J Frech