Myung-Shik Lee

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Metabolic Syndrome

Top Venues

Journal of diabetes investigation

Nature communications

Cell death discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Xaviera Riani Yasasilka, Myung-Shik Lee
Role of β-cell autophagy in β-cell physiology and the development of diabetes. Journal of diabetes investigation 15 (6) (2024)
Xaviera Riani Yasasilka, Myung-Shik Lee
Role of β-cell autophagy in β-cell physiology and the development of diabetes. Journal of diabetes investigation 15 (6) (2024)
Hyereen Kang, Seong Woo Choi, Joo Young Kim, Soo-Jin Oh, Sung Joon Kim, Myung-Shik Lee
ER-to-lysosome Ca 2+ refilling followed by K + efflux-coupled store-operated Ca 2+ entry in inflammasome activation and metabolic inflammation. eLife 12 (2024)
Hyereen Kang, Seong Woo Choi, Joo Young Kim, Soo-Jin Oh, Sung Joon Kim, Myung-Shik Lee
ER-to-lysosome Ca 2+ refilling followed by K + efflux-coupled store-operated Ca 2+ entry in inflammasome activation and metabolic inflammation. eLife 12 (2024)
Xaviera Riani Yasasilka, Myung-Shik Lee
Role of β-cell autophagy in β-cell physiology and the development of diabetes. Journal of diabetes investigation 15 (6) (2024)
Hyereen Kang, Seong Woo Choi, Joo Young Kim, Soo-Jin Oh, Sung Joon Kim, Myung-Shik Lee
ER-to-lysosome Ca 2+ refilling followed by K + efflux-coupled store-operated Ca 2+ entry in inflammasome activation and metabolic inflammation. eLife 12 (2024)
Xaviera Riani Yasasilka, Myung-Shik Lee
Role of β-cell autophagy in β-cell physiology and the development of diabetes. Journal of diabetes investigation 15 (6) (2024)
Xaviera Riani Yasasilka, Myung-Shik Lee
Role of β-cell autophagy in β-cell physiology and the development of diabetes. Journal of diabetes investigation (2024)
Soo-Jin Oh, Kihyoun Park, Seong Keun Sonn, Goo Taeg Oh, Myung-Shik Lee
Pancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca 2+ release. Experimental & molecular medicine (2023)
Soo-Jin Oh, Yeseong Hwang, Kyu Yeon Hur, Myung-Shik Lee
Lysosomal Ca 2+ as a mediator of palmitate-induced lipotoxicity. Cell death discovery 9 (1) (2023)
Soo-Jin Oh, Yeseong Hwang, Kyu Yeon Hur, Myung-Shik Lee
Lysosomal Ca 2+ as a mediator of palmitate-induced lipotoxicity. Cell death discovery 9 (1) (2023)
Soo-Jin Oh, Masataka Ikeda, Tomomi Ide, Kyu Yeon Hur, Myung-Shik Lee
Correction: Mitochondrial event as an ultimate step in ferroptosis. Cell death discovery 8 (1) (2022)
Kihyoun Park, Myung-Shik Lee
Essential role of lysosomal Ca2+-mediated TFEB activation in mitophagy and functional adaptation of pancreatic β-cells to metabolic stress. Autophagy 18 (12) (2022)
Soo-Jin Oh, Masataka Ikeda, Tomomi Ide, Kyu Yeon Hur, Myung-Shik Lee
Mitochondrial event as an ultimate step in ferroptosis. Cell death discovery 8 (1) (2022)
Kihyoun Park, Hyejin Lim, Jinyoung Kim, Yeseong Hwang, Yu Seol Lee, Soo Han Bae, Hyeongseok Kim, Hail Kim, Shin-Wook Kang, Joo Young Kim, Myung-Shik Lee
Lysosomal Ca 2+ -mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic β-cells to metabolic stress. Nature communications 13 (1) (2022)
Kihyoun Park, Seong Keun Sonn, Seungwoon Seo, Jinyoung Kim, Kyu Yeon Hur, Goo Taeg Oh, Myung-Shik Lee
Impaired TFEB activation and mitophagy as a cause of PPP3/calcineurin inhibitor-induced pancreatic β-cell dysfunction. Autophagy (2022)
Soo-Jin Oh, Myung-Shik Lee
Role of Autophagy in the Pathogenesis of Diabetes and Therapeutic Potential of Autophagy Modulators in the Treatment of Diabetes and Metabolic Syndrome. Journal of Korean medical science 37 (37) (2022)
Bonggi Lee, Hye Jin An, Dae Hyun Kim, Min-Kyeong Lee, Hyeon Hak Jeong, Ki Wung Chung, Younghoon Go, Arnold Y Seo, Il Yong Kim, Je-Kyung Seong, Byung Pal Yu, Jaewon Lee, Eunok Im, In-Kyu Lee, Myung-Shik Lee, Ken-Ichi Yamada, Hae Young Chung
SMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice. Experimental & molecular medicine 54 (11) (2022)
Jinyoung Kim, Seong Hun Kim, Hyereen Kang, Soyeon Lee, Shi-Young Park, Yoonil Cho, Yu-Mi Lim, Ji Woong Ahn, Young-Hwan Kim, Seungsoo Chung, Cheol Soo Choi, Yeon Jin Jang, Hye Soon Park, Yoonseok Heo, Kook Hwan Kim, Myung-Shik Lee
TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response. Nature metabolism 3 (3) (2021)
Jinyoung Kim, Kihyoun Park, Min Jung Kim, Hyejin Lim, Kook Hwan Kim, Sun-Woo Kim, Eun-Seo Lee, Hyongbum Henry Kim, Sung Joo Kim, Kyu Yeon Hur, Jae Hyeon Kim, Jin Hee Ahn, Kun-Ho Yoon, Ji-Won Kim, Myung-Shik Lee
An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer. Nature communications 12 (1) (2021)
Hyun-Kyoung Kim, Geum-Hwa Lee, Kashi Raj Bhattarai, Myung-Shik Lee, Sung Hoon Back, Hyung-Ryong Kim, Han-Jung Chae
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium. Autophagy 17 (3) (2020)
So Ra Kim, Sang Guk Lee, Soo Hyun Kim, Jin Hee Kim, Eunhye Choi, Wonhee Cho, John Hoon Rim, Inhwa Hwang, Chan Joo Lee, Minyoung Lee, Chang-Myung Oh, Justin Y Jeon, Heon Yung Gee, Jeong Ho Kim, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Myung-Shik Lee, Je-Wook Yu, Jin Won Cho, Jung-Sun Kim, Eun Young Lee
SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease. Nature communications 11 (1) (2020)
Cassandra N Spracklen, Momoko Horikoshi, Young Jin Kim, Kuang Lin, Fiona Bragg, Sanghoon Moon, Ken Suzuki, Claudia Ha-Ting Tam, Yasuharu Tabara, Soo-Heon Kwak, Fumihiko Takeuchi, Jirong Long, Victor J Y Lim, Jin Fang Chai, Chien-Hsiun Chen, Masahiro Nakatochi, Jie Yao, Hyeok Sun Choi, Apoorva K Iyengar, Hannah J Perrin, Sarah M Brotman, Martijn van de Bunt, Anna L Gloyn, Jennifer E Below, Michael Boehnke, Donald W Bowden, John C Chambers, Anubha Mahajan, Mark I McCarthy, Maggie C Y Ng, Lauren E Petty, Weihua Zhang, Andrew P Morris, Linda S Adair, Masato Akiyama, Zheng Bian, Juliana C N Chan, Li-Ching Chang, Miao-Li Chee, Yii-Der Ida Chen, Yuan-Tsong Chen, Zhengming Chen, Lee-Ming Chuang, Shufa Du, Penny Gordon-Larsen, Myron Gross, Xiuqing Guo, Yu Guo, Sohee Han, Annie-Green Howard, Wei Huang, Yi-Jen Hung, Mi Yeong Hwang, Chii-Min Hwu, Sahoko Ichihara, Masato Isono, Hye-Mi Jang, Guozhi Jiang, Jost Bruno Jonas, Yoichiro Kamatani, Tomohiro Katsuya, Takahisa Kawaguchi, Chiea Chuen Khor, Katsuhiko Kohara, Myung-Shik Lee, Nanette R Lee, Liming Li, Jian-Jun Liu, Andrea O Luk, Jun Lv, Yukinori Okada, Mark A Pereira, Sabanayagam Charumathi, Jinxiu Shi, Dong Mun Shin, Wing Yee So, Atsushi Takahashi, Christopher Wai Kei Lam, Fuu-Jen Tsai, Rob M van Dam, Yong-Bing Xiang, Ken Yamamoto, Toshimasa Yamauchi, Kyungheon Yoon, Canqing Yu, Woon-Puay Koh, Liang Zhang, Quan Long, Michiya Igase, Yoon Shin Cho, Jerome I Rotter, Ya-Xing Wang, Wayne H H Sheu, Mitsuhiro Yokota, Jer-Yuarn Wu, Ching-Yu Cheng, Tien-Yin Wong, Xiao-Ou Shu, Norihiro Kato, Kyong-Soo Park, E-Shyong Tai, Fumihiko Matsuda, Woon-Puay Koh, Ronald Ching-Wan Ma, Shiro Maeda, Iona Y Millwood, Juyoung Lee, Takashi Kadowaki, Robin G Walters, Bong-Jo Kim, Karen L Mohlke, Xueling S Sim
Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature 582 (7811) (2020)
Wan-Young Kim, Sun Ah Nam, Arum Choi, Yu-Mi Kim, Sang Hee Park, Hong Lim Kim, Hyang Kim, Ki-Hwan Han, Chul Woo Yang, Myung-Shik Lee, Yong Kyun Kim, Jin Kim
Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia. Scientific reports 9 (1) (2019)
Ji Young Kim, Jihee Kim, Yuri Ahn, Eun Jung Lee, Shinwon Hwang, Abdurrahman I Almurayshid, Keedon Park, Hwa-Jee Chung, Heung Jae Kim, Si-Hyung Lee, Myung-Shik Lee, Sang Ho Oh
Autophagy induction can regulate skin pigmentation by causing melanosome degradation in keratinocytes and melanocytes. Pigment cell & melanoma research 33 (3) (2019)
Hyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn, Myung-Shik Lee
A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes. Nature communications 9 (1) (2018)
Kook Hwan Kim, Seong Hun Kim, Dai Hoon Han, Young Suk Jo, Eun Young Lee, Myung-Shik Lee
Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. Scientific reports 8 (1) (2018)
Soo Hyun Kim, Gyuri Kim, Dai Hoon Han, Milim Lee, Irene Kim, Bohkyung Kim, Kook Hwan Kim, Young-Mi Song, Jeong Eun Yoo, Hye Jin Wang, Soo Han Bae, Eun Young Lee, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Myung-Shik Lee
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Autophagy 13 (10) (2017)
June-Chul Lee, Hae-Youn Lee, Tae Kang Kim, Min-Soo Kim, Young Mi Park, Jinyoung Kim, Kihyoun Park, Mi-Na Kweon, Seok-Hyung Kim, Jin-Woo Bae, Kyu Yeon Hur, Myung-Shik Lee
Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis. PloS one 12 (11) (2017)
Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi, Takafumi Suzuki, Tsunehiro Mizushima, Kenji Takagi, Yuki Hirose, Masayuki Nagahashi, Tetsuro Iso, Toshiaki Fukutomi, Maki Ohishi, Keiko Endo, Takefumi Uemura, Yasumasa Nishito, Shujiro Okuda, Miki Obata, Tsuguka Kouno, Riyo Imamura, Yukio Tada, Rika Obata, Daisuke Yasuda, Kyoko Takahashi, Tsutomu Fujimura, Jingbo Pi, Myung-Shik Lee, Takashi Ueno, Tomoyuki Ohe, Tadahiko Mashino, Toshifumi Wakai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Hozumi Motohashi, Satoshi Waguri, Tomoyoshi Soga, Masayuki Yamamoto, Keiji Tanaka, Masaaki Komatsu
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nature communications 7 (2016)