Patricia Melnyk

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Venues

International journal of molecular sciences

ChemMedChem

Cells

Expert opinion on therapeutic patents

Université de Lille II

Université Pierre et Marie Curie (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Université de Lille II Sep 01 2002

France

Professor :: Pharmacy Faculty

CEREP Feb 01 2000 - Sep 30 2001

France

Head of Department :: Combinatorial Chemistry

CEREP Oct 15 1996 - Jan 31 2000

France

Researcher :: Combinatorial Chemistry

Institut Pasteur de Lille Sep 01 1994 - Oct 10 1996

France

Post Doctoral

Université Versailles Saint-Quentin-en-Yvelines Sep 01 1993 - Aug 31 1994

France

ATER :: Chemistry

Education History

Université Pierre et Marie Curie Sep 01 1990 - Jan 31 1993

France

PHD

Université Pierre et Marie Curie Sep 15 1989 - Jul 01 1990

France

MSC

Publications

Amélie Laversin, Robin Dufossez, Raphaël Bolteau, Romain Duroux, Séverine Ravez, Sergio Hernandez-Tapia, Martin Fossart, Mathilde Coevoet, Maxime Liberelle, Saïd Yous, Nicolas Lebegue, Patricia Melnyk
Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists. Molecules (Basel, Switzerland) 29 (16) (2024)
Marie Tautou, Florian Descamps, Paul-Emmanuel Larchanché, Luc Buee, Jamal El Bakali, Patricia Melnyk, Nicolas Sergeant
A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APP Swe /PSEN1 ΔE9 Mice Model of Amyloid Pathology. International journal of molecular sciences 24 (6) (2023)
Marie Tautou, Florian Descamps, Paul-Emmanuel Larchanché, Luc Buee, Jamal El Bakali, Patricia Melnyk, Nicolas Sergeant
A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APP Swe /PSEN1 ΔE9 Mice Model of Amyloid Pathology. International journal of molecular sciences 24 (6) (2023)
Marie Tautou, Florian Descamps, Paul-Emmanuel Larchanché, Luc Buee, Jamal El Bakali, Patricia Melnyk, Nicolas Sergeant
A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APP Swe /PSEN1 ΔE9 Mice Model of Amyloid Pathology. International journal of molecular sciences 24 (6) (2023)
Benjamin Zagiel, Patricia Melnyk, Philippe Cotelle
Progress with YAP/TAZ-TEAD inhibitors: a patent review (2018-present). Expert opinion on therapeutic patents 32 (8) (2022)
Antoine Marchand, Alessia Sarchione, Panagiotis S Athanasopoulos, Hélène Bauderlique-Le Roy, Liesel Goveas, Romain Magnez, Matthieu Drouyer, Marco Emanuele, Franz Y Ho, Maxime Liberelle, Patricia Melnyk, Nicolas Lebegue, Xavier Thuru, R Jeremy Nichols, Elisa Greggio, Arjan Kortholt, Thierry Galli, Marie-Christine Chartier-Harlin, Jean-Marc Taymans
A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively. Cells 11 (6) (2022)
Christophe Mesangeau, Pascal Carato, Nicolas Renault, Mathilde Coevoet, Paul-Emmanuel Larchanché, Amélie Barczyk, Luc Buee, Nicolas Sergeant, Patricia Melnyk
Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles. International journal of molecular sciences 23 (21) (2022)
Bénédicte Oxombre, Fahima Madouri, Anne-Sophie Journé, Séverine Ravez, Eloise Woitrain, Pascal Odou, Nathalie Duhal, Sandro Ninni, David Montaigne, Nadira Delhem, Patrick Vermersch, Patricia Melnyk
Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis. International journal of molecular sciences 23 (19) (2022)
Pasquale Sileo, Clémence Simonin, Patricia Melnyk, Marie-Christine Chartier-Harlin, Philippe Cotelle
Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington's Disease and Other Neurodegenerative Disorders. Cells 11 (22) (2022)
Floriane Gibault, Manon Sturbaut, Mathilde Coevoet, Martine Pugnière, Ashley Burtscher, Frédéric Allemand, Patricia Melnyk, Wanjin Hong, Brian P Rubin, Ajaybabu V Pobbati, Jean-François Guichou, Philippe Cotelle, Fabrice Bailly
Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex. ChemMedChem 16 (18) (2021)
Floriane Gibault, Mathilde Coevoet, Manon Sturbaut, Amaury Farce, Nicolas Renault, Frédéric Allemand, Jean-François Guichou, Anne-Sophie Drucbert, Catherine Foulon, Romain Magnez, Xavier Thuru, Matthieu Corvaisier, Guillemette Huet, Philippe Chavatte, Patricia Melnyk, Fabrice Bailly, Philippe Cotelle
Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface. Cancers 10 (5) (2018)
Floriane Gibault, Fabrice Bailly, Matthieu Corvaisier, Mathilde Coevoet, Guillemette Huet, Patricia Melnyk, Philippe Cotelle
Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway. ChemMedChem 12 (12) (2017)

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Publication Activity (10 Years)

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Patricia Melnyk