Paul D Upton (Paul Upton)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 16

Top Venues

Cardiovascular research

Communications biology

Nature communications

Molecular genetics & genomic medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Bin Liu, Mujahid Azfar, Ekaterina Legchenko, James A West, Shaun Martin, Chris Van den Haute, Veerle Baekelandt, John Wharton, Luke Howard, Martin R Wilkins, Peter Vangheluwe, Nicholas W Morrell, Paul D Upton
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport. Cardiovascular research 120 (7) (2024)
Bin Liu, Mujahid Azfar, Ekaterina Legchenko, James A West, Shaun Martin, Chris Van den Haute, Veerle Baekelandt, John Wharton, Luke Howard, Martin R Wilkins, Peter Vangheluwe, Nicholas W Morrell, Paul D Upton
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport. Cardiovascular research (2024)
Bin Liu, Mujahid Azfar, Ekaterina Legchenko, James A West, Shaun Martin, Chris Van den Haute, Veerle Baekelandt, John Wharton, Luke Howard, Martin R Wilkins, Peter Vangheluwe, Nicholas W Morrell, Paul D Upton
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport. Cardiovascular research 120 (7) (2024)
Bin Liu, Mujahid Azfar, Ekaterina Legchenko, James A West, Shaun Martin, Chris Van den Haute, Veerle Baekelandt, John Wharton, Luke Howard, Martin R Wilkins, Peter Vangheluwe, Nicholas W Morrell, Paul D Upton
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport. Cardiovascular research 120 (7) (2024)
Tatyana Novoyatleva, Nabham Rai, Baktybek Kojonazarov, Swathi Veeroju, Isabel Ben-Batalla, Paola Caruso, Mazen Shihan, Nadine Presser, Elsa Götz, Carina Lepper, Sebastian Herpel, Grégoire Manaud, Frédéric Perros, Henning Gall, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, John Wharton, Martin R Wilkins, Paul D Upton, Sonja Loges, Nicholas W Morrell, Horst-Walter Birk, Ralph Theo Schermuly
Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. Communications biology 5 (1) (2022)
Benjamin J Dunmore, Rowena J Jones, Mark R Toshner, Paul D Upton, Nicholas W Morrell
Approaches to treat pulmonary arterial hypertension by targeting BMPR2: from cell membrane to nucleus. Cardiovascular research 117 (11) (2022)
Alexander J Ainscough, Timothy J Smith, Maike Haensel, Christopher J Rhodes, Adam Fellows, Harry J Whitwell, Eleni Vasilaki, Kelly Gray, Adrian Freeman, Luke S G Howard, John Wharton, Benjamin Dunmore, Paul D Upton, Martin R Wilkins, Joshua B Edel, Beata Wojciak-Stothard
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis. Communications biology 5 (1) (2022)
Paul D Upton, Susan Richards, Angela Bates, Karen Y Niederhoffer, Nicholas W Morrell, Susan Christian
A rare homozygous missense GDF2 (BMP9) mutation causing PAH in siblings: Does BMP10 status contribute? American journal of medical genetics. Part A (2022)
Paul D Upton, Benjamin J Dunmore, Wei Li, Nicholas W Morrell
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension. Developmental dynamics : an official publication of the American Association of Anatomists (2022)
Lidia Ruiz-Llorente, M Cristina Vega, Francisco J Fernández, Carmen Langa, Nicholas W Morrell, Paul D Upton, Carmelo Bernabéu
Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein. International journal of molecular sciences 22 (20) (2021)
Tatyana Novoyatleva, Nabham Rai, Baktybek Kojonazarov, Swathi Veeroju, Isabel Ben-Batalla, Paola Caruso, Mazen Shihan, Nadine Presser, Elsa Götz, Carina Lepper, Sebastian Herpel, Grégoire Manaud, Frédéric Perros, Henning Gall, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, John Wharton, Martin R Wilkins, Paul D Upton, Sonja Loges, Nicholas W Morrell, Horst-Walter Birk, Ralph Theo Schermuly
Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. Communications biology 4 (1) (2021)
Joshua Mark Hodgson, Lidia Ruiz-Llorente, Jamie McDonald, Oliver W J Quarrell, Kelechi Ugonna, James Bentham, Rebecca Mason, Jennifer M Martin, Alejandro Sifrim, Katie Bergstrom, Pinar Bayrak-Toydemir, Whitney L Wooderchak-Donahue, Nicholas W Morrell, Robin Condliffe, Carmelo Bernabéu, Paul D Upton
Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an "HHT-like" syndrome in children. Molecular genetics & genomic medicine (2021)
Paul D Upton, John E S Park, Patricia M De Souza, Rachel J Davies, Mark J D Griffiths, Stephen J Wort, Nicholas W Morrell
Endothelial protective factors BMP9 and BMP10 inhibit CCL2 release by human vascular endothelial cells. Journal of cell science 133 (14) (2020)
Ivana Nikolic, Lai-Ming Yung, Peiran Yang, Rajeev Malhotra, Samuel D Paskin-Flerlage, Teresa Dinter, Geoffrey A Bocobo, Kathleen E Tumelty, Anthony J Faugno, Luca Troncone, Megan E McNeil, Xiuli Huang, Kathryn R Coser, Carol S C Lai, Paul D Upton, Marie-José T H Goumans, Roham T Zamanian, C Gregory Elliott, Arthur Lee, Wei Zheng, Stephen P Berasi, Christine Huard, Nicholas W Morrell, Raymond T Chung, Richard W Channick, Kari E Roberts, Paul B Yu
Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension. American journal of respiratory and critical care medicine 199 (7) (2020)
Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M Salmon, Mark Southwood, Rajiv D Machado, Jennifer M Martin, Carmen M Treacy, Katherine Yates, Louise C Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala A Aldred, Harm J Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J Simon R Gibbs, Barbara Girerd, Arjan C Houweling, Luke Howard, Marc Humbert, David G Kiely, Gabor Kovacs, Robert V MacKenzie Ross, Shahin Moledina, I David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan Fredman Stein, Jay Suntharalingam, Emilia M Swietlik, Mark R Toshner, David A van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J Wort, Willem H Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D Upton, Martin R Wilkins, Richard C Trembath, Nicholas W Morrell
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nature communications 9 (1) (2018)
Liam A Hurst, Benjamin J Dunmore, Lu Long, Alexi Crosby, Rafia Al-Lamki, John Deighton, Mark Southwood, Xudong Yang, Marko Z Nikolic, Blanca Herrera, Gareth J Inman, John R Bradley, Amer A Rana, Paul D Upton, Nicholas W Morrell
TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nature communications 8 (2017)

Paul D Upton.css-eqlu8i{font-size:small;padding-left:4px;} (Paul Upton)

Publication Activity (10 Years)

Top Topics

Top Venues

Paul D Upton (Paul Upton)