Qun-Ying Lei (Qunying Lei)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Venues

Signal transduction and targeted therapy

Nature communications

Nature cell biology

Nature metabolism

Fudan University Shanghai Medical College

Fudan University Shanghai Medical College (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fudan University Shanghai Medical College Mar 12 2006

China

Prof.

Education History

Fudan University Shanghai Medical College Sep 01 1999 - Jul 01 2002

China

PHD :: Biochemistry and Molecular Biology

Publications

Miao Yin, Qun-Ying Lei
Targeting stromal metabolism in pancreatic ductal adenocarcinoma. Nature cell biology 26 (4) (2024)
Miao Yin, Qun-Ying Lei
Targeting stromal metabolism in pancreatic ductal adenocarcinoma. Nature cell biology (2024)
Ruiqian Zhao, Shijing Huang, Jingyu Li, Aihong Gu, Min-Jie Fu, Wei Hua, Ying Mao, Qun-Ying Lei, Boxun Lu, Wen-Yu Wen
Excessive STAU1 condensate drives mTOR translation and autophagy dysfunction in neurodegeneration. The Journal of cell biology 223 (8) (2024)
Miao Yin, Qun-Ying Lei
Targeting stromal metabolism in pancreatic ductal adenocarcinoma. Nature cell biology 26 (4) (2024)
Ruiqian Zhao, Shijing Huang, Jingyu Li, Aihong Gu, Min-Jie Fu, Wei Hua, Ying Mao, Qun-Ying Lei, Boxun Lu, Wen-Yu Wen
Excessive STAU1 condensate drives mTOR translation and autophagy dysfunction in neurodegeneration. The Journal of cell biology 223 (8) (2024)
Zhiyuan Xiang, Guixue Hou, Shanliang Zheng, Minqiao Lu, Tianyu Li, Qingyu Lin, Hao Liu, Xingwen Wang, Tianqi Guan, Yuhan Wei, Wenxin Zhang, Yi Zhang, Chaoran Liu, Li Li, Qun-Ying Lei, Ying Hu
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs. Proceedings of the National Academy of Sciences of the United States of America 121 (37) (2024)
Ruiqian Zhao, Shijing Huang, Jingyu Li, Aihong Gu, Min-Jie Fu, Wei Hua, Ying Mao, Qun-Ying Lei, Boxun Lu, Wen-Yu Wen
Excessive STAU1 condensate drives mTOR translation and autophagy dysfunction in neurodegeneration. The Journal of cell biology 223 (8) (2024)
Jingyu Li, Kang Zhu, Aihong Gu, Yiqing Zhang, Shijing Huang, Ronggui Hu, Weiguo Hu, Qun-Ying Lei, Wen-Yu Wen
Feedback regulation of ubiquitination and phase separation of HECT E3 ligases. Proceedings of the National Academy of Sciences of the United States of America 120 (33) (2023)
Lin Qian, Na Li, Xiao-Chen Lu, Mi-Die Xu, Ying Liu, Kaiyue Li, Yi Zhang, Kewen Hu, Yu-Ting Qi, Jun Yao, Ying-Li Wu, Wen-Yu Wen, Shengling Huang, Zheng-Jun Chen, Miao Yin, Qun-Ying Lei
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression. Nature metabolism (2023)
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yan-Ping Xu, Lei Lv
TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential. Cell discovery 9 (1) (2023)
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yan-Ping Xu, Lei Lv
Publisher Correction: TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential. Cell discovery 9 (1) (2023)
Miao-Lin Li, Si-Yi Cao, Jia Qu, Lei Zhang, Qiang Gao, Lei Wang, Miao Yin, Ying Liu, Ming-Zhu Lei, Qun-Ying Lei
S-adenosyl-L-methionine supplementation alleviates the destructed intestinal epithelium and inflammatory infiltration caused by Mat2a deficiency. Development (Cambridge, England) (2023)
Fan Zhang, Di Wang, Jintao Li, Ying Su, Suling Liu, Qun-Ying Lei, Miao Yin
Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism. Journal of molecular cell biology 14 (4) (2022)
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Correction To: Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal transduction and targeted therapy 7 (1) (2022)
Qi-Xiang Ma, Wen-Ying Zhu, Xiao-Chen Lu, Duo Jiang, Feng Xu, Jin-Tao Li, Lei Zhang, Ying-Li Wu, Zheng-Jun Chen, Miao Yin, Hai-Yan Huang, Qun-Ying Lei
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16. Nature metabolism 4 (1) (2022)
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Correction To: Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal transduction and targeted therapy 7 (1) (2022)
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Correction To: Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal transduction and targeted therapy 7 (1) (2022)
Xinchao Zhang, Shuyan Li, Jing He, Yunjie Jin, Ruonan Zhang, Wenjing Dong, Mingen Lin, Yajing Yang, Tongguan Tian, Yuefan Zhou, Yixin Xu, Qun-Ying Lei, Jing Zhang, Yang Zhang, Yanping Xu, Lei Lv
TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling. Cancer research 82 (11) (2022)
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal transduction and targeted therapy 7 (1) (2022)
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Correction To: Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal transduction and targeted therapy 7 (1) (2022)
Miao Yin, Qun-Ying Lei
BCAT2-BCKDH metabolon maintains BCAA homeostasis. Nature metabolism (2022)
Wei Huang, Na Li, Yi Zhang, Xu Wang, Miao Yin, Qun-Ying Lei
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner. Autophagy (2021)
Cuicui Liu, Jiankun Qiang, Qiaodan Deng, Jie Xia, Lu Deng, Lei Zhou, Dong Wang, Xueyan He, Ying Liu, Botao Zhao, Jinhui Lv, Zuoren Yu, Qun-Ying Lei, Zhi-Ming Shao, Xiao-Yong Zhang, Lixing Zhang, Suling Liu
ALDH1A1 Activity in Tumor-Initiating Cells Remodels Myeloid-Derived Suppressor Cells to Promote Breast Cancer Progression. Cancer research 81 (23) (2021)
Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui Zhang, Qun-Ying Lei, Zhi-Min Shao, Xiu-Wu Bian, Huiying Zhao, Lixing Zhang, Suling Liu
TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer. Nature communications 12 (1) (2021)
Jin-Tao Li, Kai-Yue Li, Ying Su, Yuan Shen, Ming-Zhu Lei, Fan Zhang, Miao Yin, Zheng-Jun Chen, Wen-Yu Wen, Wei-Guo Hu, Dan Su, Jia Qu, Qun-Ying Lei
Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization. National science review 9 (5) (2021)
Lin Qian, Fan Zhang, Miao Yin, Qun-Ying Lei
Cancer metabolism and dietary interventions. Cancer biology & medicine (2021)
Ming-Zhu Lei, Xu-Xu Li, Ye Zhang, Jin-Tao Li, Fan Zhang, Yi-Ping Wang, Miao Yin, Jia Qu, Qun-Ying Lei
Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth. Signal transduction and targeted therapy 5 (1) (2020)
Yi-Ping Wang, Jin-Tao Li, Jia Qu, Miao Yin, Qun-Ying Lei
Metabolite sensing and signaling in cancer. The Journal of biological chemistry 295 (33) (2020)
Jin-Tao Li, Miao Yin, Di Wang, Jian Wang, Ming-Zhu Lei, Ye Zhang, Ying Liu, Lei Zhang, Shao-Wu Zou, Li-Peng Hu, Zhi-Gang Zhang, Yi-Ping Wang, Wen-Yu Wen, Hao-Jie Lu, Zheng-Jun Chen, Dan Su, Qun-Ying Lei
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma. Nature cell biology 22 (2) (2020)
Ziheng Liu, Ying Yang, Aihong Gu, Jiawen Xu, Ying Mao, Haojie Lu, Weiguo Hu, Qun-Ying Lei, Zhouhua Li, Mingjie Zhang, Yu Cai, Wen-Yu Wen
Par complex cluster formation mediated by phase separation. Nature communications 11 (1) (2020)
Yifan Zhang, Qun-Ying Lei
Rewiring local immune milieu by boosting dendritic cell for pancreatic cancer treatment. Signal transduction and targeted therapy 5 (1) (2020)
Zhen Wang, Ziheng Liu, Xing Chen, Jingyu Li, Weiyi Yao, Shijing Huang, Aihong Gu, Qun-Ying Lei, Ying Mao, Wen-Yu Wen
A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases. Nature communications 10 (1) (2019)
Yuan Liu, Ji-Zheng Guo, Ying Liu, Kui Wang, Wencheng Ding, Hui Wang, Xiang Liu, Shengtao Zhou, Xiao-Chen Lu, Hong-Bin Yang, Chenyue Xu, Wei Gao, Li Zhou, Yi-Ping Wang, Weiguo Hu, Yuquan Wei, Canhua Huang, Qun-Ying Lei
Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth. Nature communications 9 (1) (2018)

Qun-Ying Lei.css-eqlu8i{font-size:small;padding-left:4px;} (Qunying Lei)

Publication Activity (10 Years)

Top Topics

Top Venues

Qun-Ying Lei (Qunying Lei)