Rachel E Simmonds

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 7

Top Venues

Wellcome open research

bioRxiv : the preprint server for biology

PLoS pathogens

Autophagy

University of Surrey

Imperial College (London) (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Surrey

United Kingdom

Senior Lecturer in Immunopathogenesis :: Dept of Microbial Sciences

Education History

Imperial College (London)

United Kingdom

PHD

Publications

Louise Tzung-Harn Hsieh, Belinda S Hall, Jane Newcombe, Tom A Mendum, Yagnesh Umrania, Michael J Deery, Wei Q Shi, Francisco J Salguero, Rachel E Simmonds
Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection. bioRxiv : the preprint server for biology (2023)
Louise Tzung-Harn Hsieh, Belinda S Hall, Jane Newcombe, Tom A Mendum, Yagnesh Umrania, Michael J Deery, Wei Q Shi, Francisco J Salguero, Rachel E Simmonds
Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection. bioRxiv : the preprint server for biology (2023)
Louise Tzung-Harn Hsieh, Scott J Dos Santos, Belinda S Hall, Joy Ogbechi, Aloysius D Loglo, Francisco Javier Salguero, Marie-Thérèse Ruf, Gerd Pluschke, Rachel E Simmonds
Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions. PLoS pathogens 18 (1) (2022)
Belinda S Hall, Scott J Dos Santos, Louise Tzung-Harn Hsieh, Maria Manifava, Marie-Thérèse Ruf, Gerd Pluschke, Nicholas T Ktistakis, Rachel E Simmonds
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity. Autophagy (2021)
Rachel E Simmonds
Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression. Wellcome open research 4 (2019)
Rachel E Simmonds
Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression. Wellcome open research (2019)
Joy Ogbechi, Belinda S Hall, Thomas Sbarrato, Jack Taunton, Anne E Willis, Ronald C Wek, Rachel E Simmonds
Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4. Cell death & disease 9 (3) (2018)

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Publication Activity (10 Years)

Top Topics

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Rachel E Simmonds