Shimin Le

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 11

Top Venues

Nature communications

APL bioengineering

The journal of physical chemistry letters

Proceedings of the National Academy of Sciences of the United States of America

National University of Singapore

National University of Singapore (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National University of Singapore Feb 01 2016

Singapore

Research Fellow :: Department of Physics

Education History

National University of Singapore Aug 01 2010 - Oct 31 2015

Singapore

PHD :: Mechanobiology Institute

Publications

Wen-Mao Huang, Jingzhun Liu, Shimin Le, Mingxi Yao, Yi Shi, Jie Yan
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein. APL bioengineering 8 (1) (2024)
Yuhang Zhang, Jingyi Du, Xian Liu, Fei Shang, Yunxin Deng, Jiaqing Ye, Yukai Wang, Jie Yan, Hu Chen, Miao Yu, Shimin Le
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification. Nature communications 15 (1) (2024)
Wen-Mao Huang, Jingzhun Liu, Shimin Le, Mingxi Yao, Yi Shi, Jie Yan
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein. APL bioengineering 8 (1) (2024)
Yuhang Zhang, Jingyi Du, Xian Liu, Fei Shang, Yunxin Deng, Jiaqing Ye, Yukai Wang, Jie Yan, Hu Chen, Miao Yu, Shimin Le
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification. Nature communications 15 (1) (2024)
Yuhang Zhang, Jingyi Du, Xian Liu, Fei Shang, Yunxin Deng, Jiaqing Ye, Yukai Wang, Jie Yan, Hu Chen, Miao Yu, Shimin Le
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification. Nature communications 15 (1) (2024)
Yuhang Zhang, Jingyi Du, Xian Liu, Fei Shang, Yunxin Deng, Jiaqing Ye, Yukai Wang, Jie Yan, Hu Chen, Miao Yu, Shimin Le
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification. Nature communications 15 (1) (2024)
Shimin Le, Miao Yu, Chaoyu Fu, Jonathon A Heier, Sterling Martin, Jeff Hardin, Jie Yan
Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America 121 (37) (2024)
Miao Yu, Jung-Hsuan Lu, Shimin Le, Jie Yan
Unexpected Low Mechanical Stability of Titin I27 Domain at Physiologically Relevant Temperature. The journal of physical chemistry letters 12 (33) (2021)
Yinan Wang, Mingxi Yao, Karen B Baker, Rosemarie E Gough, Shimin Le, Benjamin Thomas Goult, Jie Yan
Force-Dependent Interactions between Talin and Full-Length Vinculin. Journal of the American Chemical Society 143 (36) (2021)
Miao Yu, Zhihai Zhao, Zibo Chen, Shimin Le, Jie Yan
Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains. Nature communications 11 (1) (2020)
Shimin Le, Miao Yu, Jie Yan
Direct single-molecule quantification reveals unexpectedly high mechanical stability of vinculin-talin/α-catenin linkages. Science advances 5 (12) (2019)

Shimin Le.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Shimin Le