Show-Ling Shyng

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 16

Top Topics

Molecular Dynamics Simulations

Candida Albicans

Crystal Structure

Top Venues

Nature communications

bioRxiv : the preprint server for biology

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature communications 15 (1) (2024)
Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature communications 15 (1) (2024)
Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature communications 15 (1) (2024)
Assmaa ElSheikh, Camden M Driggers, Ha H Truong, Zhongying Yang, John Allen, Niel Henriksen, Katarzyna Walczewska-Szewc, Show-Ling Shyng
AI-Based Discovery and CryoEM Structural Elucidation of a K ATP Channel Pharmacochaperone. bioRxiv : the preprint server for biology (2024)
Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature communications 15 (1) (2024)
Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature communications 15 (1) (2024)
Camden M Driggers, Yi-Ying Kuo, Phillip Zhu, Assmaa ElSheikh, Show-Ling Shyng
Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. bioRxiv : the preprint server for biology (2023)
Camden M Driggers, Show-Ling Shyng
Mechanistic insights on KATP channel regulation from cryo-EM structures. The Journal of general physiology 155 (1) (2022)
Cécile Saint-Martin, Marine Cauchois-Le Mière, Emily Rex, Omar Soukarieh, Jean-Baptiste Arnoux, Julien Buratti, Delphine Bouvet, Thierry Frébourg, Pascaline Gaildrat, Show-Ling Shyng, Christine Bellanné-Chantelot, Alexandra Martins
Functional characterization of ABCC8 variants of unknown significance based on bioinformatics predictions, splicing assays, and protein analyses: Benefits for the accurate diagnosis of congenital hyperinsulinism. Human mutation 42 (4) (2021)
Min Woo Sung, Zhongying Yang, Camden M Driggers, Bruce L Patton, Barmak Mostofian, John D Russo, Daniel M Zuckerman, Show-Ling Shyng
Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proceedings of the National Academy of Sciences of the United States of America 118 (44) (2021)
Kandasamy Balamurugan, Babu Kavitha, Zhongying Yang, Viswanathan Mohan, Venkatesan Radha, Show-Ling Shyng
Functional characterization of activating mutations in the sulfonylurea receptor 1 (ABCC8) causing neonatal diabetes mellitus in Asian Indian children. Pediatric diabetes 20 (4) (2019)
Veronica Cochrane, Show-Ling Shyng
Leptin-induced Trafficking of KATP Channels: A Mechanism to Regulate Pancreatic β-cell Excitability and Insulin Secretion. International journal of molecular sciences 20 (11) (2019)
Gregory M Martin, Min Woo Sung, Zhongying Yang, Laura M Innes, Balamurugan Kandasamy, Larry L David, Craig Yoshioka, Show-Ling Shyng
Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM. eLife 8 (2019)
Yi Wu, Dale A Fortin, Veronica A Cochrane, Pei-Chun Chen, Show-Ling Shyng
NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells. The Journal of biological chemistry 292 (37) (2017)
Gregory M Martin, Craig Yoshioka, Emily A Rex, Jonathan F Fay, Qing Xie, Matthew R Whorton, James Z Chen, Show-Ling Shyng
Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. eLife 6 (2017)
Gregory M Martin, Balamurugan Kandasamy, Frank Dimaio, Craig Yoshioka, Show-Ling Shyng
Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM. eLife 6 (2017)