Simon J Cook

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Venues

The Biochemical journal

Nature communications

The FEBS journal

NAR cancer

Babraham Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Babraham Institute

United Kingdom

Senior Group Leader :: Signalling Laboratory

Onyx Pharmaceuticals

United States

Assoc Staff Scientist, Staff Scientist & Project Manager :: RAS Group and Inflammation Project

Onyx Pharmaceuticals

United States

Post-Doctoral Fellow :: RAS Group

Publications

Laura Weatherdon, Kate Stuart, Megan Cassidy, Alberto Moreno de la Gándara, Hanneke Okkenhaug, Markus Muellener, Grahame Mckenzie, Simon J Cook, Rebecca Gilley
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway. The Biochemical journal 481 (6) (2024)
Laura Weatherdon, Kate Stuart, Megan Cassidy, Alberto Moreno de la Gándara, Hanneke Okkenhaug, Markus Muellener, Grahame Mckenzie, Simon J Cook, Rebecca Gilley
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway. The Biochemical journal 481 (6) (2024)
Laura Weatherdon, Kate Stuart, Megan Cassidy, Alberto Moreno de la Gándara, Hanneke Okkenhaug, Markus Muellener, Grahame Mckenzie, Simon J Cook, Rebecca Gilley
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway. The Biochemical journal 481 (6) (2024)
Prasanna Channathodiyil, Kieron May, Anne Segonds-Pichon, Paul D Smith, Simon J Cook, Jonathan Houseley
Escape from G1 arrest during acute MEK inhibition drives the acquisition of drug resistance. NAR cancer 4 (4) (2022)
Jack A Prescott, Kathryn Balmanno, Jennifer P Mitchell, Hanneke Okkenhaug, Simon J Cook
IKKα plays a major role in canonical NF-κB signalling in colorectal cells. The Biochemical journal 479 (3) (2022)
Jack A Prescott, Jennifer P Mitchell, Simon J Cook
Inhibitory feedback control of NF-κB signalling in health and disease. The Biochemical journal 478 (13) (2021)
Pamela A Lochhead, Julie A Tucker, Natalie J Tatum, Jinhua Wang, David Oxley, Andrew M Kidger, Victoria P Johnson, Megan A Cassidy, Nathanael S Gray, Martin E M Noble, Simon J Cook
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors. Nature communications 11 (1) (2020)
Matthew J Sale, Emma Minihane, Noel R Monks, Rebecca Gilley, Frances M Richards, Kevin P Schifferli, Courtney L Andersen, Emma J Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan Ian Jodrell, Paul D Smith, Simon J Cook
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors. Nature communications 10 (1) (2019)
Andrew M Kidger, Simon J Cook
De-RSKing ERK - regulation of ERK1/2-RSK dissociation by phosphorylation within a disordered motif. The FEBS journal 285 (1) (2019)
Andrew M Kidger, Joanne M Munck, Harpreet K Saini, Kathryn Balmanno, Emma Minihane, Aurelie Courtin, Brent Graham, Marc O'Reilly, Richard Odle, Simon J Cook
Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2. Molecular cancer therapeutics 19 (2) (2019)
Simon J Cook, Kate Stuart, Rebecca Gilley, Matthew J Sale
Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling. The FEBS journal 284 (24) (2017)
Nicola J Darling, Kathryn Balmanno, Simon J Cook
ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death. PloS one 12 (9) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Simon J Cook