Stephen Cusack

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Topics

Crystal Structure

Structural Basis

Top Venues

Nature communications

Nucleic acids research

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Benoit Arragain, Tim Krischuns, Martin Pelosse, Petra Drncova, Martin Blackledge, Nadia Naffakh, Stephen Cusack
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nature communications 15 (1) (2024)
Maud Dupont, Tim Krischuns, Quentin Giai Gianetto, Sylvain Paisant, Stefano Bonazza, Jean-Baptiste Brault, Thibaut Douché, Benoît Arragain, Alberto Florez-Prada, Joel I Perez-Perri, Matthias W Hentze, Stephen Cusack, Mariette Matondo, Catherine Isel, David Gary Courtney, Nadia Naffakh
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic acids research 52 (12) (2024)
Tim Krischuns, Benoit Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nature communications 15 (1) (2024)
Maud Dupont, Tim Krischuns, Quentin Giai Gianetto, Sylvain Paisant, Stefano Bonazza, Jean-Baptiste Brault, Thibaut Douché, Benoît Arragain, Alberto Florez-Prada, Joel I Perez-Perri, Matthias W Hentze, Stephen Cusack, Mariette Matondo, Catherine Isel, David Gary Courtney, Nadia Naffakh
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic acids research 52 (12) (2024)
Benoit Arragain, Tim Krischuns, Martin Pelosse, Petra Drncova, Martin Blackledge, Nadia Naffakh, Stephen Cusack
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nature communications 15 (1) (2024)
Benoit Arragain, Tim Krischuns, Martin Pelosse, Petra Drncova, Martin Blackledge, Nadia Naffakh, Stephen Cusack
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nature communications 15 (1) (2024)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Carola Busch, Morlin Milewski, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural snapshots of phenuivirus cap-snatching and transcription. Nucleic acids research 52 (10) (2024)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Carola Busch, Morlin Milewski, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural snapshots of phenuivirus cap-snatching and transcription. Nucleic acids research 52 (10) (2024)
Maud Dupont, Tim Krischuns, Quentin Giai Gianetto, Sylvain Paisant, Stefano Bonazza, Jean-Baptiste Brault, Thibaut Douché, Benoît Arragain, Alberto Florez-Prada, Joel I Perez-Perri, Matthias W Hentze, Stephen Cusack, Mariette Matondo, Catherine Isel, David Gary Courtney, Nadia Naffakh
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic acids research 52 (12) (2024)
Maud Dupont, Tim Krischuns, Quentin Giai Gianetto, Sylvain Paisant, Stefano Bonazza, Jean-Baptiste Brault, Thibaut Douché, Benoît Arragain, Alberto Florez-Prada, Joel I Perez-Perri, Matthias W Hentze, Stephen Cusack, Mariette Matondo, Catherine Isel, David Gary Courtney, Nadia Naffakh
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic acids research 52 (12) (2024)
Tim Krischuns, Benoit Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nature communications 15 (1) (2024)
Maud Dupont, Tim Krischuns, Quentin Giai Gianetto, Sylvain Paisant, Stefano Bonazza, Jean-Baptiste Brault, Thibaut Douché, Benoît Arragain, Alberto Florez-Prada, Joel I Perez-Perri, Matthias W Hentze, Stephen Cusack, Mariette Matondo, Catherine Isel, David Gary Courtney, Nadia Naffakh
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic acids research (2024)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Carola Busch, Morlin Milewski, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural snapshots of phenuivirus cap-snatching and transcription. Nucleic acids research (2024)
Tim Krischuns, Benoit Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nature communications 15 (1) (2024)
Tim Krischuns, Benoit Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nature communications 15 (1) (2024)
Benoit Arragain, Martin Pelosse, Albert Thompson, Stephen Cusack
Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nature communications 14 (1) (2023)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic acids research (2023)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic acids research 51 (3) (2023)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic acids research (2023)
Mathilde Lethier, Karine Huard, Michael Hons, Adrien Favier, Bernhard Brutscher, Elisabetta Boeri Erba, Derek W Abbott, Stephen Cusack, Erika Pellegrini
Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface. Life science alliance 6 (11) (2023)
Harry M Williams, Sigurdur R Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald, Emmanuelle R J Quemin, Maria Rosenthal
Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic acids research 51 (3) (2023)
Benoit Arragain, Quentin Durieux Trouilleton, Florence Baudin, Jan Provaznik, Nayara Azevedo, Stephen Cusack, Guy Schoehn, Hélène Malet
Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nature communications 13 (1) (2022)
Tim Krischuns, Catherine Isel, Petra Drncova, Maria Lukarska, Alexander Pflug, Sylvain Paisant, Vincent Navratil, Stephen Cusack, Nadia Naffakh
Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. PLoS pathogens 18 (5) (2022)
Anne-Emmanuelle Foucher, Leila Touat-Todeschini, Ariadna B Juarez-Martinez, Auriane Rakitch, Hamida Laroussi, Claire Karczewski, Samira Acajjaoui, Montserrat Soler-López, Stephen Cusack, Cameron David Mackereth, André Verdel, Jan Kadlec
Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex. Nature communications 13 (1) (2022)
Tomas Kouba, Dominik Vogel, Sigurdur R Thorkelsson, Emmanuelle R J Quemin, Harry M Williams, Morlin Milewski, Carola Busch, Stephan Gunther, Kay Grünewald, Maria Rosenthal, Stephen Cusack
Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nature communications 12 (1) (2021)
Stephen Cusack, Maria Rosenthal
Errors in the deposited SFTSV L protein structure. Nature microbiology 6 (5) (2021)
Aldo R Camacho-Zarco, Sissy Kalayil, Damien Maurin, Nicola Salvi, Elise Delaforge, Sigrid Milles, Malene Ringkjøbing Jensen, Darren J Hart, Stephen Cusack, Martin Blackledge
Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A. Nature communications 11 (1) (2020)
Benoit Arragain, Grégory Effantin, Piotr Gerlach, Juan Reguera, Guy Schoehn, Stephen Cusack, Hélène Malet
Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nature communications 11 (1) (2020)
Tomas Kouba, Petra Drncová, Stephen Cusack
Structural snapshots of actively transcribing influenza polymerase. Nature structural & molecular biology 26 (6) (2019)
Shinya Omoto, Valentina Speranzini, Takashi Hashimoto, Takeshi Noshi, Hiroto Yamaguchi, Makoto Kawai, Keiko Kawaguchi, Takeki Uehara, Takao Shishido, Akira Naito, Stephen Cusack
Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Scientific reports 8 (1) (2018)
Marios G Koliopoulos, Mathilde Lethier, Annemarthe G van der Veen, Kevin Haubrich, Janosch Hennig, Eva Kowalinski, Rebecca V Stevens, Stephen R Martin, Caetano Reis E Sousa, Stephen Cusack, Katrin Rittinger
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition. Nature communications 9 (1) (2018)
Erika Pellegrini, Ambroise Desfosses, Arndt Wallmann, Wiebke Manuela Schulze, Kristina Rehbein, Philippe Mas, Luca Signor, Stephanie Gaudon, Grasilda Zenkeviciute, Michael Hons, Helene Malet, Irina Gutsche, Carsten Sachse, Guy Schoehn, Hartmut Oschkinat, Stephen Cusack
RIP2 filament formation is required for NOD2 dependent NF-κB signalling. Nature communications 9 (1) (2018)
Wiebke Manuela Schulze, Frank Stein, Mandy Rettel, Max Nanao, Stephen Cusack
Author Correction: Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting. Nature communications 9 (1) (2018)
Wiebke Manuela Schulze, Frank Stein, Mandy Rettel, Max Nanao, Stephen Cusack
Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting. Nature communications 9 (1) (2018)
Erika Pellegrini, Luca Signor, Saurabh Singh, Elisabetta Boeri Erba, Stephen Cusack
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PloS one 12 (5) (2017)
Maria Rosenthal, Nadja Gogrefe, Dominik Vogel, Juan Reguera, Bianka Rauschenberger, Stephen Cusack, Stephan Günther, Sophia Reindl
Structural insights into reptarenavirus cap-snatching machinery. PLoS pathogens 13 (5) (2017)
Wiebke Manuela Schulze, Stephen Cusack
Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nature communications 8 (1) (2017)