Stephen L Bearne

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 15

Top Venues

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Biochemistry

ChemMedChem

Chemistry (Weinheim an der Bergstrasse, Germany)

Dalhousie University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dalhousie University Jul 1o 1996

Canada

Professor :: Biochemistry & Molecular Biology; Chemistry

Publications

Nigel G J Richards, Stephen L Bearne, Yuki Goto, Emily J Parker
Reactivity and mechanism in chemical and synthetic biology. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Oliver P Kuehm, Joshua A Hayden, Stephen L Bearne
A Phenylboronic Acid-Based Transition State Analogue Yields Nanomolar Inhibition of Mandelate Racemase. Biochemistry (2023)
Stephen L Bearne
Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Nigel G J Richards, Stephen L Bearne, Yuki Goto, Emily J Parker
Reactivity and mechanism in chemical and synthetic biology. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Stephen L Bearne
Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Nigel G J Richards, Stephen L Bearne, Yuki Goto, Emily J Parker
Reactivity and mechanism in chemical and synthetic biology. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Stephen L Bearne
Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Nigel G J Richards, Stephen L Bearne, Yuki Goto, Emily J Parker
Reactivity and mechanism in chemical and synthetic biology. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Stephen L Bearne
Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Stephen L Bearne, Chen-Jun Guo, Ji-Long Liu
GTP-Dependent Regulation of CTP Synthase: Evolving Insights into Allosteric Activation and NH 3 Translocation. Biomolecules 12 (5) (2022)
Thomas D Gillis, Stephen L Bearne
Effects of the 5'-Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase Catalysis and Filament Formation: Implications for Repurposing Antiviral Agents against SARS-CoV-2. ChemMedChem (2022)
Colin D Douglas, Lia Grandinetti, Nicole M Easton, Oliver P Kuehm, Joshua A Hayden, Meghan C Hamilton, Martin St Maurice, Stephen L Bearne
Slow-Onset, Potent Inhibition of Mandelate Racemase by 2-Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery. Biochemistry (2021)
Amar Nath Sharma, Lia Grandinetti, Erin R Johnson, Martin St Maurice, Stephen L Bearne
Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center. Biochemistry 59 (33) (2020)
Stephen L Bearne
Through the Looking Glass: Chiral Recognition of Substrates and Products at the Active Sites of Racemases and Epimerases. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (46) (2020)
Stephen L Bearne
The role of Brønsted base basicity in estimating carbon acidity at enzyme active sites: a caveat. Organic & biomolecular chemistry 17 (30) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Stephen L Bearne