Swee Lay Lay Thein (Swee Lay Thein, Swee Lay Thein)

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 26

Top Venues

Blood

Blood advances

Proceedings of the National Academy of Sciences of the United States of America

Nature genetics

NIH / NHLBI

University of Malaya (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

NIH / NHLBI Mar 23 2015

United States

Senior Investigator/ Branch Chief :: Sickle Cell Branch

Education History

University of Malaya

Malaysia

BSC :: Faculty of Medicine

Publications

Kang Le, Xunde Wang, Jonathan Chu, Maureen Lundt, Yuan Yee Lee, Anna Conrey, Ingrid C Frey, Silvia Giannini, Penelope A Kosinski, John M Hausman, Philip S Low, Neal Jeffries, Sanjay Arvind Desai, Swee Lay Lay Thein
Activating pyruvate kinase improves red blood cell integrity by reducing band 3 tyrosine phosphorylation. Blood advances (2024)
Alexis Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances (2024)
Alexis K Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew M Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances 8 (7) (2024)
Alexis K Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew M Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances 8 (7) (2024)
Dina S Parekh, William A Eaton, Swee Lay Lay Thein
Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease. Blood 143 (10) (2024)
Alexis Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances (2024)
Alexis K Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew M Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances 8 (7) (2024)
Dina S Parekh, William A Eaton, Swee Lay Lay Thein
Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease. Blood 143 (10) (2024)
Dina S Parekh, William A Eaton, Swee Lay Lay Thein
Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease. Blood 143 (10) (2024)
Alexis K Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Selami Demirci, Khaled Essawi, Bjorg Gudmundsdottir, Malikiya Hinds, Julia DiNicola, Quan Li, William A Eaton, Troy Cellmer, Xunde Wang, Swee Lay Lay Thein, Elizabeth R Macari, Sara VanNest, Matthew M Hsieh, Melissa Bonner, Francis J Pierciey, John F Tisdale
In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation. Blood advances 8 (7) (2024)
Dina S Parekh, William A Eaton, Swee Lay Lay Thein
Recent developments on using pyruvate kinase activators as a new approach for treating sickle cell disease. Blood (2023)
Xunde Wang, Kate Gardner, Mickias B Tegegn, Clifton L Dalgard, Camille Alba, Stephan Menzel, Hamel Patel, Mehdi Pirooznia, Yi-Ping Fu, Fayaz T Seifuddin, Swee Lay Lay Thein
Genetic variants of PKLR are associated with acute pain in sickle cell disease. Blood advances 6 (11) (2022)
Julia Zhe Xu, Anna Conrey, Ingrid Frey, Eveline Gwaabe, Laurel A Menapace, Laxminath Tumburu, Maureen Lundt, Timothy Lequang, Quan Li, Kristen Glass, Emily B Dunkelberger, Varsha Iyer, Heidi Mangus, Charles Kung, Lenny Dang, Penelope A Kosinski, Peter Hawkins, Neal Jeffries, William A Eaton, Swee Lay Lay Thein
A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease. Blood 140 (19) (2022)
Swee Lay Lay Thein, Vandana Sachdev
Diffuse myocardial fibrosis as an SCD biomarker. Blood 140 (11) (2022)
Julia Zhe Xu, Swee Lay Lay Thein
Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches. Blood 139 (20) (2022)
Belhu Metaferia, Troy Cellmer, Emily B Dunkelberger, Quan Li, Eric R Henry, James Hofrichter, Dwayne Staton, Matthew M Hsieh, Anna K Conrey, John F Tisdale, Arnab K Chatterjee, Swee Lay Lay Thein, William A Eaton
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America 119 (40) (2022)
Eric R Henry, Belhu Metaferia, Quan Li, Julia Harper, Robert B Best, Kristen E Glass, Troy Cellmer, Emily B Dunkelberger, Anna Conrey, Swee Lay Lay Thein, H Franklin Bunn, William A Eaton
Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin. Blood 138 (13) (2021)
Vandana Sachdev, Xin Tian, Yuan Gu, James Nichols, Stanislav Sidenko, Wen Li, Andrea Beri, W Austin Layne, Darlene Allen, Colin O Wu, Swee Lay Lay Thein
A phenotypic risk score for predicting mortality in sickle cell disease. British journal of haematology 192 (5) (2021)
Laxminath Tumburu, Shohini Ghosh-Choudhary, Fayaz T Seifuddin, Emilia A Barbu, Simon Yang, Maliha M Ahmad, Lauren H W Wilkins, Ilker Tunc, Ishwarya Sivakumar, James S Nichols, Pradeep K Dagur, Shutong Yang, Luis E F Almeida, Zenaide M N Quezado, Christian A Combs, Eric Lindberg, Christopher K E Bleck, Jun Zhu, Arun S Shet, Jay H Chung, Mehdi Pirooznia, Swee Lay Lay Thein
Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease. Blood 137 (22) (2021)
Laxminath Tumburu, Swee Lay Lay Thein
Targeting ZNF410 as a potential β-hemoglobinopathy therapy. Nature genetics 53 (5) (2021)
Eric R Henry, Troy Cellmer, Emily B Dunkelberger, Belhu Metaferia, James Hofrichter, Quan Li, David Ostrowski, Rodolfo Ghirlando, John M Louis, Stéphane Moutereau, Frédéric Galactéros, Swee Lay Lay Thein, Pablo Bartolucci, William A Eaton
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America 117 (26) (2020)
Xunde Wang, Julia Z Xu, Anna Conrey, Laurel Mendelsohn, Daniel Shriner, Mehdi Pirooznia, Swee Lay Lay Thein
Whole genome sequence-based haplotypes reveal a single origin of the 1393 bp HBB deletion. Journal of medical genetics 57 (8) (2020)
Sebastian Vogel, Taruna Arora, Xunde Wang, Laurel Mendelsohn, James Nichols, Darlene Allen, Arun S Shet, Christian A Combs, Zenaide M N Quezado, Swee Lay Lay Thein
The platelet NLRP3 inflammasome is upregulated in sickle cell disease via HMGB1/TLR4 and Bruton tyrosine kinase. Blood advances 2 (20) (2019)
Stephan Menzel, Swee Lay Lay Thein
Genetic Modifiers of Fetal Haemoglobin in Sickle Cell Disease. Molecular diagnosis & therapy 23 (2) (2019)
Emilia Alina Barbu, Venina M Dominical, Laurel Mendelsohn, Swee Lay Lay Thein
Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease. PloS one 14 (12) (2019)
Swee Lay Lay Thein, Jo Howard
How I treat the older adult with sickle cell disease. Blood 132 (17) (2018)
Claire C Sharpe, Swee Lay Lay Thein
How I treat renal complications in sickle cell disease. Blood 123 (24) (2014)

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Publication Activity (10 Years)

Top Topics

Top Venues

Swee Lay Lay Thein (Swee Lay Thein, Swee Lay Thein)