Titia de Lange

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 41

Top Venues

Nature

Science (New York, N.Y.)

Nucleic acids research

bioRxiv : the preprint server for biology

University of Amsterdam (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Amsterdam

Netherlands

PHD

Publications

Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger
DNA-PK controls Apollo's access to leading-end telomeres. Nucleic acids research 52 (8) (2024)
Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger
DNA-PK controls Apollo's access to leading-end telomeres. Nucleic acids research 52 (8) (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger
DNA-PK controls Apollo's access to leading-end telomeres. Nucleic acids research (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger
DNA-PK controls Apollo's access to leading-end telomeres. Nucleic acids research 52 (8) (2024)
Alexander Stuart, Titia de Lange
Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia. bioRxiv : the preprint server for biology (2024)
Alexander Stuart, Titia de Lange
Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia. bioRxiv : the preprint server for biology (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Charles G Kinzig, George Zakusilo, Kaori K Takai, Logan R Myler, Titia de Lange
ATR blocks telomerase from converting DNA breaks into telomeres. Science (New York, N.Y.) 383 (6684) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature (2024)
Hiroyuki Takai, Valentina Aria, Pâmela C Carvalho Borges, Joseph T P Yeeles, Titia de Lange
CST-polymerase α-primase solves a second telomere end-replication problem. Nature 627 (8004) (2024)
Ceylan Sonmez, Beatrice Toia, Patrik Eickhoff, Andreea Medeea Matei, Michael El Beyrouthy, Björn Wallner, Max E Douglas, Titia de Lange, Francisca Lottersberger
DNA-PK controls Apollo's access to leading-end telomeres. Nucleic acids research 52 (8) (2024)
Logan R Myler, Beatrice Toia, Cara K Vaughan, Kaori Takai, Andreea M Matei, Peng V Wu, Tanya T Paull, Titia de Lange, Francisca Lottersberger
DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature structural & molecular biology (2023)
Hiroyuki Takai, Valentina Aria, Pamela Borges, Joseph T P Yeeles, Titia de Lange
CST-Polymeraseα-primase solves a second telomere end-replication problem. bioRxiv : the preprint server for biology (2023)
Sarah W Cai, Titia de Lange
CST-Polα/Primase: the second telomere maintenance machine. Genes & development (2023)
Zi-Ning Choo, Julie M Behr, Aditya Deshpande, Kevin Hadi, Xiaotong Yao, Huasong Tian, Kaori Takai, George Zakusilo, Joel Rosiene, Arnaud Da Cruz Paula, Jorge S Reis-Filho, Jeremy Setton, Nadeem Riaz, Simon N Powell, Klaus J Busam, Alexander N Shoushtari, Charlotte Ariyan, Jorge Sergio Reis-Filho, Titia de Lange, Marcin Imielinski
Most large structural variants in cancer genomes can be detected without long reads. Nature genetics (2023)
Sarah W Cai, Hiroyuki Takai, Thomas Walz, Titia de Lange
Structural basis of CST-Polα/Primase recruitment and regulation by POT1 at telomeres. bioRxiv : the preprint server for biology (2023)
Zachary Mirman, Sarah Cai, Titia de Lange
CST/Polα/primase-mediated fill-in synthesis at DSBs. Cell cycle (Georgetown, Tex.) (2022)
Zhe Yang, Keshav Sharma, Titia de Lange
TRF1 uses a noncanonical function of TFIIH to promote telomere replication. Genes & development 36 (17-18) (2022)
Sarah W Cai, John C Zinder, Vladimir Svetlov, Martin W Bush, Evgeny Nudler, Thomas Walz, Titia de Lange
Cryo-EM structure of the human CST-Polα/primase complex in a recruitment state. Nature structural & molecular biology 29 (8) (2022)
Zachary Mirman, Nanda Kumar Sasi, Ashleigh King, J Ross Chapman, Titia de Lange
53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis. Nature cell biology 24 (1) (2022)
Sally M Dewhurst, Xiaotong Yao, Joel Rosiene, Huasong Tian, Julie Behr, Nazario Bosco, Kaori K Takai, Titia de Lange, Marcin Imielinski
Structural variant evolution after telomere crisis. Nature communications 12 (1) (2021)
Logan R Myler, Charles G Kinzig, Nanda K Sasi, George Zakusilo, Sarah W Cai, Titia de Lange
The evolution of metazoan shelterin. Genes & development 35 (23-24) (2021)
Isabelle Schmutz, Arjen R Mensenkamp, Kaori K Takai, Maaike Haadsma, Liesbeth Spruijt, Richarda M de Voer, Seunga Sara Choo, Franziska K Lorbeer, Emma J van Grinsven, Dirk Hockemeyer, Marjolijn Cj Jongmans, Titia de Lange
TINF2 is a haploinsufficient tumor suppressor that limits telomere length. eLife 9 (2020)
Courtney A Lovejoy, Kaori Takai, Michael S Huh, David J Picketts, Titia de Lange
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity. PLoS biology 18 (1) (2020)
John Maciejowski, Aikaterini Chatzipli, Alexandra Dananberg, Kevan Chu, Eleonore Toufektchan, Leszek J Klimczak, Dmitry A Gordenin, Peter J Campbell, Titia de Lange
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis. Nature genetics 52 (9) (2020)
Titia de Lange
What I got wrong about shelterin. The Journal of biological chemistry 293 (27) (2018)
Katja Kratz, Titia de Lange
Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b. The Journal of biological chemistry 293 (37) (2018)
Isabelle Schmutz, Leonid Timashev, Wei Xie, Dinshaw J Patel, Titia de Lange
TRF2 binds branched DNA to safeguard telomere integrity. Nature structural & molecular biology 24 (9) (2017)

Titia de Lange.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Titia de Lange