Xosé R Bustelo (X R Bustelo, Xose R Bustelo)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 42

Top Topics

Breast Cancer Cells

Gene Expression

Top Venues

Nature communications

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Javier Conde, Isabel Fernández-Pisonero, L Francisco Lorenzo-Martín, Rocío García-Gómez, Berta Casar, Piero Crespo, Xosé R Bustelo
The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis. Molecular oncology (2024)
Ana Martín-Vega, Laura Ruiz-Peinado, Rocío García-Gómez, Ana Herrero, Dalia de la Fuente-Vivas, Swetha Parvathaneni, Rubén Caloto, Marta Morante, Alexander von Kriegsheim, Xosé R Bustelo, David B Sacks, Berta Casar, Piero Crespo
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species. Science advances 9 (7) (2023)
Alejandro Hortal, Marta Lacuna, Claudia Cifuentes, Miguel Alcoceba, Xosé R Bustelo, Marcos González, Balbino Alarcón
An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3' Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients. Cancers 15 (3) (2023)
Ana Martín-Vega, Laura Ruiz-Peinado, Rocío García-Gómez, Ana Herrero, Dalia de la Fuente-Vivas, Swetha Parvathaneni, Rubén Caloto, Marta Morante, Alexander von Kriegsheim, Xosé R Bustelo, David B Sacks, Berta Casar, Piero Crespo
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species. Science advances 9 (7) (2023)
Alejandro M Hortal, Ana Villanueva, Irene Arellano, Cristina Prieto, Pilar Mendoza, Xosé R Bustelo, Balbino Alarcón
Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies. Cancers 15 (24) (2023)
Alejandro M Hortal, Ana Villanueva, Irene Arellano, Cristina Prieto, Pilar Mendoza, Xosé R Bustelo, Balbino Alarcón
Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies. Cancers 15 (24) (2023)
Ana Martín-Vega, Laura Ruiz-Peinado, Rocío García-Gómez, Ana Herrero, Dalia de la Fuente-Vivas, Swetha Parvathaneni, Rubén Caloto, Marta Morante, Alexander von Kriegsheim, Xosé R Bustelo, David B Sacks, Berta Casar, Piero Crespo
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species. Science advances 9 (7) (2023)
Ana Martín-Vega, Laura Ruiz-Peinado, Rocío García-Gómez, Ana Herrero, Dalia de la Fuente-Vivas, Swetha Parvathaneni, Rubén Caloto, Marta Morante, Alexander von Kriegsheim, Xosé R Bustelo, David B Sacks, Berta Casar, Piero Crespo
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species. Science advances 9 (7) (2023)
Alejandro Hortal, Marta Lacuna, Claudia Cifuentes, Miguel Alcoceba, Xosé R Bustelo, Marcos González, Balbino Alarcón
An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3' Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients. Cancers 15 (3) (2023)
Alejandro M Hortal, Ana Villanueva, Irene Arellano, Cristina Prieto, Pilar Mendoza, Xosé R Bustelo, Balbino Alarcón
Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies. Cancers 15 (24) (2023)
Marta Lacuna, Alejandro M Hortal, Claudia Cifuentes, Tania Gonzalo, Miguel Alcoceba, Miguel Bastos, Xosé R Bustelo, Marcos González, Balbino Alarcón
Characterization of Three Somatic Mutations in the 3'UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia. Cells 12 (23) (2023)
Rubén Caloto, Luis Francisco Lorenzo-Martín, Víctor Quesada, Arkaitz Carracedo, Xosé R Bustelo
CiberAMP: An R Package to Identify Differential mRNA Expression Linked to Somatic Copy Number Variations in Cancer Datasets. Biology 11 (10) (2022)
Javier Robles-Valero, Lucía Fernández-Nevado, Myriam Cuadrado, Luis Francisco Lorenzo-Martín, Isabel Fernández-Pisonero, Antonio Abad, Esther Redín, Luis Montuenga, Dionisio Martín-Zanca, Anna Bigas, Moisés Mallo, Mercedes Dosil, Xosé R Bustelo
Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model. Molecular oncology 16 (19) (2022)
Laura Clavaín, Isabel Fernández-Pisonero, Nieves Movilla, Luis Francisco Lorenzo-Martín, Blanca Nieto, Antonio Abad, Rósula García-Navas, Clara Llorente-González, Manuel A Sanchez-Martin, Miguel Vicente-Manzanares, Eugenio Santos, Balbino Alarcón, José Manuel García Aznar, Mercedes Dosil, Xosé R Bustelo
Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors. Oncogene (2022)
Bright Asare-Bediako, Yvonne Adu-Agyeiwaah, Antonio Abad, Sergio Li Calzi, Jason Levi Floyd, Ram Prasad, Mariana D Dupont, Richmond Asare-Bediako, Xosé R Bustelo, Maria B Grant
Hematopoietic Cells Influence Vascular Development in the Retina. Cells 11 (20) (2022)
R C Nayak, K H Chang, A K Singh, Michael Kotliar, M Desai, A M Wellendorf, M Wunderlich, J Bartram, Benjamin E Mizukawa, Myriam Cuadrado, Phillip J Dexheimer, Artem Barski, Xosé R Bustelo, Nicolas N Nassar, Jose A Cancelas
Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nature communications 13 (1) (2022)
Luis Francisco Lorenzo-Martín, Mauricio Menacho-Márquez, Natalia Fernández-Parejo, Sonia Rodríguez-Fdez, Gloria Pascual, Antonio Abad, Piero Crespo, Mercedes Dosil, Salvador Aznar Benitah, Xosé R Bustelo
The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function. Oncogene 41 (24) (2022)
Blanca Nieto, Sonia G Gaspar, Russell T Sapio, Laura Clavaín, Xosé R Bustelo, Dimitri G Pestov, Mercedes Dosil
Efficient fractionation and analysis of ribosome assembly intermediates in human cells. RNA biology (2021)
Ana Nacarino-Palma, Claudia M Rejano-Gordillo, Francisco J González-Rico, Ana Ordiales-Talavero, Ángel C Román, Myriam Cuadrado, Xosé R Bustelo, Jaime M Merino, Pedro María Fernández-Salguero
Loss of Aryl Hydrocarbon Receptor Favors K-RasG12D-Driven Non-Small Cell Lung Cancer. Cancers 13 (16) (2021)
Sonia Rodríguez-Fdez, Xosé R Bustelo
Rho GTPases in Skeletal Muscle Development and Homeostasis. Cells 10 (11) (2021)
Sonia Rodríguez-Fdez, Luis Francisco Lorenzo-Martín, Salvatore Fabbiano, Mauricio Menacho Márquez, Vincent Sauzeau, Mercedes Dosil, Xosé R Bustelo
New Functions of Vav Family Proteins in Cardiovascular Biology, Skeletal Muscle, and the Nervous System. Biology 10 (9) (2021)
Javier Conde Aranda, Isabel Fernández-Pisonero, Myriam Cuadrado, Antonio Abad, Javier Robles-Valero, Xosé R Bustelo
Distinct Roles of Vav Family Members in Adaptive and Innate Immune Models of Arthritis. Biomedicines 9 (6) (2021)
Javier Robles-Valero, Lucía Fernández-Nevado, Luis Francisco Lorenzo-Martín, Myriam Cuadrado, Isabel Fernández-Pisonero, Sonia Rodríguez-Fdez, Elsa N Astorga-Simón, Antonio Abad, Ruben Caloto, Xosé R Bustelo
Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. The EMBO journal 40 (22) (2021)
Fernando C Baltanás, Cynthia Mucientes-Valdivieso, Luis Francisco Lorenzo-Martín, Natalia Fernández-Parejo, Rósula García-Navas, Carmen Segrelles, Nuria Calzada, Rocío Fuentes-Mateos, Jesus M Paramio, Xosé R Bustelo, Eugenio Santos
Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis. Cancers 13 (9) (2021)
Joan Sala-Gaston, Arturo Martinez-Martinez, Leonardo Pedrazza, Luis Francisco Lorenzo-Martín, Rubén Caloto, Xosé R Bustelo, Francesc Ventura Pujol, Jose Luis Rosa
HERC Ubiquitin Ligases in Cancer. Cancers 12 (6) (2020)
Sonia Rodríguez-Fdez, Luis Francisco Lorenzo-Martín, Isabel Fernández-Pisonero, Begoña Porteiro, Christelle Veyrat-Durebex, Daniel Beiroa, Omar Al-Massadi, Antonio Abad, Carlos Diéguez, Roberto Coppari, Ruben Nogueiras, Xosé R Bustelo
Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis. Nature communications 11 (1) (2020)
Parastoo Shahrouzi, Ianire Astobiza, Ana R Cortazar, Verónica Torrano, Alice Macchia, Juana M Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L Martinez-Chantar, Xosé R Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona, Arkaitz Carracedo
Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis. Cancers 12 (9) (2020)
Blanca Nieto, Sonia G Gaspar, Giulia Moriggi, Dimitri G Pestov, Xosé R Bustelo, Mercedes Dosil
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis. Nature communications 11 (1) (2020)
Luis Francisco Lorenzo-Martín, Mauricio Menacho Márquez, Xosé R Bustelo
Drug Vulnerabilities and Disease Prognosis Linked to the Stem Cell-Like Gene Expression Program Triggered by the RHO GTPase Activator VAV2 in Hyperplastic Keratinocytes and Head and Neck Cancer. Cancers 12 (9) (2020)
Luis Francisco Lorenzo-Martín, Sonia Rodríguez-Fdez, Salvatore Fabbiano, Antonio Abad, María C García-Macías, Mercedes Dosil, Myriam Cuadrado, Javier Robles-Valero, Xosé R Bustelo
Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor. Oncogene 39 (28) (2020)
Luis Francisco Lorenzo-Martín, Natalia Fernández-Parejo, Mauricio Menacho-Márquez, Sonia Rodríguez-Fdez, Javier Robles-Valero, Sonia Zumalave, Salvatore Fabbiano, Gloria Pascual, Juana M García-Pedrero, Antonio Abad, María Carmen García-Macías, Nazareno González, Pablo Lorenzano-Menna, Miguel A Pavón, Rogelio González-Sarmiento, Carmen Segrelles, Jesus M Paramio, José M C Tubío, Juan Pablo Rodrigo, Salvador Aznar Benitah, Myriam Cuadrado, Xosé R Bustelo
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma. Nature communications 11 (1) (2020)
Sonia Rodríguez-Fdez, Carmen Citterio, Luis Francisco Lorenzo-Martín, Jesús Baltanás-Copado, Clara Llorente-González, Senena Corbalan-García, Miguel Vicente-Manzanares, Xosé R Bustelo
Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output. Cells 8 (12) (2019)
Sonia Rodríguez-Fdez, Xosé R Bustelo
The Vav GEF Family: An Evolutionary and Functional Perspective. Cells 8 (5) (2019)
Ana R Cortazar, Veronica Torrano, Natalia Martín-Martín, Alfredo Caro-Maldonado, Laura Camacho, Ivana Hermanova, Elizabeth Guruceaga, Luis Francisco Lorenzo-Martín, Ruben Caloto, Roger R Gomis, Iñigo Apaolaza, Victor Quesada, Jan Trka, Antonio Gomez-Muñoz, Silvestre Vincent, Xosé R Bustelo, Francisco J Planes, Ana María Aransay, Arkaitz Carracedo
CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets. Cancer research 78 (21) (2018)
Pilar Mendoza, Nuria Martínez-Martín, Elena R Bovolenta, Diana Reyes-Garau, Pablo Hernansanz-Agustín, Pilar Delgado, Manuel D Diaz-Muñoz, Clara L Oeste, Isabel Fernández-Pisonero, Ester Castellano, Antonio Martínez-Ruiz, Diego Alonso López, Eugenio Santos, Xosé R Bustelo, Tomohiro Kurosaki, Balbino Alarcón
R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes. Science signaling 11 (532) (2018)
Pilar Liceras-Boillos, David Jimeno, Rósula García-Navas, L Francisco Lorenzo-Martín, Mauricio Menacho-Marquez, Carmen Segrelles, Carmela Gómez, Nuria Calzada, Rocío Fuentes-Mateos, Jesús M Paramio, Xosé R Bustelo, Fernando C Baltanás, Eugenio Santos
Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis. Molecular and cellular biology 38 (16) (2018)
L Francisco Lorenzo-Martín, Carmen Citterio, Mauricio Menacho-Márquez, Javier Conde, Romain M Larive, Sonia Rodríguez-Fdez, Ramon Garcia-Escudero, Javier Robles-Valero, Myriam Cuadrado, Isabel Fernández-Pisonero, Mercedes Dosil, María A Sevilla, María J Montero, Pedro M Fernández-Salguero, Jesus M Paramio, Xosé R Bustelo
Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms. Oncogene 38 (2) (2018)
Javier Robles-Valero, L Francisco Lorenzo-Martín, Isabel Fernández-Pisonero, Xosé R Bustelo
Rho guanosine nucleotide exchange factors are not such bad guys after all in cancera. Small GTPases 11 (4) (2018)
Berta Casar, Andrew P Badrock, Iñaki Jiménez, Imanol Arozarena, Paula Colón-Bolea, L Francisco Lorenzo-Martín, Irene Barinaga-Rementería, Jorge Barriuso, Vincenzo Cappitelli, Daniel J Donoghue, Xosé R Bustelo, Adam F L Hurlstone, Piero Crespo
RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation. Nature communications 9 (1) (2018)
Georg Hilfenhaus, Dai Phuong Nguyen, Jonathan Freshman, Divya Prajapati, Feiyang Ma, Dana Song, Safiyyah Ziyad, Myriam Cuadrado, Matteo Pellegrini, Xosé R Bustelo, M Luisa Iruela-Arispe
Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers. The Journal of cell biology 217 (8) (2018)
Guillermo de Cárcer, Paulina Wachowicz, Sara Martínez-Martínez, Jorge Oller, Nerea Méndez-Barbero, Beatriz Escobar, Alejandra González-Loyola, Tohru Takaki, Aicha El Bakkali, Juan A Cámara, Luis Jesús Jiménez-Borreguero, Xosé R Bustelo, Marta Cañamero, Francisca Mulero, María de Los Ángeles Sevilla, María Jose Montero, Juan Miguel Redondo, Marcos Malumbres
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis. Nature medicine 23 (8) (2017)
Antonio Castro-Castro, Olivia Muriel, Miguel A Del Pozo, Xosé R Bustelo
Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation. PloS one 11 (11) (2016)
Shuyong Zhu, Chengjiang Zhao, Yingying Wu, Qiaoqiao Yang, Aiyun Shao, Tiepeng Wang, Jianfu Wu, Yanqing Yin, Yandong Li, Jincan Hou, Xinhua Zhang, Guomin Zhou, Xiaosong Gu, Xiaomin Wang, Xosé R Bustelo, Jiawei Zhou
Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking. Nature neuroscience 18 (8) (2015)
Salvatore Fabbiano, Mauricio Menacho-Márquez, Javier Robles-Valero, Miguel Pericacho, Adela Matesanz-Marín, Carmen García-Macías, María A Sevilla, M J Montero, Balbino Alarcón, José M López-Novoa, Pilar Martín, Xosé R Bustelo
Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions. Molecular and cellular biology 35 (20) (2015)
Virginia Ojeda, Antonio Castro-Castro, Xosé R Bustelo
Coronin1 proteins dictate rac1 intracellular dynamics and cytoskeletal output. Molecular and cellular biology 34 (18) (2014)
Salvatore Fabbiano, Mauricio Menacho-Márquez, María A Sevilla, Julián Albarrán-Juárez, Yi Zheng, Stefan Offermanns, María J Montero, Xosé R Bustelo
Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells. Molecular and cellular biology 34 (24) (2014)