A dark side to NS1 antibodies?

Published in: The Journal of experimental medicine (2021)

The NS1 protein of flaviviruses is taking center stage. Recent work has made it an attractive target for development of vaccines and immunotherapeutics. Cavazzoni and colleagues (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210580) now reveal a dark side to NS1, linking it to the development of self-reactive antibodies.

Keyphrases

dengue virus
zika virus
genome wide
protein protein
dna methylation
small molecule
aedes aegypti