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Clinical value of cell-based assays in the characterisation of seronegative myasthenia gravis.

Valentina DamatoGregorio SpagniGabriele MonteMark WoodhallLeslie JacobsonSilvia FalsoThomas SmithRaffaele IorioPatrick J WatersSarosh R IraniAngela VincentAmelia Evoli
Published in: Journal of neurology, neurosurgery, and psychiatry (2022)
Around one-third of patients with SNMG had AChR or MuSK antibodies by l-CBAs, which were efficiently detected with a combined l-CBA. The results in this large and unselected cohort of patients with MG demonstrate the diagnostic usefulness of performing CBAs and the importance of making these tests more widely available.
Keyphrases
  • myasthenia gravis
  • single cell
  • cell therapy
  • high throughput
  • stem cells
  • mesenchymal stem cells
  • bone marrow