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IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.

Ling GongGang LiuHonglan ZhuCaihong LiPengmei LiChanglu LiuHongbo TangKaifeng WuJie WuDaishun LiuXiaoping Tang
Published in: BMC pulmonary medicine (2020)
These results suggest that IL-32 induces EMT in A549 cells by triggering ER stress, and IL-32 may be a novel marker for IPF.
Keyphrases
  • induced apoptosis
  • endoplasmic reticulum stress
  • epithelial mesenchymal transition
  • signaling pathway
  • cell cycle arrest
  • oxidative stress
  • transforming growth factor
  • idiopathic pulmonary fibrosis
  • cell death