2-Day versus C-reactive protein guided antibiotherapy with levofloxacin in acute COPD exacerbation: A randomized controlled trial.
Msolli Mohamed AmineMessous SelmaSekma AdelBel Haj Ali KhaoulaKhalil Mohamed HasseneTrabelsi ImenAbdelghani AhmedBen Brahim NadiaBen Dhaya YosraRazgallah RabieGrissa Mohamed HabibBeltaief KaoutharMethamem MehdiBelguith AsmaBouida WahidBoukef RiadhBoubaker HamdiNouira Semirnull nullPublished in: PloS one (2021)
Levofloxacin once daily for 2 days had similar efficacy compared to CRP-guided in AECOPD. This short course treatment decreased antibiotic consumption which would improve patient compliance and reduce adverse effects.