Oxytocin reduces the functional connectivity between brain regions involved in eating behavior in men with overweight and obesity.

Liya KeremNouchine HadjikhaniLaura HolsenElizabeth A LawsonFranziska Plessow

Published in: International journal of obesity (2005) (2019)

In men with overweight and obesity, OXT attenuates the functional connectivity between the VTA and food motivation brain regions in response to high-calorie visual food images. These findings could partially explain the observed anorexigenic effect of OXT, providing insight into the mechanism through which OXT ameliorates food cue-induced reward anticipation in patients with obesity. Additional studies are ongoing to further delineate the anorexigenic effect of OXT in obesity.

Keyphrases

resting state
functional connectivity
weight loss
insulin resistance
metabolic syndrome
type diabetes
human health
weight gain
high fat diet induced
middle aged
deep learning
convolutional neural network
mouse model
machine learning
optical coherence tomography