Biochanin A attenuates zymosan-induced arthritis in mice similarly to 17-β estradiol: an alternative to hormone replacement therapy?

Franciel Batista FelixJessica Maria Dantas AraújoElindayane Vieira de SouzaVanessa PinhoEnilton Aparecido CamargoCristiane Bani CorrêaRenata Grespan

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)

BCA has a notable anti-inflammatory effect, similar to 17-β estradiol, and is especially effective for treatment of ZIA. These results suggest that BCA may be promising for the treatment of postmenopausal arthritis.

Keyphrases

replacement therapy
rheumatoid arthritis
smoking cessation
adipose tissue
metabolic syndrome
oxidative stress
bone mineral density
skeletal muscle
estrogen receptor
insulin resistance
body composition
drug induced