Replication stress-induced Exo1 phosphorylation is mediated by Rad53/Pph3 and Exo1 nuclear localization is controlled by 14-3-3 proteins.

Nagaraja ChappidiGiuseppe De GregorioStefano Ferrari

Published in: Cell division (2019)

By shedding light on the mechanism of Exo1 control, these data underscore the importance of post-translational modifications and protein interactions in the regulation of DNA end resection.

Keyphrases

stress induced
dna damage
circulating tumor
electronic health record
dna repair
single molecule
big data
protein protein
protein kinase
binding protein
data analysis
artificial intelligence