Readily Accessible and Predictable Naphthalene-Based Two-Photon Fluorophore with Full Visible-Color Coverage.

Ja Young KooCheol Ho HeoYoung-Hee ShinDahahm KimChang Su LimBong Rae ChoHwan Myung KimJong Beom Park

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2016)

Herein we report 22 acedan-derived, two-photon fluorophores with synthetic feasibility and full coverage of visible wavelength emission. The emission wavelengths were predicted by computational analysis, which enabled us to visualize multicolor images by two-photon excitation with single wavelength, and to design a turn-on, two-photon fluorescence sensor for endogenous H2 O2 in Raw 264.7 macrophage and rat brain hippocampus ex vivo.

Keyphrases

living cells
fluorescent probe
single molecule
monte carlo
adipose tissue
affordable care act
deep learning
energy transfer
convolutional neural network
machine learning
optical coherence tomography
sensitive detection
solid state