Association of complement C3 with incident type 2 diabetes and the mediating role of BMI: A 10-year follow-up study.

Jing JiangHao WangKang LiuShiqi HeZhaoyang LiYu YuanKuai YuPinpin LongJing WangTingyue DiaoXiaomin ZhangMeian HeHuan GuoTangchun Wu

Published in: The Journal of clinical endocrinology and metabolism (2022)

The present prospective study revealed that C3 could be an early biomarker for incident T2DM, and that BMI might play a potential mediating role in the C3-T2DM associations, which provided clues for the pathogenesis of diabetes.

Keyphrases

glycemic control
type diabetes
cardiovascular disease
body mass index
weight gain
insulin resistance
weight loss
single cell
risk assessment
skeletal muscle
human health