Sanziguben polysaccharides inhibit diabetic nephropathy through NF-κB-mediated anti-inflammation.

Kang ZhouJianing ZhangChang LiuLijuan OuFan WangYang YuYumei WangShasha Bai

Published in: Nutrition & metabolism (2021)

NF-κB plays a critical role in the development of DN induced by STZ and HG. Furthermore, SZP can attenuate the NF-κB-mediated progression of diabetic nephropathy, improve DN through anti-inflammation.

Keyphrases

diabetic nephropathy
oxidative stress
signaling pathway
lps induced
pi k akt
nuclear factor
diabetic rats
inflammatory response
toll like receptor
immune response