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Transcriptomic underpinnings of high and low mirror aggression zebrafish behaviours.

Florian ReichmannJohannes PilicSlave TrajanoskiWilliam H J Norton
Published in: BMC biology (2022)
The current study shows that selective breeding based of the mirror aggression phenotype induces strong, heritable changes in behaviour and gene expression within the brain of zebrafish suggesting a strong genetic basis for this behaviour. Our transcriptomic analysis of fish selectively bred for high and low levels of mirror aggression revealed specific transcriptomic signatures induced by selective breeding and mirror aggression and thus provides a large and novel resource of candidate genes for future study.
Keyphrases
  • gene expression
  • single cell
  • rna seq
  • genome wide
  • multiple sclerosis
  • blood brain barrier