Sustained low-efficiency dialysis for metformin-associated lactic acidosis in patients with acute kidney injury.

Paolo GrecoGiuseppe RegolistiUmberto MaggioreElena FerioliFilippo FaniCarlo LocatelliElisabetta ParentiCaterina MaccariIlaria GandolfiniEnrico Fiaccadori

Published in: Journal of nephrology (2018)

A 16-h SLED session, performed with either conventional dialysis machines or CRRT machines, allows effective metformin removal in patients with MALA and AKI. However, due to possible post-SLED rebound in serum metformin levels, one additional dialysis treatment is required the following day in the majority of patients.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
acute kidney injury
cardiac surgery
ejection fraction
newly diagnosed
combination therapy