A circular RNA produced by LRBA promotes cirrhotic mouse liver regeneration through facilitating the ubiquitination degradation of p27.

Liangliang XuJinfu ZhangLi LiPeng WangXiaobo ZhengJianchen LuoShuqi ZhangLian LiPengsheng YiYanfang ZhangTao YanLiang XieLei FengMing ZhangMingQing Xu

Published in: Liver international : official journal of the International Association for the Study of the Liver (2023)

We conclude that circLRBA is a novel growth promoter in liver regeneration and a potential therapeutic target related to deficiency of cirrhotic liver regeneration.

Keyphrases

stem cells
dna methylation
gene expression
transcription factor
climate change
human health
smoking cessation