Individual risk calculator to predict lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study.
Annieke W GotinkSteffi Elisabeth Maria van de VenFiebo J C Ten KateDaan NieboerLucia SuzukiBas L A M WeustenLodewijk A A BrosensRichard van HillegersbergLorenza Alvarez HerreroCees A SeldenrijkAlaa AlkhalafFreek C P MollErik J SchoonIneke van LijnschotenThjon J TangHans van der ValkWouter B NagengastGursah Kats-UgurluJohn T M PlukkerMartin H M G HoubenJaap S van der LaanRoos E PouwJacques J G H M BergmanSybren L MeijerMark I van Berge HenegouwenBas P L WijnhovenPieter Jan F de JongeMichael DoukasMarco J BrunoKatharina BiermannArjun D KochPublished in: Endoscopy (2021)
A third of patients with pT1b EAC experienced metastases within 5 years. The probability of developing post-resection metastases was estimated with a personalized predicted risk score incorporating tumor invasion depth, tumor size, and lymphovascular invasion. This model requires external validation before implementation into clinical practice.