Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome-Wide Association and Mendelian Randomization Study.
Kosuke InoueTatsuhiko NaitoRyosuke FujiKyuto SoneharaKenichi YamamotoRyuta BabaTakaya KodamaYu OtagakiAkira OkadaKiyotaka ItchoKazuhiro KobukeHaruya Ohnonull nullTakayuki MorisakiNoboru HattoriAtsushi GotoTetsuo NishikawaKenji OkiYukinori OkadaPublished in: Journal of the American Heart Association (2024)
Our 2-sample Mendelian randomization study revealed that PA had increased risks of CAD, CHF, and stroke. These findings highlight that early and active screening of PA is critical to prevent future cardiovascular events.