18F-PSMA-1007 PET/CT at 60 and 120 minutes in patients with prostate cancer: biodistribution, tumour detection and activity kinetics.
Kambiz RahbarAli Afshar-OromiehMartin BögemannStefan WagnerMichael SchäfersLars SteggerMatthias WeckesserPublished in: European journal of nuclear medicine and molecular imaging (2018)
PCa lesions show a significant increase in 18F-PSMA-1007 uptake at 120 min compared with 60 min after injection. In addition, accumulation of the tracer in the urinary bladder was very low leading to improved contrast of adjacent PCa lesions. Increasing accumulation in the liver may limit the sensitivity of the tracer in detecting liver metastases.